2023
Comparison of the prognostic value between quantification and visual estimation of coronary calcification from attenuation CT in patients undergoing SPECT myocardial perfusion imaging
Feher A, Pieszko K, Shanbhag A, Lemley M, Miller R, Huang C, Miras L, Liu Y, Gerber J, Sinusas A, Miller E, Slomka P. Comparison of the prognostic value between quantification and visual estimation of coronary calcification from attenuation CT in patients undergoing SPECT myocardial perfusion imaging. The International Journal Of Cardiovascular Imaging 2023, 40: 185-193. PMID: 37845406, PMCID: PMC466934, DOI: 10.1007/s10554-023-02980-1.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsCoronary artery calcificationMyocardial perfusion imagingCT myocardial perfusion imagingSPECT/CT myocardial perfusion imagingArtery calcificationPrognostic valuePrior coronary stentingAdverse cardiovascular eventsSimilar prognostic valueSPECT myocardial perfusionREFINE SPECT registrySPECT/CTCardiovascular eventsCAC scoringCalcium scoreCoronary calcificationCoronary stentingPrognostic utilitySingle centerCoronary arteryLow doseMyocardial perfusionPerfusion imagingSurvival analysisTime and event-specific deep learning for personalized risk assessment after cardiac perfusion imaging
Pieszko K, Shanbhag A, Singh A, Hauser M, Miller R, Liang J, Motwani M, Kwieciński J, Sharir T, Einstein A, Fish M, Ruddy T, Kaufmann P, Sinusas A, Miller E, Bateman T, Dorbala S, Di Carli M, Berman D, Dey D, Slomka P. Time and event-specific deep learning for personalized risk assessment after cardiac perfusion imaging. Npj Digital Medicine 2023, 6: 78. PMID: 37127660, PMCID: PMC10151323, DOI: 10.1038/s41746-023-00806-x.Peer-Reviewed Original ResearchAcute coronary syndromeMajor adverse cardiovascular eventsMyocardial perfusion imagingCause deathAdverse cardiovascular eventsModifiable risk factorsPrediction of deathPersonalized risk assessmentCardiovascular eventsCoronary syndromeClinical featuresPrognostic valueRisk factorsExternal cohortStandard clinical interpretationPerfusion imagingAbnormality measuresCardiac perfusionTime pointsPatients' explanationsClinical interpretationExternal validationDeathPatientsRisk assessment
2020
Coronary Computed Tomography Angiography Compared With Single Photon Emission Computed Tomography Myocardial Perfusion Imaging as a Guide to Optimal Medical Therapy in Patients Presenting With Stable Angina: The RESCUE Trial
Stillman A, Gatsonis C, Lima J, Liu T, Snyder B, Cormack J, Malholtra V, Schnall M, Udelson J, Hoffmann U, Woodard P, Kim M, Hegde V, Kenny, Afaq M, Clouse M, Malhotra V, Cole, Al‐Khori F, Scherer M, Rothenberg F, Kirsch J, Shah A, Quyyumi A, Engberding N, Becker C, Li D, Pantelic M, Duerinckx A, Martin, Schrank J, Zachariah, Jacob R, Borges A, Roberge E, Truong Q, Edelman R, Akers S, Marsh K, Kemp, Reingold J, Chilakapati V, Osborne J, Lui K, Gomes A, Bajpai A, del Rio J, Singh, Thompson B, Rivard A, Jha S, Mavromatis K, Woodard P, Sinusas A. Coronary Computed Tomography Angiography Compared With Single Photon Emission Computed Tomography Myocardial Perfusion Imaging as a Guide to Optimal Medical Therapy in Patients Presenting With Stable Angina: The RESCUE Trial. Journal Of The American Heart Association 2020, 9: e017993. PMID: 33283579, PMCID: PMC7955393, DOI: 10.1161/jaha.120.017993.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsOptimal medical therapyAcute myocardial infarctionMedical therapyStable anginaMyocardial perfusion imagingMyocardial infarctionSingle photon emissionNegative CCTAHazard ratioRescue trialPerfusion imagingFirst major adverse cardiovascular eventTomography myocardial perfusion imagingSPECT myocardial perfusion imagingAdverse cardiovascular eventsOutcomes of patientsTomography myocardial perfusionFirst imaging testPhoton emissionCCTA armPositive CCTACardiovascular eventsSegment involvementOutcome trials