2023
Predictors of Neurodevelopment in Microcephaly Associated with Congenital Zika Syndrome: A Prospective Study
Mattos A, Rastely-Junior V, Pires M, Aguilar J, Lessa M, Regis C, Wanderley M, Leony J, Bouzon J, Ballalai V, Vieira C, Carvalho G, Almeida J, Nery N, Leal R, Costa F, Ko A, Reis M, Oliveira-Filho J. Predictors of Neurodevelopment in Microcephaly Associated with Congenital Zika Syndrome: A Prospective Study. Children 2023, 10: 1831. PMID: 38136033, PMCID: PMC10741834, DOI: 10.3390/children10121831.Peer-Reviewed Original ResearchCongenital Zika syndromeEvans indexZika syndromeHead circumferenceNeurodevelopmental delayMedian head circumferenceBayley-III scoresCT scan analysisMicrocephaly AssociatedNeurodevelopmental examinationProspective studyVentricle enlargementBrain abnormalitiesCongenital manifestationsMultiprofessional teamGross motorNeonate periodDevelopmental anomaliesDevelopmental delaySyndromeMicrocephalyBlinded expertsMonthsChildrenCircumference
2022
Unequal burden of Zika-associated microcephaly among populations with public and private healthcare in Salvador, Brazil
Aromolaran A, Araujo K, Ladines-Lim JB, Nery N, do Rosário MS, Rastely VN, Archanjo G, Daltro D, da Silveira Carvalho G, Pimentel K, de Almeida JRM, de Siqueira IC, Ribeiro HC, Oliveira-Filho J, de Oliveira D, Henriques DF, Rodrigues SG, da Costa Vasconcelos P, de Almeida ARP, Sacramento GA, Cruz JS, Sarno M, de Paula Freitas B, Mattos A, Khouri R, Reis MG, Ko AI, Costa F. Unequal burden of Zika-associated microcephaly among populations with public and private healthcare in Salvador, Brazil. International Journal Of Infectious Diseases 2022, 120: 201-204. PMID: 35470025, PMCID: PMC9119857, DOI: 10.1016/j.ijid.2022.04.030.Peer-Reviewed Original ResearchConceptsZIKV exposurePregnant womenSocioeconomic statusRelative disease burdenCongenital Zika syndromeZika virus epidemicLow socioeconomic statusZika syndromeClinical presentationDisease burdenSimilar prevalenceSerologic dataDifferent socioeconomic statusS HospitalHospitalLarge hospitalsMicrocephalyStudy centersVirus epidemicWomenPositive associationInfantsUnequal burdenHigh rateExposure rate
2019
Zika Virus Infection — After the Pandemic
Musso D, Ko AI, Baud D. Zika Virus Infection — After the Pandemic. New England Journal Of Medicine 2019, 381: 1444-1457. PMID: 31597021, DOI: 10.1056/nejmra1808246.Peer-Reviewed Original ResearchRisk of Zika microcephaly correlates with features of maternal antibodies
Robbiani DF, Olsen PC, Costa F, Wang Q, Oliveira TY, Nery N, Aromolaran A, do Rosário MS, Sacramento GA, Cruz JS, Khouri R, Wunder EA, Mattos A, de Paula Freitas B, Sarno M, Archanjo G, Daltro D, Carvalho GBS, Pimentel K, de Siqueira IC, de Almeida JRM, Henriques DF, Lima JA, Vasconcelos PFC, Schaefer-Babajew D, Azzopardi SA, Bozzacco L, Gazumyan A, Belfort R, Alcântara AP, Carvalho G, Moreira L, Araujo K, Reis MG, Keesler RI, Coffey LL, Tisoncik-Go J, Gale M, Rajagopal L, Waldorf K, Dudley DM, Simmons HA, Mejia A, O’Connor D, Steinbach RJ, Haese N, Smith J, Lewis A, Colgin L, Roberts V, Frias A, Kelleher M, Hirsch A, Streblow DN, Rice CM, MacDonald MR, de Almeida ARP, Van Rompay KKA, Ko AI, Nussenzweig MC. Risk of Zika microcephaly correlates with features of maternal antibodies. Journal Of Experimental Medicine 2019, 216: 2302-2315. PMID: 31413072, PMCID: PMC6781003, DOI: 10.1084/jem.20191061.Peer-Reviewed Original ResearchConceptsMaternal antibodiesFetal brain damageSerum antibody responseZika virus infectionInfected pregnanciesMicrocephalic infantsAntibody responsePregnant macaquesRisk factorsBrain damageVirus infectionCongenital abnormalitiesLow titersBrazilian womenMicrocephalyTitersPregnancyZIKVAntibodiesBirthRiskInfantsInfectionAbnormalitiesFlaviviruses