2024
Letter to the Editor Regarding “Utility of Magnetic Resonance Imaging for Ligamentous Injury in Cervical Spine Trauma: A 2-Year Consecutive Case Cohort”
Malhotra A, Wu X, Khunte M. Letter to the Editor Regarding “Utility of Magnetic Resonance Imaging for Ligamentous Injury in Cervical Spine Trauma: A 2-Year Consecutive Case Cohort”. World Neurosurgery 2024, 187: 277. PMID: 38970196, DOI: 10.1016/j.wneu.2024.01.137.Peer-Reviewed Original ResearchAutomated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion
Mak A, Matouk C, Avery E, Behland J, Haider S, Frey D, Madai V, Vajkoczy P, Griessenauer C, Zand R, Hendrix P, Abedi V, Sanelli P, Falcone G, Petersen N, Sansing L, Sheth K, Payabvash S, Malhotra A. Automated detection of early signs of irreversible ischemic change on CTA source images in patients with large vessel occlusion. PLOS ONE 2024, 19: e0304962. PMID: 38870240, PMCID: PMC11175522, DOI: 10.1371/journal.pone.0304962.Peer-Reviewed Original ResearchConceptsDiffusion-weighted imagingLarge vessel occlusionIrreversible ischemic changesPoor functional outcomeFunctional outcomesIschemic changesInfarct volumeAlberta Stroke Program Early CT ScorePredicting poor functional outcomeVessel occlusionFollow-up diffusion-weighted imagingAnterior circulation LVO strokeCTA source imagesReceiver operating characteristic curveExpert human readersPredicting final infarctionASPECTS regionsAdmission CTANon-inferior performanceBaseline CTACT scoreFinal infarctEndovascular therapyHU attenuationValidation cohortSalary Equity in Academic Radiology Relative to Other Clinical Specialties
Malhotra A, Futela D, Khunte M, Ebrahimian S, Lee C, Wu X, Payabvash S, Gandhi D. Salary Equity in Academic Radiology Relative to Other Clinical Specialties. Academic Radiology 2024 PMID: 38782618, DOI: 10.1016/j.acra.2024.05.012.Peer-Reviewed Original ResearchAmerican Association of Medical CollegesClinical specialtiesU.S. medical schoolsSalary equitySalary survey dataFaculty membersSalary inequitiesRadiology facultyMedical specialtiesMedical schoolsFull-time facultyRadiology physiciansSpecialtyMedical CollegeAmerican AssociationRadiology departmentCompensation dataProfessor rankWomenSurvey dataWomen faculty membersFacultyRadiologyRadiological relationsAssistanceSalary equity in academic medicine physicians
Malhotra A, Futela D, Khunte M, Moily N, Wu X, Payabvash S, Gandhi D. Salary equity in academic medicine physicians. The American Journal Of The Medical Sciences 2024 PMID: 38772441, DOI: 10.1016/j.amjms.2024.05.009.Peer-Reviewed Original ResearchAdvances in chronic subdural hematoma and membrane imaging
Chen H, Colasurdo M, Malhotra A, Gandhi D, Bodanapally U. Advances in chronic subdural hematoma and membrane imaging. Frontiers In Neurology 2024, 15: 1366238. PMID: 38725642, PMCID: PMC11079242, DOI: 10.3389/fneur.2024.1366238.Peer-Reviewed Original ResearchChronic subdural hematomaMiddle meningeal artery embolizationSubdural hematomaDeterminants of disease recurrenceChronic subdural hematoma recurrenceDual-energy CT imagingChronic subdural hematoma membranesDisease recurrenceArtery embolizationEmbolization treatmentRecurrence rateSurgical managementRadiographic biomarkersSurgical planningHematomaCT imagesRecurrenceNeurosurgical diseasesEmbolizationNarrative reviewTreatmentThrombectomy vs Medical Management for Posterior Cerebral Artery Stroke: Systematic Review, Meta-Analysis, and Real-World Data.
Chen H, Khunte M, Colasurdo M, Malhotra A, Gandhi D. Thrombectomy vs Medical Management for Posterior Cerebral Artery Stroke: Systematic Review, Meta-Analysis, and Real-World Data. Neurology 2024, 102: e209315. PMID: 38626383, PMCID: PMC11175628, DOI: 10.1212/wnl.0000000000209315.Peer-Reviewed Original ResearchConceptsSymptomatic intracranial hemorrhagePosterior cerebral arteryAssociated with higher oddsNational Inpatient SampleEndovascular thrombectomyHigher oddsMedical managementCohort studyFunctional independencePosterior cerebral artery strokeSafety of endovascular thrombectomyOdds of symptomatic intracranial hemorrhageAssociated with significantly higher ratesOxford Centre for Evidence-Based Medicine criteriaRates of in-hospital mortalityCentre for Evidence-Based Medicine criteriaMeta-analysisRate of ICHAssociated with different oddsHigher odds of deathRate of subarachnoid hemorrhageIn-hospital mortalityAssociated with lower ratesClass III evidenceLevel of evidenceFinancial Conflicts of Interest Among Physician Authors of ACR Appropriateness Criteria
Futela D, Khunte M, Bajaj S, Lee C, Tegtmeyer K, Payabvash S, Gandhi D, Malhotra A. Financial Conflicts of Interest Among Physician Authors of ACR Appropriateness Criteria. Academic Radiology 2024, 31: 2562-2566. PMID: 38538510, DOI: 10.1016/j.acra.2024.02.038.Peer-Reviewed Original ResearchACR-ACFinancial disclosureOpen Payments databaseACR Appropriateness CriteriaIndustry paymentsPhysician authorityAppropriateness CriteriaImaging guidelinesRadiology guidelinesUnique authorsUS authoritiesPayment reportsUS-based authorsFinancial relationshipsPayment categoriesFinancial conflictsPaymentDisclosurePayments DatabasePayment valueAccuracy of Financial Disclosures in Radiology Journals
Futela D, Khunte M, Bajaj S, Payabvash S, Gandhi D, Wintermark M, Malhotra A. Accuracy of Financial Disclosures in Radiology Journals. Journal Of The American College Of Radiology 2024 PMID: 38527639, DOI: 10.1016/j.jacr.2024.01.027.Peer-Reviewed Original ResearchFinancial disclosureRadiology journalsNon-disclosure ratesIndustry relationshipsDisclosureFinancial relationshipsPaymentPayment categoriesUS-based authorsIndustryUnique authorsOpen Payments databaseUS authoritiesMedian total amountPayment reportsAccuracyIndustry paymentsAuthorshipPhysician authorityOwnershipRelationshipSelf-disclosureAuthorsResearchJournalsSex Discrepancies in the Population Incidence of Stroke and Hemorrhage Related to Atrial Fibrillation or Flutter
Khunte M, Chen H, Colasurdo M, Chaturvedi S, Malhotra A, Gandhi D. Sex Discrepancies in the Population Incidence of Stroke and Hemorrhage Related to Atrial Fibrillation or Flutter. Cerebrovascular Diseases 2024, 1-6. PMID: 38432203, DOI: 10.1159/000538108.Peer-Reviewed Original ResearchAF-related ischemic strokeIschemic strokeAssociated with higher stroke riskIschemic stroke hospitalizationsRisk factorsAF-related strokeICD-10 codesRisk of hospitalizationVascular risk factorsRates of anticoagulant useHigher stroke riskIncidence of hospitalizationNational Inpatient SampleHigher stroke severityUnited States Census BureauIncidence of strokeAtrial fibrillationPatient demographic informationStroke hospitalizationsStroke characteristicsRelative riskICD-10Population incidenceRates of large vessel occlusionsRisk of morbidityClinical Applications of Dual‐Energy Computed Tomography for Acute Ischemic Stroke
Chen H, Bodanapally U, Colasurdo M, Malhotra A, Gandhi D. Clinical Applications of Dual‐Energy Computed Tomography for Acute Ischemic Stroke. Stroke Vascular And Interventional Neurology 2024, 4 DOI: 10.1161/svin.123.001193.Peer-Reviewed Original ResearchDual-energy computed tomographyAcute ischemic strokePostinterventional managementIschemic strokeDual-energyClinical applicationPredicting hemorrhagic transformationContext of acute ischemic strokeDiagnostic challengePatient selectionEarly cerebral ischemiaHemorrhagic transformationRecanalization therapyComputed tomographyClinical evidenceDiagnostic accuracyTreatment strategiesAcute stroke triageVascular lesionsNeurological disabilityCerebral ischemiaDiagnostic imagingTomographyStroke triageNarrative reviewRadiomics-Based Prediction of Collateral Status from CT Angiography of Patients Following a Large Vessel Occlusion Stroke
Avery E, Abou-Karam A, Abi-Fadel S, Behland J, Mak A, Haider S, Zeevi T, Sanelli P, Filippi C, Malhotra A, Matouk C, Falcone G, Petersen N, Sansing L, Sheth K, Payabvash S. Radiomics-Based Prediction of Collateral Status from CT Angiography of Patients Following a Large Vessel Occlusion Stroke. Diagnostics 2024, 14: 485. PMID: 38472957, PMCID: PMC10930945, DOI: 10.3390/diagnostics14050485.Peer-Reviewed Original ResearchCollateral statusCollateral scoreLarge vessel occlusionAcute LVO strokeRadiomics modelTest cohortCT angiography of patientsAdmission computed tomography angiographyAnterior circulation territoryAngiography of patientsLong-term outcomesReceiver operating characteristic areaRadiomics-based predictionCollateral arterial circulationOperating characteristics areaAdmission CTACirculation territoryCT angiographyClinical outcomesRadiomic featuresTreatment triageOcclusion strokeVessel occlusionPatientsArterial circulationUncertainty-aware deep-learning model for prediction of supratentorial hematoma expansion from admission non-contrast head computed tomography scan
Tran A, Zeevi T, Haider S, Abou Karam G, Berson E, Tharmaseelan H, Qureshi A, Sanelli P, Werring D, Malhotra A, Petersen N, de Havenon A, Falcone G, Sheth K, Payabvash S. Uncertainty-aware deep-learning model for prediction of supratentorial hematoma expansion from admission non-contrast head computed tomography scan. Npj Digital Medicine 2024, 7: 26. PMID: 38321131, PMCID: PMC10847454, DOI: 10.1038/s41746-024-01007-w.Peer-Reviewed Original ResearchDeep learning modelsHematoma expansionIntracerebral hemorrhageICH expansionComputed tomographyNon-contrast head CTNon-contrast head computed tomographyHigh risk of HEHead computed tomographyHigh-confidence predictionsRisk of HENon-contrast headReceiver operating characteristic areaModifiable risk factorsMonte Carlo dropoutOperating characteristics areaPotential treatment targetHead CTVisual markersIdentified patientsAutomated deep learning modelDataset of patientsRisk factorsHigh riskPatientsTime-Dependent Changes in Hematoma Expansion Rate after Supratentorial Intracerebral Hemorrhage and Its Relationship with Neurological Deterioration and Functional Outcome
Karam G, Chen M, Zeevi D, Harms B, Torres-Lopez V, Rivier C, Malhotra A, de Havenon A, Falcone G, Sheth K, Payabvash S. Time-Dependent Changes in Hematoma Expansion Rate after Supratentorial Intracerebral Hemorrhage and Its Relationship with Neurological Deterioration and Functional Outcome. Diagnostics 2024, 14: 308. PMID: 38337824, PMCID: PMC10855868, DOI: 10.3390/diagnostics14030308.Peer-Reviewed Original ResearchPredictors of NDSupratentorial intracerebral hemorrhageHematoma expansionIntracerebral hemorrhageNeurological deteriorationPoor outcomeNIH Stroke ScalePost-ICHFunctional outcomesMild symptomsHematoma expansion ratesIntracerebral hemorrhage onsetAssociation of HEModifiable risk factorsGlasgow Coma ScaleBaseline CTHematoma growthConsecutive patientsHead CTSCAN-3Follow-upRate of HEComa ScaleRisk factorsHematomaLetter to the Editor Re “Rethinking Cervical Spine Clearance in Obtunded Trauma Patients: An Updated Systematic Review and Meta-Analysis”.
Malhotra A, Wu X, Khunte M. Letter to the Editor Re “Rethinking Cervical Spine Clearance in Obtunded Trauma Patients: An Updated Systematic Review and Meta-Analysis”. Injury 2024, 55: 111359. PMID: 38262333, DOI: 10.1016/j.injury.2024.111359.Peer-Reviewed Original ResearchTime-driven activity-based costing (TDABC) of direct-to-angiography pathway for acute ischemic stroke patients with suspected large vessel occlusion
Sangha K, White T, Boltyenkov A, Bastani M, Sanmartin M, Katz J, Malhotra A, Rula E, Naidich J, Sanelli P. Time-driven activity-based costing (TDABC) of direct-to-angiography pathway for acute ischemic stroke patients with suspected large vessel occlusion. Journal Of Stroke And Cerebrovascular Diseases 2024, 33: 107516. PMID: 38183964, DOI: 10.1016/j.jstrokecerebrovasdis.2023.107516.Peer-Reviewed Original ResearchAcute ischemic strokeEndovascular treatmentAcute ischemic stroke patientsAppropriate patient selection criteriaNovel care pathwayIschemic stroke patientsLarge vessel occlusionPatient selection criteriaInstitutional patient databaseTime-driven activity-based costingEligible patientsAnterior circulationIschemic strokeClinical outcomesPatient factorsStroke patientsAIS patientsVessel occlusionCare pathwayPatient costsMain cost driversPatientsPatient databaseAngiography suiteCT pathwayIndustry Payments to Physicians in the United States From 2017 to 2021 and the Impact of the COVID-19 Pandemic
Khunte M, Zhong A, Lee C, Wu X, Gandhi D, Malhotra A. Industry Payments to Physicians in the United States From 2017 to 2021 and the Impact of the COVID-19 Pandemic. Mayo Clinic Proceedings 2024, 99: 338-340. PMID: 38189685, DOI: 10.1016/j.mayocp.2023.11.009.Peer-Reviewed Original ResearchPeri-hematomal edema shape features related to 3-month outcome in acute supratentorial intracerebral hemorrhage
Dierksen F, Tran A, Zeevi T, Maier I, Qureshi A, Sanelli P, Werring D, Malhotra A, Falcone G, Sheth K, Payabvash S. Peri-hematomal edema shape features related to 3-month outcome in acute supratentorial intracerebral hemorrhage. European Stroke Journal 2024, 9: 383-390. PMID: 38179883, DOI: 10.1177/23969873231223814.Peer-Reviewed Original ResearchNIH Stroke ScaleGlasgow Coma ScaleAssociation of baselineIntracerebral hemorrhagePerihematomal edemaHematoma volumeAcute supratentorial intracerebral hemorrhageNon-traumatic intracerebral hemorrhageSecondary brain injuryAcute ICH patientsIndependent prognostic factorSupratentorial intracerebral hemorrhageAdmission NIH Stroke ScalePotential treatment targetRankin scoreStroke ScaleIndependent predictorsPatient agePrognostic factorsComa ScaleMultivariable analysisICH patientsPrognostic valueBrain injuryFavorable outcome
2023
Early brain microstructural development among preterm infants requiring caesarean section versus those delivered vaginally
Bobba P, Weber C, Malhotra A, Bahtiyar M, Copel J, Taylor S, Ment L, Payabvash S. Early brain microstructural development among preterm infants requiring caesarean section versus those delivered vaginally. Scientific Reports 2023, 13: 21514. PMID: 38057452, PMCID: PMC10700578, DOI: 10.1038/s41598-023-48963-z.Peer-Reviewed Original ResearchRe: “ACR Appropriateness Criteria® Headache: 2022 Update”
Malhotra A, Wu X, Khunte M, Rao B. Re: “ACR Appropriateness Criteria® Headache: 2022 Update”. Journal Of The American College Of Radiology 2023, 21: 697. PMID: 37984769, DOI: 10.1016/j.jacr.2023.07.034.Peer-Reviewed Original ResearchComment on Roman-Filip et al. Non-Aneurysmal Perimesencephalic Subarachnoid Hemorrhage: A Literature Review. Diagnostics 2023, 13, 1195
Malhotra A. Comment on Roman-Filip et al. Non-Aneurysmal Perimesencephalic Subarachnoid Hemorrhage: A Literature Review. Diagnostics 2023, 13, 1195. Diagnostics 2023, 13: 3463. PMID: 37998599, PMCID: PMC10670416, DOI: 10.3390/diagnostics13223463.Peer-Reviewed Original Research