2023
Intravenous thrombolysis prior to endovascular thrombectomy in elderly stroke patients: An analysis of the National Inpatient Sample database
Chen H, Khunte M, Colasurdo M, Malhotra A, Gandhi D. Intravenous thrombolysis prior to endovascular thrombectomy in elderly stroke patients: An analysis of the National Inpatient Sample database. Journal Of The Neurological Sciences 2023, 454: 120842. PMID: 37856997, DOI: 10.1016/j.jns.2023.120842.Peer-Reviewed Original ResearchMeSH KeywordsAgedBrain IschemiaCross-Sectional StudiesEndovascular ProceduresFibrinolytic AgentsHumansInpatientsStrokeThrombectomyThrombolytic TherapyTreatment OutcomeConceptsNational Inpatient Sample databaseHospital mortalityHemorrhagic complicationsIntravenous thrombolysisEndovascular thrombectomyEVT patientsIVT treatmentThrombectomy centreElderly patientsMultivariable logistic regression modelSample databaseStroke risk factorsElderly stroke patientsCross-sectional studyLarge-scale cross-sectional studyOutcomes of interestHigh rateLogistic regression modelsPatients 80Medical comorbiditiesOnly patientsPatient demographicsStroke etiologyThrombolytic treatmentHemorrhagic riskAssociation of Body Mass Index and Waist Circumference With Imaging Metrics of Brain Integrity and Functional Connectivity in Children Aged 9 to 10 Years in the US, 2016-2018
Kaltenhauser S, Weber C, Lin H, Mozayan A, Malhotra A, Constable R, Acosta J, Falcone G, Taylor S, Ment L, Sheth K, Payabvash S. Association of Body Mass Index and Waist Circumference With Imaging Metrics of Brain Integrity and Functional Connectivity in Children Aged 9 to 10 Years in the US, 2016-2018. JAMA Network Open 2023, 6: e2314193. PMID: 37200030, PMCID: PMC10196880, DOI: 10.1001/jamanetworkopen.2023.14193.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBenchmarkingBody Mass IndexBrainChildCross-Sectional StudiesFemaleHumansMaleNeuroimagingPediatric ObesityWaist CircumferenceWeight GainConceptsBody mass indexHigher body mass indexWaist circumferenceBMI z-scoreCross-sectional studyBrain healthCross-sectional analysisFunctional connectivityMass indexMean ageInterval developmentCorpus callosumAssociation of BMIHigher baseline body mass indexBaseline cross-sectional analysisBaseline body mass indexBrain integrityResting-state functional connectivityLongitudinal analysisFuture treatment trialsABCD studyLower microstructural integrityCognitive Development StudyAdolescent Brain Cognitive Development (ABCD) studyCardiovascular implicationsClinical criteria to exclude acute vascular pathology on CT angiogram in patients with dizziness
Tu L, Malhotra A, Venkatesh A, Taylor R, Sheth K, Yaesoubi R, Forman H, Sureshanand S, Navaratnam D. Clinical criteria to exclude acute vascular pathology on CT angiogram in patients with dizziness. PLOS ONE 2023, 18: e0280752. PMID: 36893103, PMCID: PMC9997874, DOI: 10.1371/journal.pone.0280752.Peer-Reviewed Original ResearchMeSH KeywordsAdultAngiographyCross-Sectional StudiesDizzinessEmergency Service, HospitalHumansStrokeTomography, X-Ray ComputedVertigoConceptsAcute vascular pathologyEmergency departmentVascular pathologyNegative predictive valueDizzy patientsStroke codeCTA headPredictive valueAdult ED encountersTransient ischemic attackHalf of patientsLong-term smokersLarge vessel occlusionCoronary artery diseasePast medical historySeparate validation cohortCross-sectional analysisIschemic attackAnalysis cohortArterial dissectionArtery diseaseClinical factorsED encountersMedication useChief complaint
2022
Associations of Osteoarthritis With Thrombectomy Utilization and Outcomes for Large Vessel Acute Ischemic Stroke
Chen H, Khunte M, Colasurdo M, Jindal G, Malhotra A, Gandhi D, Chaturvedi S. Associations of Osteoarthritis With Thrombectomy Utilization and Outcomes for Large Vessel Acute Ischemic Stroke. Stroke 2022, 54: 518-526. PMID: 36541211, DOI: 10.1161/strokeaha.122.041749.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrain IschemiaCross-Sectional StudiesEndovascular ProceduresHumansIschemic StrokeOsteoarthritisStrokeThrombectomyTreatment OutcomeConceptsMultivariable logistic regression modelEndovascular thrombectomyAssociation of osteoarthritisLogistic regression modelsHospital mortalityMedical comorbiditiesIschemic strokeRisk factorsLower oddsLarge vessel acute ischemic strokeNational Inpatient Sample databaseMultivariable logistic regression analysisLarge-vessel ischemic strokeIntravenous thrombolysis treatmentStroke risk factorsAcute ischemic strokeIschemic stroke patientsPresence of osteoarthritisCause of disabilityCross-sectional studyLogistic regression analysisPatient selection practicesLarge-scale cross-sectional studyDirect risk factorEVT treatment