Pipeline Endovascular Device vs Stent-Assisted Coiling in Small Unruptured Aneurysms: A Cost-Effectiveness Analysis.
Malhotra A, Wu X, Brinjikji W, Miller T, Matouk CC, Sanelli P, Gandhi D. Pipeline Endovascular Device vs Stent-Assisted Coiling in Small Unruptured Aneurysms: A Cost-Effectiveness Analysis. Neurosurgery 2019, 85: e1010-e1019. PMID: 31329957, DOI: 10.1093/neuros/nyz130.Peer-Reviewed Original ResearchConceptsStent-assisted coilingProbabilistic sensitivity analysesRetreatment rateUnruptured aneurysmsUnruptured anterior circulation aneurysmsPipeline endovascular deviceAnterior circulation aneurysmsLong-term outcomesAneurysm recurrence rateOne-way sensitivity analysesPipeline Embolization DeviceSmall unruptured anterior circulation aneurysmsSmall unruptured aneurysmsSensitivity analysisBetter health outcomesDecision-analytical studyCost-effective relativeCost-effectiveness analysisRecurrence rateStent coilingBase case calculationAneurysm sizeEmbolization DeviceAneurysm recurrenceHealth outcomesComparative effectiveness analysis of Pipeline device versus coiling in unruptured aneurysms smaller than 10 mm.
Malhotra A, Wu X, Miller T, Matouk CC, Sanelli P, Gandhi D. Comparative effectiveness analysis of Pipeline device versus coiling in unruptured aneurysms smaller than 10 mm. Journal Of Neurosurgery 2019, 132: 42-50. PMID: 30641830, DOI: 10.3171/2018.8.jns181080.Peer-Reviewed Original ResearchConceptsPipeline Embolization DeviceStent-assisted coilingRetreatment rateSmall unruptured aneurysmsComparative effectiveness analysisProbabilistic sensitivity analysesUnruptured aneurysmsEndovascular coilingHealth benefitsUse of PEDHigher health benefitsRate of recurrenceFavorable treatment strategyDecision-analytical studyStent-assisted techniquePED placementTreatment modalitiesEffectiveness analysisTreatment strategiesSmall aneurysmsEmbolization DeviceSimple coilingOutcome riskAneurysmsRetreatment