Progressive T1 Shortening of the Dentate Nucleus in Patients With Multiple Sclerosis: Result of Multiple Administrations of Linear Gadolinium Contrast Agents Versus Intrinsic Disease.
Malhotra A, LeSar B, Wu X, Durand D, Das N, Anzai Y, Sanelli P. Progressive T1 Shortening of the Dentate Nucleus in Patients With Multiple Sclerosis: Result of Multiple Administrations of Linear Gadolinium Contrast Agents Versus Intrinsic Disease. American Journal Of Roentgenology 2018, 211: 1099-1105. PMID: 30160975, DOI: 10.2214/ajr.17.19155.Peer-Reviewed Original ResearchConceptsMacrocyclic agent gadobutrolMultiple sclerosisGlobus pallidusDentate nucleusGadolinium-based contrast agentsGadopentetate dimeglumineIntrinsic diseaseContrast injectionMultiple administrationsRelapsing-remitting multiple sclerosisMultiple contrast injectionsSubsequent MRI studiesUnenhanced T1-weighted imagesT1-weighted imagesIntrinsic T1 hyperintensityPons SI ratioContrast agent administrationRetrospective reviewMore dosesT1 hyperintensitySignal intensity ratioContrast agentsGadolinium contrastMRI studiesPatients