2019
Control of Bacterial Virulence through the Peptide Signature of the Habitat
Krypotou E, Scortti M, Grundström C, Oelker M, Luisi B, Sauer-Eriksson A, Vázquez-Boland J. Control of Bacterial Virulence through the Peptide Signature of the Habitat. Cell Reports 2019, 26: 1815-1827.e5. PMID: 30759392, PMCID: PMC6389498, DOI: 10.1016/j.celrep.2019.01.073.Peer-Reviewed Original ResearchMeSH KeywordsBacterial ProteinsEcosystemGene Expression Regulation, BacterialHumansListeria monocytogenesMutationPeptidesVirulenceConceptsBacterial virulenceControl of bacterial virulenceFacultative intracellular bacterium Listeria monocytogenesOpp transport systemIntracellular bacterium Listeria monocytogenesBacterium Listeria monocytogenesGSH-binding siteVirulence programCo-crystallization studiesNutritional peptidesPrfAGenetic screeningTranscriptional activityOrganic N sourcesVirulenceNon-cysteine-containing peptidesSteric blockadeHost entryRegulation mechanismBinding sitesPeptide signaturesActive peptidesPeptideN sourcesOligopeptides
2017
Listeria Placental Infection
Vázquez-Boland J, Krypotou E, Scortti M. Listeria Placental Infection. MBio 2017, 8: 10.1128/mbio.00949-17. PMID: 28655824, PMCID: PMC5487735, DOI: 10.1128/mbio.00949-17.Peer-Reviewed Original ResearchMeSH KeywordsFemaleHumansInfectious Disease Transmission, VerticalListeria monocytogenesListeriosisPlacentaPregnancyConceptsCongenital neonatal infectionsAdverse pregnancy outcomesAbsence of overt illnessSystemic bacterial infectionNonhuman primate modelFetal complicationsCausative agent of listeriosisNeonatal infectionPreterm birthPregnancy outcomesPregnant womenFood-borne infectionsBacterial infectionsPrimate modelTransplacental infectionInfectionOvert illnessMedical interventionsCausative agentListeriosisComplicationsMiscarriageStillbirthPathophysiologyBirth