2022
The extent to which geography explains one of trauma’s troubling trends: Insurance-based differences in appropriate interfacility transfer
Zogg CK, Schuster KM, Maung AA, Davis KA. The extent to which geography explains one of trauma’s troubling trends: Insurance-based differences in appropriate interfacility transfer. Journal Of Trauma And Acute Care Surgery 2022, 93: 686-694. PMID: 35293375, PMCID: PMC9470786, DOI: 10.1097/ta.0000000000003605.Peer-Reviewed Original ResearchConceptsNontrauma centersEmergency departmentMajor injuriesTrauma centerSignificant geographic variationInsurance-based differencesRisk-adjusted oddsLarge trauma centersNeighborhood socioeconomic disadvantageHierarchical logistic regressionInsured adultsTransfer patientsInsurance statusInterfacility transferStratified analysisED claimsUninsured adultsLevel IIISecondary objectiveTriage patternsDeprived populationsLogistic regressionInjurySocioeconomic disadvantageAdmission differences
2021
Anticoagulation Is Associated with Increased Mortality in Splenic Injuries
Bhattacharya B, Becher RD, Schuster KM, Davis KA, Maung AA. Anticoagulation Is Associated with Increased Mortality in Splenic Injuries. Journal Of Surgical Research 2021, 266: 1-5. PMID: 33975026, DOI: 10.1016/j.jss.2021.04.002.Peer-Reviewed Original ResearchConceptsNon-ACS patientsSplenic injuryAC patientsMultivariable binary logistic regressionIndependent risk factorEffect of anticoagulationInjury Severity ScoreUnits of RBCsBinary logistic regressionHospital courseMedian LOSIncreased MortalitySeverity scoreRisk factorsWorse outcomesAnticoagulationSplenic surgeryAC groupPatientsHigh mortalityInjuryLogistic regressionMortalitySerious injuriesAngiography
2020
The effect of anticoagulation on outcomes after liver and spleen injuries: A research consortium of New England centers for trauma (ReCONECT) study
Bhattacharya B, Askari R, Davis KA, Dorfman J, Eid AI, Elsharkawy AE, Kasotakis G, Mackey S, Odom S, Okafor BU, Rosenblatt M, Ruditsky A, Velmahos G, Maung AA. The effect of anticoagulation on outcomes after liver and spleen injuries: A research consortium of New England centers for trauma (ReCONECT) study. Injury 2020, 51: 1994-1998. PMID: 32482426, DOI: 10.1016/j.injury.2020.05.002.Peer-Reviewed Original ResearchConceptsNon-ACS patientsEffect of anticoagulationNon-operative managementSpleen injurySplenic injuryLiver injuryInitial non-operative managementSignificant differencesUse of anticoagulationBlood product transfusionMulticenter retrospective studyAC drugsMore PRBCsInjury gradeProduct transfusionCommon indicationAC patientsAtrial fibrillationRetrospective studyAnticoagulationSolid organsPatientsInjuryStudy periodLiver
2013
Role of fibrinogen in massive injury.
Maung AA, Kaplan LJ. Role of fibrinogen in massive injury. Minerva Anestesiologica 2013, 80: 89-95. PMID: 23857437.Peer-Reviewed Original ResearchConceptsRole of fibrinogenTrauma associated coagulopathyAcute traumatic coagulopathyEffect of acidosisLow fibrinogen concentrationAssociated coagulopathyControl hemorrhageTraumatic coagulopathyMassive hemorrhageFactor consumptionRotational thromboelastometryHyperfibrinolysisTherapeutic interventionsCoagulopathyInjuryFibrinogen concentrationMassive injuryHemorrhageComplex cascadeHypofibrinogenemia
2012
Mechanical Ventilation After Injury
Maung AA, Kaplan LJ. Mechanical Ventilation After Injury. Journal Of Intensive Care Medicine 2012, 29: 128-137. PMID: 22956744, DOI: 10.1177/0885066612457339.Peer-Reviewed Original ResearchConceptsMechanical ventilationPrimary respiratory failureTraumatic brain injuryMultiple organ systemsImpact of injuryConcomitant tissue injuryRespiratory failureCritical illnessVentilator strategiesBronchopleural fistulaVentilator managementBrain injuryPhysiologic changesTissue injuryBlast injuryInjuryThermal injuryOrgan systemsPatientsMajor causeVentilationSpecial considerationFistulaIllness
2008
The Influence of Injury on Toll-Like Receptor Responses
Murphy T, Maung A, Paterson H, Lederer J. The Influence of Injury on Toll-Like Receptor Responses. 2008, 185-202. DOI: 10.1201/9781420043198-17.ChaptersToll-like receptorsToll-like receptor responsesAdaptive immune responsesInfluence of injuryStrong inflammatory responseInnate immune systemCommon microbial antigensSentinel receptorsTLR ligandsMicrobial antigensInflammatory responseViral antigensTissue injuryTLR responsesImmune responseCell injuryReceptor responsesImmune systemTissue damageInjury responseEndogenous factorsMicrobial ligandsInjuryInfectionIntracellular receptors