2017
Single-Cell Metabolomics by Mass Spectrometry for Drug Discovery: Moving Forward
K R, T W, SF N, AV W. Single-Cell Metabolomics by Mass Spectrometry for Drug Discovery: Moving Forward. Drug Designing Open Access 2017, 6: 1-5. DOI: 10.4172/2169-0138.1000149.Peer-Reviewed Original ResearchSingle-cell metabolomicsMolecular levelSingle-cell isolationCellular functionsCellular statesOmics approachesFunctional screenMetabolite poolsCell metabolomicsCellular interactionsBiological researchMass spectrometryCell sortingDrug discoveryMetabolomicsTandem mass spectrometryDrug developmentMetabolomics researchConcentrations of metabolitesEnvironmental influencesComprehensive understandingComprehensive informationSortingFuture prospectsCells
2002
Effects of hexamethylene diisocyanate exposure on human airway epithelial cells: in vitro cellular and molecular studies.
Wisnewski AV, Liu Q, Miller JJ, Magoski N, Redlich CA. Effects of hexamethylene diisocyanate exposure on human airway epithelial cells: in vitro cellular and molecular studies. Environmental Health Perspectives 2002, 110: 901-907. PMID: 12204825, PMCID: PMC1240990, DOI: 10.1289/ehp.02110901.Peer-Reviewed Original ResearchConceptsHuman airway epithelial cellsImmunofluorescence analysisAirway epithelial cellsEpithelial cellsThiol redox homeostasisThioredoxin reductase expressionCellular stressEpithelial cell lineSensitive genesMicroarray analysisNorthern analysisHexamethylene diisocyanate exposureGenesAirway epithelial cell lineMolecular levelMolecular studiesDihydrodiol dehydrogenaseReductase expressionHDI exposureSubcytotoxic concentrationsCell linesMessage levelsImportant sensorMRNA levelsCells