Effects of central and peripheral injections of apelin on fluid intake and cardiovascular parameters in rats
Mitra A, Katovich MJ, Mecca A, Rowland NE. Effects of central and peripheral injections of apelin on fluid intake and cardiovascular parameters in rats. Physiology & Behavior 2006, 89: 221-225. PMID: 16839572, DOI: 10.1016/j.physbeh.2006.06.006.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsApelinBlood PressureCarrier ProteinsDose-Response Relationship, DrugDrinkingInjections, IntravenousInjections, IntraventricularIntercellular Signaling Peptides and ProteinsMaleRatsRats, Sprague-DawleyWater-Electrolyte BalanceConceptsBlood pressureFluid intakeRole of apelinHypotensive actionPeripheral administrationAntidipsogenic effectPeripheral injectionSodium appetiteCardiovascular parametersSated ratsAngiotensin peptidesSprague-DawleyUnrestrained ratsApelinFluid homeostasisRatsDisparate effectsIntakeNovel peptideConsistent effectRobust effectPrevious studiesPeptidesAdministrationAppetite