2013
Utilizing a Cranial Window to Visualize the Middle Cerebral Artery During Endothelin-1 Induced Middle Cerebral Artery Occlusion
Regenhardt R, Ansari S, Azari H, Caldwell K, Mecca A. Utilizing a Cranial Window to Visualize the Middle Cerebral Artery During Endothelin-1 Induced Middle Cerebral Artery Occlusion. Journal Of Visualized Experiments 2013 DOI: 10.3791/50015-v.Peer-Reviewed Original ResearchUtilizing a cranial window to visualize the middle cerebral artery during endothelin-1 induced middle cerebral artery occlusion.
Regenhardt RW, Ansari S, Azari H, Caldwell KJ, Mecca AP. Utilizing a cranial window to visualize the middle cerebral artery during endothelin-1 induced middle cerebral artery occlusion. Journal Of Visualized Experiments 2013, e50015. PMID: 23463164, PMCID: PMC3605805, DOI: 10.3791/50015.Peer-Reviewed Original ResearchConceptsCranial windowEndothelin-1Cerebral arteryBrain parenchymaMiddle cerebral artery occlusion modelMiddle cerebral artery occlusionCerebral artery occlusionArtery occlusion modelMiddle cerebral arteryArtery occlusionIschemic strokeVasoconstricting peptideOcclusion modelVisualized vesselsLateral aspectTemporal boneArteryProximal portionRat cerebrumDuraVessel diameterCortical surfaceMCAOParietal boneParenchyma
2009
Efficacy of 3,5‐dibromo‐L‐phenylalanine in rat models of stroke, seizures and sensorimotor gating deficit
Cao W, Shah H, Glushakov A, Mecca A, Shi P, Sumners C, Seubert C, Martynyuk A. Efficacy of 3,5‐dibromo‐L‐phenylalanine in rat models of stroke, seizures and sensorimotor gating deficit. British Journal Of Pharmacology 2009, 158: 2005-2013. PMID: 20050189, PMCID: PMC2807662, DOI: 10.1111/j.1476-5381.2009.00498.x.Peer-Reviewed Original ResearchConceptsSensorimotor gating deficitsEndothelin-1Prepulse inhibitionMK-801Rat modelGating deficitsN-methyl-D-aspartate (NMDA) receptor antagonist dizocilpineDisruption of PPINeuropsychiatric disordersSelective glutamate receptor antagonistsArterial blood pressureMiddle cerebral arteryGlutamate receptor antagonistsSerious side effectsFurther clinical developmentPentylenetetrazole injectionBlood pressureCerebral arteryGlutamatergic activityGlutamatergic agentsIntracerebral injectionReceptor antagonistBrain damageBrain injuryNMDA antagonists