2022
Platelet FcγRIIa Expression in Ischemic Stroke: A Marker of Increased Platelet Reactivity
Schneider D, Honda T, Feldmann E, de Havenon A, Romano J, Nogueira R, Prabhakaran S, Mishra N, Beaman C, Hinman J, Commichau C, Callas P, Kaneko N, Morales J, Patel S, Sharma L, Kim S, Taatjes‐Sommer H, Liebeskind D. Platelet FcγRIIa Expression in Ischemic Stroke: A Marker of Increased Platelet Reactivity. Stroke Vascular And Interventional Neurology 2022, 2 DOI: 10.1161/svin.121.000201.Peer-Reviewed Original ResearchStroke/transient ischemic attackTransient ischemic attackRecent myocardial infarctionMyocardial infarctionPlatelet expressionFcγRIIa expressionNeurologic dysfunctionPlatelet reactivitySubsequent stroke/transient ischemic attacksSubsequent cardiovascular eventsEmbolic causesNonembolic causesPlatelet FcγRIIACardiovascular eventsIschemic attackIdentifies patientsIschemic strokeMethods PatientsDischarge diagnosisTreatment decisionsLower riskPatientsPlatelet activationFlow cytometryEmbolic
2021
Optimal Carotid Plaque Features on Computed Tomography Angiography Associated With Ischemic Stroke
Baradaran H, Eisenmenger LB, Hinckley PJ, de Havenon AH, Stoddard GJ, Treiman LS, Treiman GS, Parker DL, McNally J. Optimal Carotid Plaque Features on Computed Tomography Angiography Associated With Ischemic Stroke. Journal Of The American Heart Association 2021, 10: e019462. PMID: 33586471, PMCID: PMC8174260, DOI: 10.1161/jaha.120.019462.Peer-Reviewed Original ResearchConceptsMaximum soft plaque thicknessPlaque thicknessIntraluminal thrombusRim signIschemic strokeStroke sourcesPlaque featuresCarotid plaquesMultivariable Poisson regression modelsDiscriminatory valueRetrospective cross-sectional studyVulnerable carotid plaquesCross-sectional studyCarotid plaque featuresSpecific plaque featuresPoisson regression modelsStroke prediction modelsCarotid sourceCarotid stenosisCarotid CTAImaging featuresStenosis categoriesClinical markersTreatment decisionsStenosis
2017
Validation of the unruptured intracranial aneurysm treatment score: comparison with real-world cerebrovascular practice.
Ravindra VM, de Havenon A, Gooldy TC, Scoville J, Guan J, Couldwell WT, Taussky P, MacDonald JD, Schmidt RH, Park MS. Validation of the unruptured intracranial aneurysm treatment score: comparison with real-world cerebrovascular practice. Journal Of Neurosurgery 2017, 129: 100-106. PMID: 28984518, DOI: 10.3171/2017.4.jns17548.Peer-Reviewed Original ResearchConceptsUnruptured intracranial aneurysmsTreatment recommendationsUnruptured Intracranial Aneurysm Treatment ScoreReal-world treatment decisionsQuaternary academic medical centerPercentage of misclassificationReal-world cohortAcademic medical centerConsecutive patientsConservative managementCerebrovascular specialistsUIATSTreatment decisionsInclusion criteriaMedical CenterTreatment scoresPatientsRupture rateIntracranial aneurysmsScreening toolROC curveReal-world experienceCharacteristic curveTreatmentFurther validation