2022
CGRP, Migraine, and Brain MRI in CADASIL
Goldstein E, Gopal N, Badi M, Hodge D, de Havenon A, Glover P, Durham P, Huang J, Lin M, Baradaran H, Majersik J, Meschia J. CGRP, Migraine, and Brain MRI in CADASIL. The Neurologist 2022, 28: 231-236. PMID: 36729391, PMCID: PMC10277309, DOI: 10.1097/nrl.0000000000000478.Peer-Reviewed Original ResearchConceptsCalcitonin gene-related peptideMigraine-related disabilitySerum calcitonin gene-related peptideSerum CGRP levelsCGRP levelsBrain magnetic resonance imagingCerebral autosomal dominant arteriopathyGene-related peptideAutosomal dominant arteriopathyMagnetic resonance imagingCross-sectional analysisRadiographic associationRadiographic implicationsPrimary outcomeT2 hyperintensityCerebral microbleedsDisability ScaleSubcortical infarctsMigraine pathophysiologyVasoactive peptidesBrain MRIMigraine pathologyMigraineResonance imagingCADASIL
2016
Rare case of T-cell lymphoma presenting as acute myelopathy
Samara VC, de Havenon A. Rare case of T-cell lymphoma presenting as acute myelopathy. BMJ Case Reports 2016, 2016: bcr2016217944. PMID: 27769981, PMCID: PMC5093351, DOI: 10.1136/bcr-2016-217944.Peer-Reviewed Original ResearchConceptsT-cell lymphomaAcute myelopathySystemic T-cell lymphomaT-cell lymphoproliferative disorderExtensive T2 hyperintensityLower extremity paresthesiasLower extremity weaknessDiffuse contrast enhancementErythematous maculopapular rashT lymphocyte populationsBone marrow aspirateExtremity weaknessSystemic chemotherapyExtremity paresthesiasMaculopapular rashLymphoproliferative disordersRare presentationT2 hyperintensityPeripheral bloodSpinal MRIMarrow aspiratesRare caseCerebrospinal fluidMyelopathyChemotherapy
2015
Multicontrast High-Resolution Vessel Wall Magnetic Resonance Imaging and Its Value in Differentiating Intracranial Vasculopathic Processes
Mossa-Basha M, Hwang WD, De Havenon A, Hippe D, Balu N, Becker KJ, Tirschwell DT, Hatsukami T, Anzai Y, Yuan C. Multicontrast High-Resolution Vessel Wall Magnetic Resonance Imaging and Its Value in Differentiating Intracranial Vasculopathic Processes. Stroke 2015, 46: 1567-1573. PMID: 25953365, DOI: 10.1161/strokeaha.115.009037.Peer-Reviewed Original ResearchConceptsReversible cerebral vasoconstriction syndromeVessel wall magnetic resonance imagingCerebral vasoconstriction syndromeMagnetic resonance imagingT2 hyperintensityIntracranial vasculopathyResonance imagingWall thickeningPattern of enhancementCases of atherosclerosisIntracranial vascular diseaseT2 signal characteristicsExcellent inter-reader agreementInter-reader agreementVasculitic lesionsInvasive workupWall involvementStenotic lesionsVasculopathic processPostcontrast enhancementVascular diseaseDifferential diagnosisVasculopathyLesion typeSyndrome
2014
Posterior reversible encephalopathy syndrome with spinal cord involvement
de Havenon A, Joos Z, Longenecker L, Shah L, Ansari S, Digre K. Posterior reversible encephalopathy syndrome with spinal cord involvement. Neurology 2014, 83: 2002-2006. PMID: 25355822, DOI: 10.1212/wnl.0000000000001026.Peer-Reviewed Original ResearchConceptsSpinal cord involvementReversible encephalopathy syndromeSpinal cord lesionsCord involvementEncephalopathy syndromeCord lesionsCervicomedullary junctionT2 hyperintensityHypertensive retinopathySpinal cordGrade IV hypertensive retinopathyReversible posterior leukoencephalopathy syndromeSpinal cord T2 hyperintensityCase of PRESPosterior leukoencephalopathy syndromeSevere acute hypertensionCohort of patientsFavorable clinical courseCervical spine MRIPatient management decisionsAcute hypertensionAntihypertensive treatmentHypertensive encephalopathyLeukoencephalopathy syndromeEmpiric treatment