2023
Polygenic Susceptibility to Hypertension and Blood Pressure Control in Stroke Survivors
Acosta J, Both C, Demarais Z, Conlon C, Leasure A, Torres-Lopez V, de Havenon A, Petersen N, Gill T, Sansing L, Sheth K, Falcone G. Polygenic Susceptibility to Hypertension and Blood Pressure Control in Stroke Survivors. Neurology 2023, 100: e1587-e1597. PMID: 36690452, PMCID: PMC10103110, DOI: 10.1212/wnl.0000000000206763.Peer-Reviewed Original ResearchConceptsWorse BP controlUncontrolled blood pressureDiastolic blood pressureBlood pressureStroke survivorsPolygenic risk scoresBP controlPolygenic susceptibilityMean diastolic blood pressureMean systolic blood pressureStroke Prevention TrialBlood pressure controlSystolic blood pressureResistant hypertensionVascular eventsHemorrhagic strokePrevention trialsVitamin InterventionMultivariable modelRisk scoreGenetic predispositionPressure controlLogistic regressionSurvivorsHypertension
2021
Predicting neuroimaging eligibility for extended-window endovascular thrombectomy.
de Havenon A, Mickolio K, O'Donnell S, Stoddard G, McNally JS, Alexander M, Taussky P, Awad AW. Predicting neuroimaging eligibility for extended-window endovascular thrombectomy. Journal Of Neurosurgery 2021, 135: 1100-1104. PMID: 33636705, PMCID: PMC8387497, DOI: 10.3171/2020.8.jns20386.Peer-Reviewed Original ResearchLarge vessel occlusionAlberta Stroke Program Early CT ScoreTissue plasminogen activatorEndovascular thrombectomyC-statisticPatients 5Stroke patientsTreatment windowFurther patient careHealth Stroke ScaleIschemic stroke treatmentLarge patient registriesSecond outcomePatients 4.5Stroke ScaleAdvanced imaging toolsStroke treatmentSalvageable penumbraCT scorePatient eligibilityClinical variablesPatient RegistryMultivariable modelMR perfusionTreatment cutoff