Modelling anticoagulation and health-related quality of life in those with atrial fibrillation: a secondary analysis of AFFIRM
Stulberg E, Delic A, Zheutlin A, Steinberg B, Yaghi S, Sharma R, de Havenon A. Modelling anticoagulation and health-related quality of life in those with atrial fibrillation: a secondary analysis of AFFIRM. Clinical Research In Cardiology 2023, 113: 1200-1210. PMID: 37962572, DOI: 10.1007/s00392-023-02335-9.Peer-Reviewed Original ResearchHealth-related qualityTime-varying confoundingAtrial fibrillationTime-varying covariatesSecondary analysisSelection biasAssociation of anticoagulationAssociation of warfarinAtrial Fibrillation FollowAge-stratified analysisLife substudyWarfarin useBetter HRQoLPrimary endpointTrial qualityHigher HRQoLStudy baselineEffect modificationStratified analysisAnticoagulationHRQoLInverse probabilityFibrillationStudy periodTime pointsAssociation of Blood Pressure Variability With Death and Discharge Destination Among Critically Ill Patients With and Without Stroke
Stulberg E, Harris B, Zheutlin A, Delic A, Sheibani N, Anadani M, Yaghi S, Petersen N, de Havenon A. Association of Blood Pressure Variability With Death and Discharge Destination Among Critically Ill Patients With and Without Stroke. Neurology 2023, 101: e1145-e1157. PMID: 37487742, PMCID: PMC10513881, DOI: 10.1212/wnl.0000000000207599.Peer-Reviewed Original ResearchConceptsAverage real variabilityNonstroke patientsDischarge destinationHospital deathIschemic strokeIll patientsIllness severityWorse outcomesAdult intensive care unit patientsMinimum mean arterial pressureIntensive care unit patientsIntensive Care III databaseBlood pressure goalsAcute ischemic strokeMean arterial pressureBlood pressure variabilityCare unit patientsRisk of deathMedical Information MartUnit patientsArterial pressureIntracerebral hemorrhageSubarachnoid hemorrhageRisk factorsEffect modification