2023
Polygenic Susceptibility to Hypertension and Blood Pressure Control in Stroke Survivors
Acosta J, Both C, Demarais Z, Conlon C, Leasure A, Torres-Lopez V, de Havenon A, Petersen N, Gill T, Sansing L, Sheth K, Falcone G. Polygenic Susceptibility to Hypertension and Blood Pressure Control in Stroke Survivors. Neurology 2023, 100: e1587-e1597. PMID: 36690452, PMCID: PMC10103110, DOI: 10.1212/wnl.0000000000206763.Peer-Reviewed Original ResearchConceptsWorse BP controlUncontrolled blood pressureDiastolic blood pressureBlood pressureStroke survivorsPolygenic risk scoresBP controlPolygenic susceptibilityMean diastolic blood pressureMean systolic blood pressureStroke Prevention TrialBlood pressure controlSystolic blood pressureResistant hypertensionVascular eventsHemorrhagic strokePrevention trialsVitamin InterventionMultivariable modelRisk scoreGenetic predispositionPressure controlLogistic regressionSurvivorsHypertension
2021
Blood Pressure Management After Endovascular Thrombectomy
Peng TJ, Ortega-Gutiérrez S, de Havenon A, Petersen NH. Blood Pressure Management After Endovascular Thrombectomy. Frontiers In Neurology 2021, 12: 723461. PMID: 34539562, PMCID: PMC8446280, DOI: 10.3389/fneur.2021.723461.Peer-Reviewed Original ResearchEndovascular thrombectomyBlood pressureBP targetsAnterior circulation large vessel occlusion strokeImmediate post-stroke periodLower blood pressure targetsLarge vessel occlusion strokeAdequate BP targetsBlood pressure targetsOptimal hemodynamic managementOverall hemodynamic statusPost-stroke periodAcute stroke therapyBlood pressure managementDegree of reperfusionPotential neuroprotective strategiesIndividual patient factorsStandard of careBlood pressure optimizationNovel treatment strategiesWorse clinical recoveryBP controlKey observational studiesSuccessful reperfusionClinical recovery