2024
Causal and common risk pathways linking childhood maltreatment to later intimate partner violence victimization
Pezzoli P, Pingault J, Eley T, McCrory E, Viding E. Causal and common risk pathways linking childhood maltreatment to later intimate partner violence victimization. Molecular Psychiatry 2024, 1-11. PMID: 39488656, DOI: 10.1038/s41380-024-02813-0.Peer-Reviewed Original ResearchIntimate partner violence victimizationIntimate partner violenceChildhood maltreatmentTwins Early Development StudyPartner violence victimizationSmall-to-moderate rangeNonshared environmental influencesEnvironmental influencesEarly Development StudyPsychiatric risk factorsEffects of maltreatmentRetrospective self-reportsRetrospective self-reports of maltreatmentIndividual-level riskPartner violenceViolence victimizationDevelopment studiesMaltreatmentVictimsIntimate relationshipsGenetic influencesCo-twinQuantitative genetic methodsRisk pathwaysModerating effect
2022
Social thinning and stress generation after childhood maltreatment: a neurocognitive social transactional model of psychiatric vulnerability
McCrory E, Foulkes L, Viding E. Social thinning and stress generation after childhood maltreatment: a neurocognitive social transactional model of psychiatric vulnerability. The Lancet Psychiatry 2022, 9: 828-837. PMID: 35926524, DOI: 10.1016/s2215-0366(22)00202-4.Peer-Reviewed Original ResearchConceptsTransactional modelChildhood maltreatmentNeurocognitive alterationsPsychiatric disordersQuantity of relationshipsIndividual's social networkSocial functioningSocial architecturePsychiatric vulnerabilityMaltreatmentSocial environmentExtant evidencePsychiatric riskNeurocognitive sequelaeSocial processesStress generationSocial networksDisordersAltered reward and effort processing in children with maltreatment experience: a potential indicator of mental health vulnerability
Armbruster-Genç D, Valton V, Neil L, Vuong V, Freeman Z, Packer K, Kiffin M, Roiser J, Viding E, McCrory E. Altered reward and effort processing in children with maltreatment experience: a potential indicator of mental health vulnerability. Neuropsychopharmacology 2022, 47: 1063-1070. PMID: 35149765, PMCID: PMC8832084, DOI: 10.1038/s41386-022-01284-7.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingInternalizing symptomsHistory of maltreatmentAnterior cingulate cortexEffort processingEffort-based decision-making taskDecision-making taskEffort-based decisionElevated internalizing symptomsNon-maltreated childrenImpact of maltreatmentMental health vulnerabilitiesFuture internalizing symptomsNeural indicesACC activationAltered rewardBehavioral indicesMaltreatment experiencesLatent vulnerabilityCingulate cortexEffort sensitivityGroup differencesRewardMaltreatmentLongitudinal study
2021
Functional brain plasticity following childhood maltreatment: A longitudinal fMRI investigation of autobiographical memory processing.
Puetz V, Viding E, Maguire E, Mechelli A, Armbruster-Genç D, Sharp M, Rankin G, Gerin M, McCrory E. Functional brain plasticity following childhood maltreatment: A longitudinal fMRI investigation of autobiographical memory processing. Development And Psychopathology 2021, 35: 1382-1389. PMID: 34924093, DOI: 10.1017/s0954579421001292.Peer-Reviewed Original ResearchConceptsChildhood maltreatmentAutobiographical memory processingCortical midline structuresValenced cue wordsPotential developmental plasticityCue wordsMemory processingFMRI studyBOLD signal changesNeural functioningPsychological assessmentBrain networksMaltreatmentMidline structuresMaturational changesLongitudinal analysisProcessingSignal changesFMRIPsychopathologyRecallAdolescentsFunctioningWordsDevelopmental plasticityTrust and childhood maltreatment: evidence of bias in appraisal of unfamiliar faces
Neil L, Viding E, Armbruster‐Genc D, Lisi M, Mareschal I, Rankin G, Sharp M, Phillips H, Rapley J, Martin P, McCrory E. Trust and childhood maltreatment: evidence of bias in appraisal of unfamiliar faces. Journal Of Child Psychology And Psychiatry 2021, 63: 655-662. PMID: 34500497, DOI: 10.1111/jcpp.13503.Peer-Reviewed Original ResearchConceptsTrust processingUnfamiliar facesChildhood maltreatmentPoor social functioningMental health difficultiesMental health problemsFacial stimuliCognitive abilitiesTrust judgmentsTrust attributionTrustworthiness dimensionsCommunity-based sampleSocial service recordsSocial functioningMaltreatment experiencesHealth difficultiesChild maltreatmentMaltreatmentSocial bondsAtypical patternsPeersEvidence of biasChildrenSocioeconomic statusProcessingChild Maltreatment, Peer Victimization, and Mental Health: Neurocognitive Perspectives on the Cycle of Victimization
Goemans A, Viding E, McCrory E. Child Maltreatment, Peer Victimization, and Mental Health: Neurocognitive Perspectives on the Cycle of Victimization. Trauma Violence & Abuse 2021, 24: 530-548. PMID: 34355601, PMCID: PMC10009486, DOI: 10.1177/15248380211036393.Peer-Reviewed Original ResearchConceptsMental healthMental health careMental health outcomesAdverse childhood experiencesMental health vulnerabilitiesSystematic scoping reviewInpatient populationChild maltreatmentHealth outcomesGoogle ScholarHealth careNeurocognitive functioningPutative mechanismsRisk of revictimizationScoping ReviewHealth vulnerabilityChildrenNeurocognitive findingsPreventative modelAdditive effectChildhood experiencesRiskPeer victimizationHealthMaltreatment
2020
The case for a preventative approach to mental health: Childhood maltreatment, neuroimaging, and the theory of latent vulnerability
McCrory E. The case for a preventative approach to mental health: Childhood maltreatment, neuroimaging, and the theory of latent vulnerability. 2020, 175-189. DOI: 10.1093/med/9780198789697.003.0011.Peer-Reviewed Original ResearchPsychiatric disordersChildhood maltreatmentFuture psychiatric disordersMagnetic resonance imaging researchClinical studiesLatent vulnerabilityClinical approachFunctional magnetic resonance imaging (fMRI) researchEarly adverse environmentsAltered functioningMental healthDisordersPreventative approachMaltreatmentImaging research
2019
A review of childhood maltreatment, latent vulnerability and the brain: implications for clinical practice and prevention
Gerin M, Hanson E, Viding E, McCrory E. A review of childhood maltreatment, latent vulnerability and the brain: implications for clinical practice and prevention. Adoption & Fostering 2019, 43: 310-328. DOI: 10.1177/0308575919865356.Peer-Reviewed Original ResearchMental health problemsLatent vulnerabilityNeurocognitive alterationsChildhood maltreatmentFuture mental health problemsEarly adverse environmentsCommon mental health problemsEmotion regulationThreat processingExecutive controlNeurocognitive systemsHealth problemsPoor mental healthReward processingMaltreated childrenFunctional neuroimagingFuture psychopathologyChild maltreatmentMental healthMaltreatmentLong-term outcomesSuch experiencesFunctioningClinical implicationsChildrenGhosts in the Nursery: An Experimental Investigation of a Parent’s Own Maltreatment Experience, Attention to Infant Faces, and Dyadic Reciprocity
Thompson-Booth C, Viding E, Puetz VB, Rutherford HJV, Mayes LC, McCrory EJ. Ghosts in the Nursery: An Experimental Investigation of a Parent’s Own Maltreatment Experience, Attention to Infant Faces, and Dyadic Reciprocity. Emotion 2019, 19: 1093-1102. PMID: 30234333, DOI: 10.1037/emo0000464.Peer-Reviewed Original ResearchConceptsInfant facesChildhood maltreatmentAttentional processingDyadic reciprocityLower attentional biasVisual search taskAttentional biasEmotional cuesCognitive processingPreferential processingInfant affectParenting behaviorsInfant cuesSearch taskAn Experimental InvestigationCommunity sampleMaltreatment experiencesMaltreatmentPreferential biasOwn childrenCuesExploratory analysisProcessingFaceImportant implicationsNeurocognitive Adaptation and Mental Health Vulnerability Following Maltreatment: The Role of Social Functioning
McCrory E, Ogle J, Gerin M, Viding E. Neurocognitive Adaptation and Mental Health Vulnerability Following Maltreatment: The Role of Social Functioning. Child Maltreatment 2019, 24: 435-451. PMID: 30897955, DOI: 10.1177/1077559519830524.Peer-Reviewed Original ResearchConceptsSocial functioningEarly maltreatment experiencesMental health vulnerabilitiesMental health problemsNeurocognitive adaptationsEmotion regulationThreat processingStudy of childrenReward processingComputational psychiatryMental health disordersMaltreatment experiencesLatent vulnerabilityChildhood maltreatmentSocial supportFunctioningHealth disordersNeural functionMaltreatmentHealth vulnerabilityProcessingHealth problemsVulnerabilityKey findingsAdolescents
2017
Risk-taking, peer-influence and child maltreatment: A neurocognitive investigation
Hoffmann F, Puetz V, Viding E, Sethi A, Palmer A, McCrory E. Risk-taking, peer-influence and child maltreatment: A neurocognitive investigation. Social Cognitive And Affective Neuroscience 2017, 13: nsx124-. PMID: 29069467, PMCID: PMC5793726, DOI: 10.1093/scan/nsx124.Peer-Reviewed Original ResearchConceptsRight anterior insulaMT groupBalloon Analogue Risk TaskMore anxiety symptomsPsychiatric disordersAnterior insulaFuture psychopathologyAnxiety symptomsChildrenDifferential effectsNeural correlatesNeurocognitive investigationsRisk-taking behaviorPeer influenceChild maltreatmentRiskGroupNeural levelMaltreatmentRisk TaskSymptomsInsulaThe Neuroscience and Genetics of Childhood Maltreatment
McCrory E, Puetz V, Viding E. The Neuroscience and Genetics of Childhood Maltreatment. 2017, 187-194. DOI: 10.1002/9781119170235.ch22.Peer-Reviewed Original ResearchPost-traumatic stress disorderChildhood maltreatmentHigher cognitive abilitiesStudy of childrenCognitive abilitiesEmotional processesInter-hemispheric communicationBody of researchAspects of behaviorStress disorderPrefrontal cortexSmaller hippocampal volumesBrain functionMaltreatmentBrain structuresSubcortical regionsNeural structuresHippocampal volumeCorpus callosumHost of processesWhite matter structuresLargest white matter structureNumber of studiesMatter structuresEmotionsThe Neurobiology and Genetics of Childhood Maltreatment
McCrory E, Palmer A, Puetz V. The Neurobiology and Genetics of Childhood Maltreatment. 2017, 85-96. DOI: 10.1002/9781118976111.ch6.Peer-Reviewed Original ResearchChildhood maltreatmentMaladaptive outcomesMagnetic resonance imagingBrain structuresKey brain structuresEmotion processingStudy of childrenPoor physical healthMaltreatment experiencesPhysical healthRegulation processesBrain functionMaltreatmentIndividual's lifePsychiatric disordersResonance imagingClinical implicationsGenetic factorsOutcomesMemoryNeurobiologyFindingsChildrenProcessing
2015
Exploring the Relationship Between Childhood Maltreatment and Addiction: A Review of the Neurocognitive Evidence
Puetz V, McCrory E. Exploring the Relationship Between Childhood Maltreatment and Addiction: A Review of the Neurocognitive Evidence. Current Addiction Reports 2015, 2: 318-325. PMID: 26550550, PMCID: PMC4628081, DOI: 10.1007/s40429-015-0073-8.Peer-Reviewed Original ResearchSubstance use disordersChildhood maltreatmentSeverity of illnessSevere clinical presentationClinical presentationPsychiatric disordersUse disordersBrain structuresHistory of maltreatmentDisordersAdultsRiskExecutive functioningMaltreatmentAlterationsNeurocognitive systemsSalient stimuliLatent vulnerabilityIllnessRisk environmentImpairmentThe Link Between Child Abuse and Psychopathology: A Review of Neurobiological and Genetic Research
McCrory E, De Brito S, Viding E. The Link Between Child Abuse and Psychopathology: A Review of Neurobiological and Genetic Research. 2015, 265-276. DOI: 10.1201/b18768-22.Peer-Reviewed Original ResearchEarly adversityChildhood abuseRecent human researchAdrenal axis stress responseStudy of childrenAtypical developmentEarly seminal studiesBody of researchStudies of adultsRegional brain structureChild abuseEarly stressBrain structuresHuman researchLong-term consequencesAbusePsychopathologyAdversityHeightened riskMaltreatmentClinical implicationsPossible clinical implicationsResearch contextNeurobiologicalNeuroendocrine functionChild maltreatment
Danese A, McCrory E. Child maltreatment. 2015, 364-375. DOI: 10.1002/9781118381953.ch29.Peer-Reviewed Original ResearchPhysical health impairmentPrompt recognitionPrimary preventionInflammatory responseEffective treatmentChild maltreatmentMarked distressChronic stressBrain structuresHealth impairmentMental healthLevel of interventionEncouraging findingsImpairmentMaltreatmentSexual abuseAbuse experiencesSequelaeAcademic functioningEmotional maltreatmentPreventionThe theory of latent vulnerability: Reconceptualizing the link between childhood maltreatment and psychiatric disorder
McCrory E, Viding E. The theory of latent vulnerability: Reconceptualizing the link between childhood maltreatment and psychiatric disorder. Development And Psychopathology 2015, 27: 493-505. PMID: 25997767, DOI: 10.1017/s0954579415000115.Peer-Reviewed Original ResearchConceptsPsychiatric disordersMental health problemsLatent vulnerabilityPsychiatric riskHealth problemsClinical interventionsDisordersNeurocognitive domainsPrevention approachesChildhood maltreatmentIntervention opportunitiesRisk trajectoriesPsychiatry approachMemory processingInterventionThreat processingChildrenRiskVulnerable childrenMaltreatmentLong termLife spanRisk environmentMaltreating environmentDistinct Mechanisms Underlie Associations Between Forms of Childhood Maltreatment and Disruptive Nocturnal Behaviors
Cecil C, Viding E, McCrory E, Gregory A. Distinct Mechanisms Underlie Associations Between Forms of Childhood Maltreatment and Disruptive Nocturnal Behaviors. Developmental Neuropsychology 2015, 40: 181-199. PMID: 26151615, DOI: 10.1080/87565641.2014.983636.Peer-Reviewed Original ResearchConceptsDisruptive nocturnal behaviorsSexual abuseChildhood maltreatmentTrauma-related psychopathologyHigh-risk youthExecutive functionCommunity sampleEmotional abuseMaltreatment typesTime of assessmentMaltreatmentSleep disturbancesAbuseNocturnal behaviorSpecific contributionSpecific formPsychopathologyYouthAssociationBehaviorChildhoodDistinct mechanismsFindings
2011
The Neuroscience and Genetics of Childhood Maltreatment
McCrory E, De Brito S, Viding E. The Neuroscience and Genetics of Childhood Maltreatment. 2011, 121-125. DOI: 10.1002/9781119993971.ch20.Peer-Reviewed Original ResearchLater psychopathologyChildhood maltreatmentFunctional brain differencesIndividual differencesPsychological adaptationEmotional developmentNeurobiological circuitryAntisocial personality disorderEarly adversityNeurobiological mechanismsBrain differencesConduct disorderEnvironmental experiencesChildhood adversityChildren's riskPsychopathologyPersonality disorderAdversityMaltreatmentNeuroscienceDisordersAnxietyProtective genesDepressionChildrenThe Impact of Childhood Maltreatment: A Review of Neurobiological and Genetic Factors
McCrory E, De Brito S, Viding E. The Impact of Childhood Maltreatment: A Review of Neurobiological and Genetic Factors. Frontiers In Psychiatry 2011, 2: 48. PMID: 21847382, PMCID: PMC3148713, DOI: 10.3389/fpsyt.2011.00048.Peer-Reviewed Original ResearchChildhood maltreatmentFunctional brain differencesFunctional MRI studyAdrenal axis stress responseCare-giving experienceMagnetic resonance imaging studyResonance imaging studyAtypical developmentEmotional developmentAtypical activationNeurobiological correlatesAmygdala hyperactivityBrain differencesFrontal regionsPsychiatric vulnerabilityEnvironmental adversityBehavioral studiesChildhood historyInformation biasesMaltreatmentPreliminary evidenceSuch experiencesStructural MRINeuroendocrine findingsSignificant risk factors