2001
Toxicity of Antiviral Nucleoside Analogs and the Human Mitochondrial DNA Polymerase*
Johnson A, Ray A, Hanes J, Suo Z, Colacino J, Anderson K, Johnson K. Toxicity of Antiviral Nucleoside Analogs and the Human Mitochondrial DNA Polymerase*. Journal Of Biological Chemistry 2001, 276: 40847-40857. PMID: 11526116, DOI: 10.1074/jbc.m106743200.Peer-Reviewed Original Research
1996
Glucose metabolism distal to a critical coronary stenosis in a canine model of low-flow myocardial ischemia.
McNulty PH, Sinusas AJ, Shi CQ, Dione D, Young LH, Cline GC, Shulman GI. Glucose metabolism distal to a critical coronary stenosis in a canine model of low-flow myocardial ischemia. Journal Of Clinical Investigation 1996, 98: 62-69. PMID: 8690805, PMCID: PMC507401, DOI: 10.1172/jci118778.Peer-Reviewed Original ResearchConceptsLow-flow ischemiaCoronary stenosisIschemic myocardiumIschemic regionLow-flow myocardial ischemiaCritical coronary stenosisExogenous glucoseOxidative substrateMyocardial ischemiaIntact dogsGlucose metabolismNonischemic regionsClinical observationsCanine modelGlucose utilizationIschemiaBiochemical measurementsMyocardial regionsRate of incorporationIntracellular metabolismTricarboxylic acid cycle fluxStenosisMyocardiumGlucoseGlucose-derived pyruvate
1988
Human Keratinocytes Catabolize Thymidine
Schwartz P, Kugelman L, Coifman Y, Hough L, Milstone L. Human Keratinocytes Catabolize Thymidine. Journal Of Investigative Dermatology 1988, 90: 8-12. PMID: 3335793, DOI: 10.1111/1523-1747.ep12462412.Peer-Reviewed Original ResearchConceptsHuman keratinocytesHuman neonatal foreskinHuman neonatal foreskin keratinocytesNeonatal foreskin keratinocytesCutaneous diseaseSoluble extractsGuinea pigsNeonatal foreskinKeratinocyte proliferationForeskin keratinocytesStratified culturesRate of incorporationAdult skinRadioactive thymidineKeratinocytesThymidine analogueAmount of thymidineExogenous thymidineSpecies differencesThymidineHuman fibroblastsSkinCatabolismDifferent tissuesCulture medium
1985
Influence of Theophylline on Fetal Rat Lung Phosphatidylcholine Synthesis in vivo
Moya F, Gross I. Influence of Theophylline on Fetal Rat Lung Phosphatidylcholine Synthesis in vivo. Neonatology 1985, 8: 9-16. PMID: 3987490, DOI: 10.1159/000457017.Peer-Reviewed Original ResearchConceptsSerum levelsFetal lung surfactant productionInfluence of theophyllineLung tissue concentrationsElevated serum levelsDoses of theophyllineLung surfactant productionPhosphatidylcholine synthesisMaternal ratioPregnant ratsIntraperitoneal administrationTissue concentrationsRate of incorporationSurfactant productionTheophyllineVivoFetusesRatsAdministrationDoses
1984
The reaction of 16α‐hydroxyestrone with erythrocytes in vitro and in vivo
BUCALA R, FISHMAN J, CERAMI A. The reaction of 16α‐hydroxyestrone with erythrocytes in vitro and in vivo. The FEBS Journal 1984, 140: 593-598. PMID: 6723653, DOI: 10.1111/j.1432-1033.1984.tb08143.x.Peer-Reviewed Original ResearchConceptsMembrane proteinsCellular proteinsCell lifeRed cell lifeLysine residuesProteinCovalent adductsHydrophobic chromatographyAcid-precipitable radioactivityRate of incorporationStable covalent adductCellsReverse-phase high-pressure liquid chromatographyElevated levelsResiduesAdduct formationRed cellsElectrophoresisVitro
1982
Fetal lung in organ culture. IV. Supra-additive hormone interactions
Gross I, Wilson C. Fetal lung in organ culture. IV. Supra-additive hormone interactions. Journal Of Applied Physiology 1982, 52: 1420-1425. PMID: 6286561, DOI: 10.1152/jappl.1982.52.6.1420.Peer-Reviewed Original ResearchConceptsFetal lung maturationLung maturationSupra-additive interactionOrgan cultureCombination of dexamethasoneRate of incorporationFetal rat lungVivo animal studiesHormone administrationFetal lungAnimal studiesRat lungSupra-additive stimulationThyroid hormonesNM dexamethasoneDexamethasone concentrationsMaximal stimulationLungDexamethasoneNM triiodothyroninePulmonary surfactantSignificant increaseStimulationPrecursor incorporationCyclic monophosphate
1980
Fetal lung in organ culture. III. Comparison of dexamethasone, thyroxine, and methylxanthines
Gross I, Wilson C, Ingleson L, Brehier A, Rooney S. Fetal lung in organ culture. III. Comparison of dexamethasone, thyroxine, and methylxanthines. Journal Of Applied Physiology 1980, 48: 872-877. PMID: 7451297, DOI: 10.1152/jappl.1980.48.5.872.Peer-Reviewed Original ResearchConceptsFetal lungComparison of dexamethasoneLung glycogen contentSurfactant-associated phospholipidsFetal rat lungPercentage of radioactivityRat lungAminophyllineCholine-containing phospholipidsThyroxineGlycogen contentCholine incorporationLungCaffeine treatmentSignificant decreaseOrgan cultureRate of incorporationSignificant increaseLysolecithin acyltransferaseExposure of explantsCholinephosphate cytidylyltransferaseDexamethasoneDifferent effectsMembrane phospholipidsMethylxanthines
1979
Effects of betamethasone on phospholipid content, composition and biosynthesis in the fetal rabbit lung
Rooney S, Gobran L, Marino P, Maniscalco W, Gross I. Effects of betamethasone on phospholipid content, composition and biosynthesis in the fetal rabbit lung. Biochimica Et Biophysica Acta 1979, 572: 64-76. PMID: 216408, DOI: 10.1016/0005-2760(79)90200-5.Peer-Reviewed Original ResearchConceptsLung lavageFetal lung lavageFetal lung slicesAdministration of betamethasoneEffect of betamethasoneFetal lung maturationFetal rabbit lungPhosphatidylcholine/sphingomyelin ratioLung glycogenBetamethasone administrationLung maturationPregnant rabbitsDays gestationFetal lungLung slicesRabbit lungsStress-induced accelerationDirect administrationSphingomyelin ratioSurfactant phospholipidsBetamethasoneAdministrationRate of incorporationSurfactant productionLavage
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