2022
A stop-gain variant in BTNL9 is associated with atherogenic lipid profiles
Carlson J, Krishnan M, Rosenthal S, Russell E, Zhang J, Hawley N, Moors J, Cheng H, Dalbeth N, de Zoysa J, Watson H, Qasim M, Murphy R, Naseri T, Reupena M, Viali S, Stamp L, Tuitele J, Kershaw E, Deka R, McGarvey S, Merriman T, Weeks D, Minster R. A stop-gain variant in BTNL9 is associated with atherogenic lipid profiles. Human Genetics And Genomics Advances 2022, 4: 100155. PMID: 36340932, PMCID: PMC9630829, DOI: 10.1016/j.xhgg.2022.100155.Peer-Reviewed Original ResearchConceptsStop-gain variantUnique population historyFine-mapping analysisEuropean ancestry populationsGenetic architecturePolynesian populationsPopulation historyGenetic analysisAssociation studiesSuggestive associationPolynesian ancestryCurrent understandingEvidence of associationAmerican SamoaBiological foundationsVariantsGeneticsPopulationNew ZealandBTNL9Ancestry
2020
Genome-wide association studies in Samoans give insight into the genetic architecture of fasting serum lipid levels
Carlson JC, Weeks DE, Hawley NL, Sun G, Cheng H, Naseri T, Reupena M, Tuitele J, Deka R, McGarvey ST, Minster RL. Genome-wide association studies in Samoans give insight into the genetic architecture of fasting serum lipid levels. Journal Of Human Genetics 2020, 66: 111-121. PMID: 32759990, PMCID: PMC7785639, DOI: 10.1038/s10038-020-0816-9.Peer-Reviewed Original ResearchMeSH KeywordsAdultApolipoprotein A-IApolipoproteins ECholesterol Ester Transfer ProteinsCholesterol, HDLCholesterol, LDLCohort StudiesFastingFemaleGenetic MarkersGenome-Wide Association StudyHumansLipid MetabolismLipidsMaleMiddle AgedPolymorphism, Single NucleotideQuantitative Trait LociSamoaTriglyceridesConceptsGenome-wide association studiesGenetic architectureAssociation studiesGenome-wide significant associationDifferent association signalsUnique population historyPopulation bottlenecksLipid lociPopulation historyAssociation signalsSuggestive associationRab21Current understandingMGAT1Association of variantsReplication cohortLipidsBiological foundationsVariantsLociLow-density lipoproteinInsightsPopulationLipid levelsHigh-density lipoprotein
2015
Naturally rare versus newly rare: demographic inferences on two timescales inform conservation of Galápagos giant tortoises
Garrick R, Kajdacsi B, Russello M, Benavides E, Hyseni C, Gibbs J, Tapia W, Caccone A. Naturally rare versus newly rare: demographic inferences on two timescales inform conservation of Galápagos giant tortoises. Ecology And Evolution 2015, 5: 676-694. PMID: 25691990, PMCID: PMC4328771, DOI: 10.1002/ece3.1388.Peer-Reviewed Original ResearchGalápagos giant tortoisesDeep timescalesDemographic historyGiant tortoisesLocal effective population sizeLong-term population historyPopulation sizeMitochondrial control regionEffective population sizeAnalysis of genotypicLevel of variationShallow timescalesNuclear intronsRecent bottleneckGenetic bottleneckCensus sizeNeutral markersPhylogenetic informationIsland ageMicrosatellite lociDemographic inferenceGenetic estimatesControl regionPopulation historyConservation perspective
2012
Correction: Corrigendum: Reconstructing Native American population history
Reich D, Patterson N, Campbell D, Tandon A, Mazieres S, Ray N, Parra M, Rojas W, Duque C, Mesa N, García L, Triana O, Blair S, Maestre A, Dib J, Bravi C, Bailliet G, Corach D, Hünemeier T, Bortolini M, Salzano F, Petzl-Erler M, Acuña-Alonzo V, Aguilar-Salinas C, Canizales-Quinteros S, Tusié-Luna T, Riba L, Rodríguez-Cruz M, Lopez-Alarcón M, Coral-Vazquez R, Canto-Cetina T, Silva-Zolezzi I, Fernandez-Lopez J, Contreras A, Jimenez-Sanchez G, Gómez-Vázquez M, Molina J, Carracedo Á, Salas A, Gallo C, Poletti G, B.Witonsky D, Alkorta-Aranburu G, Sukernik R, Osipova L, Fedorova S, Vasquez R, Villena M, Moreau C, Barrantes R, Pauls D, Excoffier L, Bedoya G, Rothhammer F, Dugoujon J, Larrouy G, Klitz W, Labuda D, Kidd J, Kidd K, Di Rienzo A, Freimer N, Price A, Ruiz-Linares A. Correction: Corrigendum: Reconstructing Native American population history. Nature 2012, 491: 288-288. DOI: 10.1038/nature11667.Peer-Reviewed Original ResearchReconstructing Native American population history
Reich D, Patterson N, Campbell D, Tandon A, Mazieres S, Ray N, Parra MV, Rojas W, Duque C, Mesa N, García LF, Triana O, Blair S, Maestre A, Dib JC, Bravi CM, Bailliet G, Corach D, Hünemeier T, Bortolini MC, Salzano FM, Petzl-Erler ML, Acuña-Alonzo V, Aguilar-Salinas C, Canizales-Quinteros S, Tusié-Luna T, Riba L, Rodríguez-Cruz M, Lopez-Alarcón M, Coral-Vazquez R, Canto-Cetina T, Silva-Zolezzi I, Fernandez-Lopez JC, Contreras AV, Jimenez-Sanchez G, Gómez-Vázquez MJ, Molina J, Carracedo Á, Salas A, Gallo C, Poletti G, Witonsky DB, Alkorta-Aranburu G, Sukernik RI, Osipova L, Fedorova SA, Vasquez R, Villena M, Moreau C, Barrantes R, Pauls D, Excoffier L, Bedoya G, Rothhammer F, Dugoujon JM, Larrouy G, Klitz W, Labuda D, Kidd J, Kidd K, Di Rienzo A, Freimer NB, Price AL, Ruiz-Linares A. Reconstructing Native American population history. Nature 2012, 488: 370-374. PMID: 22801491, PMCID: PMC3615710, DOI: 10.1038/nature11258.Peer-Reviewed Original Research
2010
Inference of Population History by Coupling Exploratory and Model-Driven Phylogeographic Analyses
Garrick R, Caccone A, Sunnucks P. Inference of Population History by Coupling Exploratory and Model-Driven Phylogeographic Analyses. International Journal Of Molecular Sciences 2010, 11: 1190-1227. PMID: 20480016, PMCID: PMC2871112, DOI: 10.3390/ijms11041190.Peer-Reviewed Original ResearchConceptsPhylogeographic analysisGene treesGenetic diversityConservation managementPopulation historyDNA sequencesGenetic datasetsGenetic dataCladistic analysisHistorical inferencesPopulation processesTemporal concordanceSynergistic interactionDiversitySpeciationSpatial distributionSequenceGeographic contextTrees
2005
Characterization of microsatellite loci for the Amazonian rummy‐nose tetra, Hemigrammus bleheri (Teleostei, Characidae)
BEHEREGARAY L, CHAE J, CHAO N, CACCONE A. Characterization of microsatellite loci for the Amazonian rummy‐nose tetra, Hemigrammus bleheri (Teleostei, Characidae). Molecular Ecology Resources 2005, 5: 536-537. DOI: 10.1111/j.1471-8286.2005.00985.x.Peer-Reviewed Original ResearchRummy-nose tetraHemigrammus bleheriVariable genetic markersMicrosatellite DNA lociNumber of allelesMiddle Rio NegroDNA lociMicrosatellite lociPopulation historyConservation unitsForest streamsGenetic markersSmall fishCentral AmazoniaFishery resourcesLociRiverine peopleFishRio NegroHeterozygositySpeciesAllelesAmazoniaAquariaImportant tool
1996
Intraspecific nuclear DNA variation in Drosophila.
Moriyama E, Powell J. Intraspecific nuclear DNA variation in Drosophila. Molecular Biology And Evolution 1996, 13: 261-277. PMID: 8583899, DOI: 10.1093/oxfordjournals.molbev.a025563.Peer-Reviewed Original ResearchConceptsD. melanogasterDNA polymorphismsD. simulansD. pseudoobscuraNeutral theorySpecies of DrosophilaNuclear DNA variationMcDonald-Kreitman testNon-coding DNALevel of polymorphismFourfold degenerate sitesCodon usage biasLevel of variationReplacement polymorphismsNucleotide heterozygosityNoncoding DNAHKA testTajima's testReplacement substitutionsDNA variationSilent sitesGenetic codeAutosomal genesPopulation historyUsage bias
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