2020
Identifying and managing infectious disease syndemics in patients with HIV.
Bromberg DJ, Mayer KH, Altice FL. Identifying and managing infectious disease syndemics in patients with HIV. Current Opinion In HIV And AIDS 2020, 15: 232-242. PMID: 32487816, PMCID: PMC7376494, DOI: 10.1097/coh.0000000000000631.Peer-Reviewed Original ResearchConceptsInfectious diseasesDisease progressionHIV disease progressionInfluence of HIVEvidence-based interventionsAntiretroviral therapyHIV acquisitionPsychiatric comorbidityRisky sex behaviorsHIVRisk behaviorsDiseaseSubstance useInfectionSex behaviorDisease synergismSyndemicSynergistic interactionIntervention strategiesBehavioral determinantsPatientsMultipronged approachProgressionStructural determinantsPast year
2018
Antibacterial mechanisms of cinnamon and its constituents: A review
Vasconcelos N, Croda J, Simionatto S. Antibacterial mechanisms of cinnamon and its constituents: A review. Microbial Pathogenesis 2018, 120: 198-203. PMID: 29702210, DOI: 10.1016/j.micpath.2018.04.036.Peer-Reviewed Original ResearchConceptsAntibacterial mechanismGram-negative bacteriaCell divisionMembrane porinsBiofilm formationPotential new sourceCell membraneResistant bacterial infectionsAnti-quorum sensing effectsPathogenic GramCurrent knowledgeBacteriaBacterial infectionsNew antibioticsCommercial antibioticsMulti-drug resistant bacterial infectionsSynergistic interactionTypes of mechanismsAntibacterial actionATPasesPorinCinnamic acidMechanismAntibacterial agentsGlobal health threat
2017
Further characterization of Maize chlorotic mottle virus and its synergistic interaction with Sugarcane mosaic virus in maize
Wang Q, Zhang C, Wang C, Qian Y, Li Z, Hong J, Zhou X. Further characterization of Maize chlorotic mottle virus and its synergistic interaction with Sugarcane mosaic virus in maize. Scientific Reports 2017, 7: 39960. PMID: 28059116, PMCID: PMC5216416, DOI: 10.1038/srep39960.Peer-Reviewed Original ResearchConceptsCorn lethal necrosis diseaseMCMV-infected cellsCo-infected cellsInfectious cloneMCMV infectionSugarcane mosaic virusCytopathological changesMCMVMCMV isolatesVirusInjection procedureNecrosis diseaseEpidemiologyMaize chlorotic mottle virusMosaic virusLethal necrosis diseaseFurther characterizationSynergistic interactionCellsInfectionDiseaseMottle virus
2010
Inference of Population History by Coupling Exploratory and Model-Driven Phylogeographic Analyses
Garrick R, Caccone A, Sunnucks P. Inference of Population History by Coupling Exploratory and Model-Driven Phylogeographic Analyses. International Journal Of Molecular Sciences 2010, 11: 1190-1227. PMID: 20480016, PMCID: PMC2871112, DOI: 10.3390/ijms11041190.Peer-Reviewed Original ResearchConceptsPhylogeographic analysisGene treesGenetic diversityConservation managementPopulation historyDNA sequencesGenetic datasetsGenetic dataCladistic analysisHistorical inferencesPopulation processesTemporal concordanceSynergistic interactionDiversitySpeciationSpatial distributionSequenceGeographic contextTrees
2006
Synergistic association of mitochondrial uncoupling protein (UCP) genes with schizophrenia
Yasuno K, Ando S, Misumi S, Makino S, Kulski JK, Muratake T, Kaneko N, Amagane H, Someya T, Inoko H, Suga H, Kanemoto K, Tamiya. Synergistic association of mitochondrial uncoupling protein (UCP) genes with schizophrenia. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2006, 144B: 250-253. PMID: 17066476, DOI: 10.1002/ajmg.b.30443.Peer-Reviewed Original ResearchMeSH KeywordsAllelesFemaleGenetic Predisposition to DiseaseHumansIon ChannelsLogistic ModelsMaleMembrane Transport ProteinsMitochondrial ProteinsMitochondrial Uncoupling ProteinsModels, GeneticNerve Tissue ProteinsNeuronsPolymorphism, Single NucleotideSchizophreniaSoftwareUncoupling Protein 1Uncoupling Protein 2ConceptsNeuronal UCPsCase-control studyPathophysiology of schizophreniaHomozygous risk allelesLogistic regression analysisNeuroprotective effectsTag SNPsBrain tissueModest associationRisk allelesSchizophreniaOxidative stressMitochondrial uncoupling protein (UCP) geneMitochondrial dysfunctionImportant involvementSynergistic interactionUncoupling Protein GeneGenetic etiologySignificant synergistic interactionMultifactor dimensionality reduction methodRegression analysisMultiple comparisonsUCP2Synergistic associationAssociation
2001
Epistasis and the Mutation Load: A Measurement-Theoretical Approach
Hansen T, Wagner G. Epistasis and the Mutation Load: A Measurement-Theoretical Approach. Genetics 2001, 158: 477-485. PMID: 11333254, PMCID: PMC1461645, DOI: 10.1093/genetics/158.1.477.Peer-Reviewed Original ResearchConceptsMutation-selection equilibriumGene interactionsEpistatic interactionsMutation loadStrength of epistasisMutation-selection balanceGenomic mutation rateHigher-order gene interactionsSynergistic epistasisMean fitnessOptimal genotypeEpistatic effectsTwofold disadvantageEpistasisMutation rateGenetic backgroundSynergistic interactionSystematic relationshipGenesLociInteraction intensityInteractionFitnessInteraction densityGenotypes
1998
Inhibition of arterial thrombosis: synergistic interaction between platelet IIb/IIIa receptor and tissue factor
Benedict C, Chen Z, Pawashe A, Ezekowitz M. Inhibition of arterial thrombosis: synergistic interaction between platelet IIb/IIIa receptor and tissue factor. Journal Of The American College Of Cardiology 1998, 31: 498-499. DOI: 10.1016/s0735-1097(98)80523-8.Peer-Reviewed Original Research
1992
Two amino acid substitutions within the capsid are coordinately required for acquisition of fibrotropism by the lymphotropic strain of minute virus of mice
Ball-Goodrich L, Tattersall P. Two amino acid substitutions within the capsid are coordinately required for acquisition of fibrotropism by the lymphotropic strain of minute virus of mice. Journal Of Virology 1992, 66: 3415-3423. PMID: 1316457, PMCID: PMC241122, DOI: 10.1128/jvi.66.6.3415-3423.1992.Peer-Reviewed Original ResearchConceptsRestrictive infectionDouble mutant virusLymphotropic strainViral life cycleMinute virusInfectionImmunosuppressive strainFibroblast infectionVirusParvovirus minute virusMutant virusA9 fibroblastsCodon 317MiceCodon 321Amino acid substitutionsFibroblastsSame cellsCapsid geneCellsGene expressionAcid substitutionsSynergistic interactionNucleotide changesA9 cells
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply