2024
The Integration of Clinical Trials With the Practice of Medicine
Angus D, Huang A, Lewis R, Abernethy A, Califf R, Landray M, Kass N, Bibbins-Domingo K, Abbasi A, Abebe K, Abernethy A, Adam S, Angus D, Ard J, Berkwits M, Bender Ignacio R, Berry S, Bhatt D, Bibbins-Domingo K, Bonow R, Bonten M, Brangman S, Brownstein J, Buntin M, Butte A, Califf R, Campbell M, Cappola A, Chiang A, Cook D, Cummings S, Curfman G, Esserman L, Fleisher L, Franklin J, Gonzalez R, Grossman C, Haddad T, Herbst R, Hernandez A, Holder D, Horn L, Huang G, Huang A, Kass N, Khera R, Koroshetz W, Krumholz H, Landray M, Lewis R, Lieu T, Malani P, Martin C, McClellan M, McDermott M, Morain S, Murphy S, Nicholls S, Nicholls S, O'Dwyer P, Patel B, Peterson E, Prindiville S, Ross J, Rowan K, Rubenfeld G, Seymour C, Taylor R, Waldstreicher J, Wang T. The Integration of Clinical Trials With the Practice of Medicine. JAMA 2024, 332: 153-162. PMID: 38829654, PMCID: PMC12045079, DOI: 10.1001/jama.2024.4088.Peer-Reviewed Original ResearchConceptsHealth care delivery enterpriseHealth care deliveryCare deliveryIntegrity of clinical trialsRandomized clinical trialsHealth careOptimal health care deliveryHealth care delivery systemCare delivery systemLearning health systemElectronic health recordsPractice of medicineHealth recordsImplementation scienceHealth systemHealth dataOptimal careQuality improvementCareNonfinancial incentivesVulnerable populationsPoor accessStudy designClinical trialsHealthIncreased Stigma, and Physical and Sexual Violence Against Men Who Have Sex with Men and Transgender Women in Sub-Saharan Africa: A Qualitative Evidence Synthesis Analyzing Social and Structural Barriers to HIV Testing and Coping Behaviors
Thapa S, Ogunleye T, Shrestha R, Joshi R, Hannes K. Increased Stigma, and Physical and Sexual Violence Against Men Who Have Sex with Men and Transgender Women in Sub-Saharan Africa: A Qualitative Evidence Synthesis Analyzing Social and Structural Barriers to HIV Testing and Coping Behaviors. Journal Of Homosexuality 2024, 72: 245-271. PMID: 38456684, DOI: 10.1080/00918369.2024.2320237.Peer-Reviewed Original ResearchTransgender womenHIV testing servicesStructural barriersSub-Saharan AfricaSub-SaharanSub-Saharan African countriesSame-sex relationshipsHIV testingTesting servicesFear of discriminationAnalyzing socializationPhysical violenceSex relationshipsHIV testing uptakeLack of trustAfrican countriesQualitative evidence synthesisPoor accessIncreased stigmaRisky behaviorsCriminalsQualitative studyMSMTesting uptakeNon-disclosure
2022
The Health and Health Needs of People under Community Supervision
Hawks L, Horton N, Wang E. The Health and Health Needs of People under Community Supervision. The Annals Of The American Academy Of Political And Social Science 2022, 701: 172-190. DOI: 10.1177/00027162221119661.Peer-Reviewed Original ResearchHigh-quality preventive careCommunity-based primary careCommunity-based healthcare systemEvidence-based addiction treatmentAddiction treatment centersExperience higher ratesDischarge planningPreventive carePrimary careChronic diseasesTreatment centersMental illnessHealth needsPoor healthAddiction medicineAddiction treatmentMental healthPoor accessHealthcare systemHigh rateHealthCorrectional systemCarePervasive barriersTreatment
2021
Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases
Trudler D, Ghatak S, Lipton S. Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases. International Journal Of Molecular Sciences 2021, 22: 8196. PMID: 34360966, PMCID: PMC8347370, DOI: 10.3390/ijms22158196.Peer-Reviewed Original ResearchConceptsAmyotrophic lateral sclerosisNeurodegenerative diseasesParkinson's diseaseAnimal modelsAlzheimer's diseaseEffective disease-modifying therapiesHuntington's diseaseDisease-modifying therapiesSeverity of symptomsHuman samplesHiPSC-derived neural cellsHealthy donorsEffective treatmentLateral sclerosisEconomic burdenHuman-induced pluripotent stem cell (hiPSC) technologyProgressive deteriorationNeural functionDiseaseHiPSC modelsNeural cellsPluripotent stem cell (iPSC) technologyDisease mechanismsPoor accessMillions of people
2020
Confronting Structural Racism in the Prevention and Control of Tuberculosis in the United States
Asabor EN, Vermund SH. Confronting Structural Racism in the Prevention and Control of Tuberculosis in the United States. Clinical Infectious Diseases 2020, 73: e3531-e3535. PMID: 33242078, PMCID: PMC8563219, DOI: 10.1093/cid/ciaa1763.Commentaries, Editorials and LettersConceptsStructural racismPeople of colorLow-income workersUnited StatesRacist policiesDisproportionate incarcerationState governmentsVulnerable communitiesMarginalized populationsCrowded prisonsRecent immigrantsHealth servicesEssential health servicesRacismImmigrantsIncarcerationPoor accessAffordable careKey populationsNational averagePreventive health servicesControl of tuberculosisPeopleGovernmentBIPOCUse of Digital Technology to Provide or Enhance the Delivery of Interventions for Adolescents
Camenga D, Kong G. Use of Digital Technology to Provide or Enhance the Delivery of Interventions for Adolescents. 2020, 335-347. DOI: 10.1093/oxfordhb/9780190218058.013.29.ChaptersMental healthcareMental healthcare utilizationMental health disordersMental health servicesDepression/anxietyMental health conditionsDelivery of interventionsMental health diseaseTechnology-based interventionsHealthcare utilizationTobacco smokingHealth disordersHealth servicesSuch careTherapeutic programHealth conditionsHealth diseasesPoor accessOne-thirdAdolescentsCritical periodLack of availabilityUnique needsDisordersInterventionRationale and study design: A randomized controlled trial of early palliative care in newly diagnosed cancer patients in Addis Ababa, Ethiopia
Reid E, Abathun E, Diribi J, Mamo Y, Hall P, Fallon M, Wondemagegnhu T, Grant L. Rationale and study design: A randomized controlled trial of early palliative care in newly diagnosed cancer patients in Addis Ababa, Ethiopia. Contemporary Clinical Trials Communications 2020, 18: 100564. PMID: 32309673, PMCID: PMC7154993, DOI: 10.1016/j.conctc.2020.100564.Peer-Reviewed Original ResearchStandard oncology carePatient-reported outcomesHealthcare utilizationLow-income countriesOncology careCancer patientsEarly palliative carePalliative care provisionTime of enrollmentCost-consequence analysisAddis AbabaQuality of lifeHealth care policyOncology clinicOncology visitsOutcome scoresPalliative carePC providersHome-based PCStudy designCare provisionPoor accessMillions of peopleCarePocket payments
2016
Population Of US Practicing Psychiatrists Declined, 2003–13, Which May Help Explain Poor Access To Mental Health Care
Bishop TF, Seirup JK, Pincus HA, Ross JS. Population Of US Practicing Psychiatrists Declined, 2003–13, Which May Help Explain Poor Access To Mental Health Care. Health Affairs 2016, 35: 1271-1277. PMID: 27385244, DOI: 10.1377/hlthaff.2015.1643.Peer-Reviewed Original ResearchConceptsPrimary care physiciansMental health careCare physiciansMental illnessSupply of psychiatristsHealth carePoor accessSevere mental illnessHospital referral regionsMental health servicesTeam-based carePrimary careMedian numberReferral regionsNonphysician providersUS populationHealth servicesMental healthStudy periodCarePsychiatristsPatientsNeurologistsIllnessPhysicians
2013
Dendrimer Advances for the Central Nervous System Delivery of Therapeutics
Xu L, Zhang H, Wu Y. Dendrimer Advances for the Central Nervous System Delivery of Therapeutics. ACS Chemical Neuroscience 2013, 5: 2-13. PMID: 24274162, PMCID: PMC3894720, DOI: 10.1021/cn400182z.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsBlood-brain barrierCNS therapeutic agentsDendrimer-mediated deliveryTherapeutic agentsCentral nervous system diseaseTreatment of CNSCentral nervous system deliveryNervous system diseasesMost CNS drugsBrain parenchymaSystem diseasesBrain tumorsCNS drugsNoninvasive treatmentCNS therapeuticsPoor accessDeliveryTreatmentTherapeuticsAgentsSystem deliveryTumorsCNSDiseaseDiagnosisNew Media Use by Patients Who Are Homeless: The Potential of mHealth to Build Connectivity
Post LA, Vaca FE, Doran KM, Luco C, Naftilan M, Dziura J, Brandt C, Bernstein S, Jagminas L, D'Onofrio G. New Media Use by Patients Who Are Homeless: The Potential of mHealth to Build Connectivity. Journal Of Medical Internet Research 2013, 15: e195. PMID: 24001876, PMCID: PMC3786002, DOI: 10.2196/jmir.2724.Peer-Reviewed Original ResearchConceptsED patientsHomeless patientsUnmet health care needsCross-sectional observational studyAlcohol/substance abuseEmergency department visitsAdjusted odds ratioHealth care needsStable housingPotential of mHealthDepartment visitsSmoking cessationPrimary careOdds ratioObservational studyCare needsPatientsExperienced homelessnessSubstance abuseMental healthHealth carePoor accessHealth informationSignificant differencesDescriptive statistics
2012
Poor-quality health services and lack of programme support leads to low uptake of HIV testing in rural Mozambique
Audet CM, Groh K, Moon TD, Vermund SH, Sidat M. Poor-quality health services and lack of programme support leads to low uptake of HIV testing in rural Mozambique. African Journal Of AIDS Research 2012, 11: 327-335. PMID: 25860191, PMCID: PMC4837645, DOI: 10.2989/16085906.2012.754832.Peer-Reviewed Original ResearchPatient's HIV statusHIV statusHIV testingHIV infectionHigh burdenPoor quality health servicesFood supplement programWorld's highest burdenClinical service deliveryHIV diseaseZambézia ProvinceClinical practiceHealth servicesLow uptakePoor accessFatalistic beliefsHIVRural districtsInfectionFocus group discussionsRural MozambiquePurposeful samplingGender-specific focus group discussionsIntentional disclosureService delivery
2011
Barriers to Health Care Access among Refugee Asylum Seekers
Asgary R, Segar N. Barriers to Health Care Access among Refugee Asylum Seekers. Journal Of Health Care For The Poor And Underserved 2011, 22: 506-522. PMID: 21551930, DOI: 10.1353/hpu.2011.0047.Peer-Reviewed Original ResearchConceptsAsylum seekersCultural competencyRefugee asylum seekersInadequate community supportCommunity-based organizationsResettlement challengesEmployment insecuritySocial programsSocial assimilationOrganization representativesCommunity supportQualitative dataAfrican countriesHealth care accessFocus groupsSeekersHealth careLimited servicesComprehensive interviewPoor accessMedical interpretersInterviewsMental health servicesPurposive samplingHealth servicesProject Access-New Haven: improving access to specialty care for patients without insurance.
Spatz ES, Phipps MS, Lagarde S, Borgstrom C, Hunter AE, Wang OJ, Rosenthal MS, Lucas G. Project Access-New Haven: improving access to specialty care for patients without insurance. Connecticut Medicine 2011, 75: 349-54. PMID: 21755852.Peer-Reviewed Original ResearchConceptsSpecialty careSpecialty physiciansSpecialty care needsTimely medical careQuality health careHealth care networkPatient navigationPatient navigatorsEmergency departmentUninsured adultsLocal hospitalMedical careMore physiciansPatientsHospitalCareVulnerable populationsHealth carePhysiciansPoor accessFurther data
2010
Racial Disparities in Health Literacy and Access to Care Among Patients With Heart Failure
Chaudhry SI, Herrin J, Phillips C, Butler J, Mukerjhee S, Murillo J, Onwuanyi A, Seto TB, Spertus J, Krumholz HM. Racial Disparities in Health Literacy and Access to Care Among Patients With Heart Failure. Journal Of Cardiac Failure 2010, 17: 122-127. PMID: 21300301, PMCID: PMC3053061, DOI: 10.1016/j.cardfail.2010.09.016.Peer-Reviewed Original ResearchConceptsHeart failure patientsHealth literacyFailure patientsHeart failureInsurance statusWorse health literacyOutpatient medical careRacial differencesImportant racial differencesNoncardiac comorbiditiesUnadjusted analysesBlack raceCare existMedical homePatientsMedical careRacial disparitiesSocioeconomic statusStrong associationPotential mediatorsHealth carePoor accessCareSocial supportStatus
1993
Differences between men and women with HIV-related Pneumocystis carinii pneumonia: experience from 3,070 cases in New York City in 1987.
Bastian L, Bennett C, Adams J, Waskin H, Divine G, Edlin B. Differences between men and women with HIV-related Pneumocystis carinii pneumonia: experience from 3,070 cases in New York City in 1987. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1993, 6: 617-23. PMID: 8496791.Peer-Reviewed Original ResearchConceptsPneumocystis carinii pneumoniaCarinii pneumoniaEmergency roomPrivate health insuranceMortality rateShort-term mortality rateHuman immunodeficiency virusRisk of deathHospital resource useHealth insuranceLogistic regression modelsLess experienceImmunodeficiency virusHospital characteristicsAge 60HospitalMedical careSociodemographic characteristicsNew York CityHIVWomenPoor accessCareMenPneumonia
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