2023
Racial disparities in surgical outcomes after mastectomy in 223 000 female breast cancer patients: a retrospective cohort study
Knoedler S, Kauke-Navarro M, Knoedler L, Friedrich S, Matar D, Diatta F, Mookerjee V, Ayyala H, Wu M, Kim B, Machens H, Pomahac B, Orgill D, Broer P, Panayi A. Racial disparities in surgical outcomes after mastectomy in 223 000 female breast cancer patients: a retrospective cohort study. International Journal Of Surgery 2023, 110: 684-699. PMID: 38052017, PMCID: PMC10871660, DOI: 10.1097/js9.0000000000000909.Peer-Reviewed Original ResearchAmerican Indian/Alaska Native womenBreast cancer patientsAlaska Native womenSurgical complicationsRadical mastectomyPartial mastectomyCancer patientsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseFemale breast cancer patientsNon-home dischargeRetrospective cohort studyImprovement Program databaseLikelihood of readmissionBreast cancer mortalityBreast cancer surgeryAfrican American patientsAmerican Indians/Alaska NativesBlack/African AmericanNative Hawaiian/Pacific IslanderComplication occurrencePerioperative complicationsPerioperative outcomesAdverse events
2022
Does Breast Cancer Subtype Impact Margin Status in Patients Undergoing Partial Mastectomy?
Horattas I, Fenton A, Gabra J, Mendiola A, Li F, Namm J, Solomon N, Gass J, Lum S, Murray M, Howard-McNatt M, Dupont E, Levine E, Brown E, Ollila D, Chiba A, Chagpar AB. Does Breast Cancer Subtype Impact Margin Status in Patients Undergoing Partial Mastectomy? The American Surgeon 2022, 88: 1607-1612. PMID: 34982015, DOI: 10.1177/00031348211069783.Peer-Reviewed Original ResearchConceptsCavity shave marginsMargin statusPartial mastectomyMolecular subtypesBreast cancer stage IOverall positive margin rateStandard partial mastectomyBreast-Conserving TherapyCancer stage IInvasive breast cancerImpact of subtypePositive margin rateBreast cancer subtypesLymphovascular invasionSurgical therapySystemic therapyRandomized trialsSurgical marginsShave marginsInvasive carcinomaMargin rateBreast cancerHispanic ethnicityStage IPatients
2020
Paget disease of the breast: A national retrospective analysis of the US population
Sisti A, Huayllani MT, Restrepo DJ, Boczar D, Advani P, Lu X, Spaulding AC, Ball CT, McLaughlin SA, Forte AJ. Paget disease of the breast: A national retrospective analysis of the US population. Breast Disease 2020, 39: 119-126. PMID: 32390594, DOI: 10.3233/bd-200439.Peer-Reviewed Original ResearchConceptsNational Cancer DatabasePaget's diseaseComplete mastectomyPartial mastectomyCommon treatmentSurvival rateRegional lymph node metastasisBlack race/ethnicityHigher cancer stageNational retrospective analysisOverall survival rateLymph node metastasisLarger tumor sizeHigh tumor gradeRace/ethnicityMedian ageNode metastasisFemale patientsShorter survivalTumor sizeCancer DatabaseCancer stageTumor gradeTreatment characteristicsMetastatic cancer
2019
Resection of Cavity Shave Margins in Stage 0–III Breast Cancer Patients Undergoing Breast Conserving Surgery
Dupont E, Tsangaris T, Garcia-Cantu C, Howard-McNatt M, Chiba A, Berger AC, Levine EA, Gass JS, Gallagher K, Lum SS, Martinez RD, Willis AI, Pandya SV, Brown EA, Fenton A, Mendiola A, Murray M, Solomon NL, Senthil M, Ollila DW, Edmonson D, Lazar M, Namm JP, Li F, Butler M, McGowan NE, Herrera ME, Avitan YP, Yoder B, Walters LL, McPartland T, Chagpar AB. Resection of Cavity Shave Margins in Stage 0–III Breast Cancer Patients Undergoing Breast Conserving Surgery. Annals Of Surgery 2019, 273: 876-881. PMID: 31290763, DOI: 10.1097/sla.0000000000003449.Peer-Reviewed Original ResearchConceptsCavity shave marginsBreast cancer patientsPartial mastectomyPositive marginsRe-excision ratesCancer patientsShave marginsStage 0Standard partial mastectomyMedian patient ageSingle-center studyBreast conserving surgeryPrimary outcome measurePositive margin rateConserving surgeryPatient ageClinicopathologic factorsMargin clearanceMargin rateInclusion criteriaOutcome measuresPatientsResectionPractice settingsMastectomy
2017
Economic Impact of Routine Cavity Margins Versus Standard Partial Mastectomy in Breast Cancer Patients
Chagpar AB, Horowitz NR, Killelea BK, Tsangaris T, Longley P, Grizzle S, Loftus M, Li F, Butler M, Stavris K, Yao X, Harigopal M, Bossuyt V, Lannin DR, Pusztai L, Davidoff AJ, Gross CP. Economic Impact of Routine Cavity Margins Versus Standard Partial Mastectomy in Breast Cancer Patients. Annals Of Surgery 2017, 265: 39-44. PMID: 27192352, PMCID: PMC5605915, DOI: 10.1097/sla.0000000000001799.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingCarcinoma, LobularConnecticutFemaleFollow-Up StudiesHealth ExpendituresHospital CostsHumansMargins of ExcisionMastectomy, SegmentalMiddle AgedProspective StudiesReoperationSingle-Blind MethodTreatment OutcomeConceptsCavity shave marginsStandard partial mastectomyPartial mastectomyRe-excision ratesIndex surgeryInitial surgeryBreast cancerHospital perspectiveLower re-excision ratesDirect hospital costsBreast cancer patientsOperating room timeReoperative surgeryBaseline characteristicsOperative timePositive marginsShave marginsCancer patientsHospital costsStage 0Room timeSurgeryPathology costsPatientsMastectomy
2015
A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer
Chagpar AB, Killelea BK, Tsangaris TN, Butler M, Stavris K, Li F, Yao X, Bossuyt V, Harigopal M, Lannin DR, Pusztai L, Horowitz NR. A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer. New England Journal Of Medicine 2015, 373: 503-510. PMID: 26028131, PMCID: PMC5584380, DOI: 10.1056/nejmoa1504473.Peer-Reviewed Original ResearchConceptsCavity shave marginsPositive marginsPartial mastectomyShave marginsDuctal carcinomaBreast cancerInvasive cancerOutcome measuresStandard partial mastectomySecondary outcome measuresPrimary outcome measureLower ratesRoutine resectionMedian ageClinicopathological characteristicsCavity shavingMargin clearanceSecond surgeryInvasive carcinomaStage 0MastectomyPathological testingPatientsFurther diseaseVolume of tissueCan routine cavity shave margins (CSM) improve local control in breast cancer? Initial results of the SHAVE trial, a prospective randomized controlled trial of routine CSM vs. standard partial mastectomy (SPM).
Chagpar A, Killelea B, Tsangaris T, Butler M, Stavris K, Yao X, Li F, Bossuyt V, Pusztai L, Horowitz N. Can routine cavity shave margins (CSM) improve local control in breast cancer? Initial results of the SHAVE trial, a prospective randomized controlled trial of routine CSM vs. standard partial mastectomy (SPM). Journal Of Clinical Oncology 2015, 33: 1012-1012. DOI: 10.1200/jco.2015.33.15_suppl.1012.Peer-Reviewed Original Research
2014
Does three-dimensional intraoperative specimen imaging reduce the need for re-excision in breast cancer patients?
Chagpar A, Butler M, Killelea B, Horowitz N, Stavris K, Lannin D. Does three-dimensional intraoperative specimen imaging reduce the need for re-excision in breast cancer patients? Journal Of Clinical Oncology 2014, 32: 107-107. DOI: 10.1200/jco.2014.32.30_suppl.107.Peer-Reviewed Original ResearchMargin statusIntraoperative imagingFinal margin statusMedian tumor sizeBreast cancer patientsRe-excision ratesIntraoperative specimen radiographyCohort of interestIntraoperative marginsResidual tumorPartial mastectomyPositive marginsProspective studyTumor sizeCancer patientsInvasive cancerFurther excisionPathology resultsIntraoperative resectionPatientsDefinitive specimenSpecimen radiographyIntraoperative specimenSurgeons
2013
SHAVE: A randomized controlled trial of routine shave margins versus standard partial mastectomy.
Chagpar A, Stavris K, Killelea B, Tsangaris T, Horowitz N. SHAVE: A randomized controlled trial of routine shave margins versus standard partial mastectomy. Journal Of Clinical Oncology 2013, 31: tps1145-tps1145. DOI: 10.1200/jco.2013.31.15_suppl.tps1145.Peer-Reviewed Original ResearchStandard partial mastectomyPositive margin ratePartial mastectomyRe-excision ratesShave marginsCosmetic outcomeMargin rateBreast cancerVolume of tissueCavity shave marginsNeoadjuvant chemotherapyPrimary endpointMastectomy groupLocal recurrenceOperative timeOutcome measuresStage 0Intraoperative timeMargin groupMost seriesPatientsMastectomyInformed consentAdditional tissueOperating roomThe association of preoperative breast magnetic resonance imaging and multiple breast surgeries among older women with early stage breast cancer
Wang SY, Kuntz KM, Tuttle TM, Jacobs DR, Kane RL, Virnig BA. The association of preoperative breast magnetic resonance imaging and multiple breast surgeries among older women with early stage breast cancer. Breast Cancer Research And Treatment 2013, 138: 137-147. PMID: 23354364, DOI: 10.1007/s10549-013-2420-6.Peer-Reviewed Original ResearchConceptsEarly-stage breast cancerStage breast cancerMultiple surgeriesPreoperative breast MRIBreast cancerAdditional surgeryBreast surgeryPreoperative breast magnetic resonance imagingEnd Results-Medicare databaseBreast MRIInitial treatment episodeMore additional surgeriesPhysician-level predictorsBreast magnetic resonance imagingMagnetic resonance imaging (MRI) utilizationInitial treatment periodMultilevel logistic regression modelsMedian odds ratioMagnetic resonance imagingLogistic regression modelsPrimary surgeryTumor characteristicsMRI evaluationPartial mastectomyTreatment episodes
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply