2025
Racial and ethnic disparities in conversion to mastectomy following lumpectomy
Khubchandani J, KC M, Dey P, Proussaloglou E, Valero M, Berger E, Park T, Gross C, Butler P, Fayanju O, Winer E, Golshan M, Greenup R. Racial and ethnic disparities in conversion to mastectomy following lumpectomy. Breast Cancer Research And Treatment 2025, 211: 99-110. PMID: 39937397, DOI: 10.1007/s10549-025-07625-6.Peer-Reviewed Original ResearchConceptsConversion to mastectomyNeoadjuvant chemotherapyBreast conservationStage 0-III breast cancerWhite womenBreast cancerBlack womenBreast cancer careNational Cancer DatabaseMultivariate logistic regression modelEvaluate contemporary trendsLogistic regression modelsCancer careImprove disparitiesEthnic disparitiesDiagnosis yearInitial lumpectomySocio-DemographicCancer DatabaseClinical factorsMastectomyLumpectomySurgeryResultsThe studyTreatment sequence
2024
ASO Visual Abstract: National Patterns of Hospital Admission Versus Home Recovery Following Mastectomy for Breast Cancer
Kim L, Moore M, Schneider E, Canner J, Ayyala H, Chen J, Anant P, Graetz E, Lynch M, Zanieski G, Gillego A, Valero M, Proussaloglou E, Berger E, Golshan M, Greenup R, Park T. ASO Visual Abstract: National Patterns of Hospital Admission Versus Home Recovery Following Mastectomy for Breast Cancer. Annals Of Surgical Oncology 2024, 31: 9113-9113. DOI: 10.1245/s10434-024-16259-9.Peer-Reviewed Original ResearchNational Patterns of Hospital Admission Versus Home Recovery Following Mastectomy for Breast Cancer
Kim L, Moore M, Schneider E, Canner J, Ayyala H, Chen J, Anant P, Graetz E, Lynch M, Zanieski G, Gillego A, Valero M, Proussaloglou E, Berger E, Golshan M, Greenup R, Park T. National Patterns of Hospital Admission Versus Home Recovery Following Mastectomy for Breast Cancer. Annals Of Surgical Oncology 2024, 31: 9088-9099. PMID: 39322830, DOI: 10.1245/s10434-024-16107-w.Peer-Reviewed Original ResearchHR patientsLymph nodesRate of neoadjuvant chemotherapyHospital admissionNational patterns of careEmergency departmentDecrease wound complicationsNeoadjuvant chemo-Hospital re-admissionNeoadjuvant chemotherapyIn-hospital admissionRate of reconstructionPerioperative outcomesPostoperative hematomaComplication ratePostoperative complicationsWound complicationsHome recoveryPatterns of careBreast cancerMastectomyEmergency room visitsMultivariate analysisComplicationsPatients“Peace of Mind” After Mastectomy: A Scoping Review
Hamid S, Bakkila B, Schultz K, Grimshaw A, Gunderson C, Godfrey E, Lee C, Berger E, Rosenberg S, Greenup R. “Peace of Mind” After Mastectomy: A Scoping Review. Annals Of Surgical Oncology 2024, 31: 5168-5179. PMID: 38717543, DOI: 10.1245/s10434-024-15360-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsContralateral prophylactic mastectomyUnilateral mastectomyBreast-Conserving TherapyAverage-risk womenInclusion criteriaPsychosocial Well-BeingProspective cohort studyBackgroundMany womenProphylactic mastectomyScoping ReviewMethodsNine databasesWhite/Caucasian womenCohort studyStudy samplePostoperative time pointsStatistically significant resultsRelevant articlesWell-beingAnxietyResultsThe inclusion criteriaWomenMastectomySignificant resultsSurgical choiceSurgical decision
2023
The significance of timing in breast reconstruction after mastectomy: An ACS-NSQIP analysis
Knoedler S, Kauke-Navarro M, Knoedler L, Friedrich S, Ayyala H, Haug V, Didzun O, Hundeshagen G, Bigdeli A, Kneser U, Machens H, Pomahac B, Orgill D, Broer P, Panayi A. The significance of timing in breast reconstruction after mastectomy: An ACS-NSQIP analysis. Journal Of Plastic Reconstructive & Aesthetic Surgery 2023, 89: 40-50. PMID: 38134626, DOI: 10.1016/j.bjps.2023.11.049.Peer-Reviewed Original ResearchImmediate BRTime pointsACS-NSQIP databaseLow complication rateACS-NSQIP AnalysisBreast cancer patientsBreast reconstruction optionsAutologous cohortsComplication rateSignificance of timingFemale patientsMedical complicationsMultivariable analysisMore complicationsPatient eligibilityCancer patientsBreast reconstructionOncological purposesPatientsComplicationsReconstruction optionsPropensity scoreCase workupMastectomyEligibilitySLAM-based Surgical Guidance For Breast Reconstruction Surgery
Fu E, Alarcón de la Lastra Á, Zhou H, Zhang R, Broyles J, Ayyala H, Pomahac B, Jayender J. SLAM-based Surgical Guidance For Breast Reconstruction Surgery. 2023, 1-2. DOI: 10.31256/hsmr2023.1.Peer-Reviewed Original Research
2022
ASO Visual Abstract: Comparison of Outcomes Between BRCA Pathogenic Variant Carriers Undergoing Breast-Conserving Surgery and Those Treated With Mastectomy
Shubeck S, Sevilimedu V, Berger E, Robson M, Heerdt A, Pilewskie M. ASO Visual Abstract: Comparison of Outcomes Between BRCA Pathogenic Variant Carriers Undergoing Breast-Conserving Surgery and Those Treated With Mastectomy. Annals Of Surgical Oncology 2022, 29: 4714-4715. DOI: 10.1245/s10434-022-11813-9.Peer-Reviewed Original Research
2021
Milestone Studies in Breast Cancer Surgery
Chagpar A. Milestone Studies in Breast Cancer Surgery. 2021, 9-17. DOI: 10.1007/978-3-030-73147-2_2.Peer-Reviewed Original ResearchBreast cancer surgeryCancer surgerySentinel node biopsyBreast-conserving surgeryPostoperative cosmetic outcomeBreast cancer managementAxillary dissectionNode biopsyRadical mastectomyLandmark trialsSurgical managementSurgical interventionCosmetic outcomeMargin clearanceBreast cancerCancer managementSurgeryRadiation oncologyMultidisciplinary approachOngoing studiesMilestone studyNumber of advancesMastectomyMorbidityAxilla
2020
Management of recurrent bilateral multifocal pseudoangiomatous stromal hyperplasia (PASH)
Xu X, Persing SM, Allam O, Park KE, Mozaffari MA, Lannin DR, Bossuyt V, Alperovich M. Management of recurrent bilateral multifocal pseudoangiomatous stromal hyperplasia (PASH). The Breast Journal 2020, 26: 1814-1817. PMID: 32562297, DOI: 10.1111/tbj.13950.Peer-Reviewed Original ResearchConceptsPseudoangiomatous stromal hyperplasiaStromal hyperplasiaBilateral mastectomyReduction mammoplastyTwo-stage implant-based breast reconstructionImplant-based breast reconstructionExcellent aesthetic outcomesPain reliefBreast enlargementStandard treatmentBreast reconstructionFocal excisionReconstructive surgeryRare caseConservative optionsAesthetic outcomeHyperplastic conditionsMastectomyHyperplasiaMammoplastyMacromastiaPatientsSurgeryExcisionBreast
2019
Resection of Cavity Shave Margins in Stage 0–III Breast Cancer Patients Undergoing Breast Conserving Surgery
Dupont E, Tsangaris T, Garcia-Cantu C, Howard-McNatt M, Chiba A, Berger AC, Levine EA, Gass JS, Gallagher K, Lum SS, Martinez RD, Willis AI, Pandya SV, Brown EA, Fenton A, Mendiola A, Murray M, Solomon NL, Senthil M, Ollila DW, Edmonson D, Lazar M, Namm JP, Li F, Butler M, McGowan NE, Herrera ME, Avitan YP, Yoder B, Walters LL, McPartland T, Chagpar AB. Resection of Cavity Shave Margins in Stage 0–III Breast Cancer Patients Undergoing Breast Conserving Surgery. Annals Of Surgery 2019, 273: 876-881. PMID: 31290763, DOI: 10.1097/sla.0000000000003449.Peer-Reviewed Original ResearchConceptsCavity shave marginsBreast cancer patientsPartial mastectomyPositive marginsRe-excision ratesCancer patientsShave marginsStage 0Standard partial mastectomyMedian patient ageSingle-center studyBreast conserving surgeryPrimary outcome measurePositive margin rateConserving surgeryPatient ageClinicopathologic factorsMargin clearanceMargin rateInclusion criteriaOutcome measuresPatientsResectionPractice settingsMastectomy
2018
Impact of incidental findings in preoperative CTA imaging for autologous breast reconstruction
Gabrick KS, Godier-Furnemont A, Chouairi F, Avraham T, Alperovich M. Impact of incidental findings in preoperative CTA imaging for autologous breast reconstruction. Journal Of Plastic Reconstructive & Aesthetic Surgery 2018, 72: 789-794. PMID: 30501967, DOI: 10.1016/j.bjps.2018.11.015.Peer-Reviewed Original ResearchConceptsAutologous breast reconstructionCTA findingsCT angiographyIncidental findingBreast reconstructionPatient careYale-New Haven HospitalPreoperative CT angiographyNew Haven HospitalMetastatic diseaseMedical managementFurther imagingAdditional imagingGynecologic proceduresReconstructive microsurgeonsPatientsImaging reportsPerforator mappingCareBiopsyImagingFindingsReportMastectomyAngiographyAssociations of preoperative breast magnetic resonance imaging with subsequent mastectomy and breast cancer mortality
Wang SY, Long JB, Killelea BK, Evans SB, Roberts KB, Silber AL, Davidoff AJ, Sedghi T, Gross CP. Associations of preoperative breast magnetic resonance imaging with subsequent mastectomy and breast cancer mortality. Breast Cancer Research And Treatment 2018, 172: 453-461. PMID: 30099634, PMCID: PMC6193824, DOI: 10.1007/s10549-018-4919-3.Peer-Reviewed Original ResearchConceptsBreast-conserving surgeryBreast cancer mortalitySubsequent mastectomyCancer mortalityPre-operative MRIBreast cancerSubgroup analysisStage I/II breast cancerEnd Results-Medicare datasetPreoperative breast magnetic resonanceEarly-stage breast cancerMagnetic resonance imaging useReceipt of radiotherapyBreast magnetic resonanceClinical outcomesCox regressionResultsOur sampleImproved outcomesAdjusted ratesMRI useOlder womenLower riskMastectomyImaging useRadiotherapyBilateral mastectomies: can a co-surgeon technique offer improvements over the single-surgeon method?
Mallory MA, Tarabanis C, Schneider E, Nimbkar S, Golshan M. Bilateral mastectomies: can a co-surgeon technique offer improvements over the single-surgeon method? Breast Cancer Research And Treatment 2018, 170: 641-646. PMID: 29687179, PMCID: PMC6026038, DOI: 10.1007/s10549-018-4794-y.Peer-Reviewed Original ResearchConceptsSingle surgeon's techniqueTotal breast weightAxillary procedureComplication rateOperative timeBreast weightChi-square testSS cohortTBW patientsMultivariate linear regression modelPatient ageUnilateral mastectomyBRCA statusBM casesAverage durationComplicationsDemographic characteristicsMastectomyPatientsT-testLinear regression modelsCohortRegression modelsBM proceduresBMAssociations Between Sentinel Lymph Node Biopsy and Complications for Patients with Ductal Carcinoma In Situ
Killelea BK, Long JB, Dang W, Mougalian SS, Evans SB, Gross CP, Wang SY. Associations Between Sentinel Lymph Node Biopsy and Complications for Patients with Ductal Carcinoma In Situ. Annals Of Surgical Oncology 2018, 25: 1521-1529. PMID: 29516364, PMCID: PMC5928184, DOI: 10.1245/s10434-018-6410-0.Peer-Reviewed Original ResearchConceptsSentinel lymph node biopsyBreast-conserving surgeryLymph node biopsySLNB useNode biopsyWound infectionDuctal carcinomaUse of SLNBEnd Results-Medicare datasetIncidence of complicationsShort-term complicationsMonths of diagnosisOlder patientsSubsequent mastectomyInitial treatmentResultsOur sampleConsensus guidelinesHigh riskOlder womenComplicationsMultivariate analysisPatientsWomenDCISMastectomySurgical Management of the Breast
Chagpar A. Surgical Management of the Breast. DeckerMed Complex General Surgical Oncology 2018 DOI: 10.2310/7800.16006.Peer-Reviewed Original ResearchSentinel node biopsySurgical managementAxillary dissectionNode biopsyBreast cancerBreast surgical oncologyKey clinical trialsNode-positive diseaseBreast-conserving surgeryCompletion dissectionBreast conservationRadical mastectomyClinical trialsSurgical oncologyRadiation therapyLeading malignancyCancerDissectionMastectomyBiopsyMalignancyKey wordsChemotherapyManagementSurgerySurgical Management of the Breast
Chagpar A. Surgical Management of the Breast. DeckerMed CGSO Case-Based Reviews 2018 DOI: 10.2310/cgso.16006.Peer-Reviewed Original ResearchSentinel node biopsySurgical managementAxillary dissectionNode biopsyBreast cancerBreast surgical oncologyKey clinical trialsNode-positive diseaseBreast-conserving surgeryCompletion dissectionBreast conservationRadical mastectomyClinical trialsSurgical oncologyRadiation therapyLeading malignancyCancerDissectionMastectomyBiopsyMalignancyKey wordsChemotherapyManagementSurgery
2017
Breast Cancer after Augmentation
Cho E, Shammas R, Phillips B, Greenup R, Hwang E, Hollenbeck S. Breast Cancer after Augmentation. Plastic & Reconstructive Surgery 2017, 139: 1240e-1249e. PMID: 28538550, DOI: 10.1097/prs.0000000000003342.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBreast ImplantationBreast ImplantsBreast NeoplasmsCohort StudiesFemaleFollow-Up StudiesHumansIncidenceLogistic ModelsMammaplastyMastectomyMiddle AgedMultivariate AnalysisPostoperative ComplicationsReference ValuesRetrospective StudiesRisk AssessmentStatistics, NonparametricSurgical FlapsTime FactorsTreatment OutcomeUnited StatesConceptsPrior augmentationBreast cancer stageBreast cancerSubglandular augmentationCancer stageImplant placementCLINICAL QUESTION/LEVELPreferred reconstructive methodAdvanced breast tumorsTwo-stage implant reconstructionInvasive breast cancerBreast cancer screeningBreast cancer diagnosisUndergoing mastectomySubpectoral implantsDuctal carcinomaTherapeutic mastectomyCancer screeningTreatment recommendationsImplant reconstructionSubpectoral augmentationAuthors' institutionBreast augmentationMastectomyBreast tumorsThe Relationship Between Geographic Access to Plastic Surgeons and Breast Reconstruction Rates Among Women Undergoing Mastectomy for Cancer
Bauder AR, Gross CP, Killelea BK, Butler PD, Kovach SJ, Fox JP. The Relationship Between Geographic Access to Plastic Surgeons and Breast Reconstruction Rates Among Women Undergoing Mastectomy for Cancer. Annals Of Plastic Surgery 2017, 78: 324-329. PMID: 28177978, DOI: 10.1097/sap.0000000000000849.Peer-Reviewed Original ResearchConceptsBreast reconstruction ratesPlastic surgeon densityBreast reconstructionSurgeon densityGeographic accessPlastic surgeonsHealth service area (HSA) levelAmbulatory surgery dataAppropriate clinical expertiseNational health care policyReconstruction rateHealth care policyFinal cohortInsurance statusPostmastectomy reconstructionBreast cancerClinical expertiseSurgery dataAdult womenMastectomyDensity areasRacial disparitiesSurgeonsCare policyWomenDoes Smoking History Confer a Higher Risk for Reconstructive Complications in Nipple‐Sparing Mastectomy?
Frey JD, Alperovich M, Levine JP, Choi M, Karp NS. Does Smoking History Confer a Higher Risk for Reconstructive Complications in Nipple‐Sparing Mastectomy? The Breast Journal 2017, 23: 415-420. PMID: 28097778, DOI: 10.1111/tbj.12760.Peer-Reviewed Original ResearchConceptsPack-year smoking historyNipple-sparing mastectomyComplete NAC necrosisHistory of smokingSmoking historyReconstructive complicationsNAC necrosisHigh riskNipple-areola complex necrosisNew York University Langone Medical CenterPack-year historyMastectomy flap necrosisActive smokersFlap necrosisRisk factorsMedical CenterReconstructive outcomesComplicationsMastectomyNecrosisNonsmokersOutcomesSmokersSmokingPatientsEconomic Impact of Routine Cavity Margins Versus Standard Partial Mastectomy in Breast Cancer Patients
Chagpar AB, Horowitz NR, Killelea BK, Tsangaris T, Longley P, Grizzle S, Loftus M, Li F, Butler M, Stavris K, Yao X, Harigopal M, Bossuyt V, Lannin DR, Pusztai L, Davidoff AJ, Gross CP. Economic Impact of Routine Cavity Margins Versus Standard Partial Mastectomy in Breast Cancer Patients. Annals Of Surgery 2017, 265: 39-44. PMID: 27192352, PMCID: PMC5605915, DOI: 10.1097/sla.0000000000001799.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingCarcinoma, LobularConnecticutFemaleFollow-Up StudiesHealth ExpendituresHospital CostsHumansMargins of ExcisionMastectomy, SegmentalMiddle AgedProspective StudiesReoperationSingle-Blind MethodTreatment OutcomeConceptsCavity shave marginsStandard partial mastectomyPartial mastectomyRe-excision ratesIndex surgeryInitial surgeryBreast cancerHospital perspectiveLower re-excision ratesDirect hospital costsBreast cancer patientsOperating room timeReoperative surgeryBaseline characteristicsOperative timePositive marginsShave marginsCancer patientsHospital costsStage 0Room timeSurgeryPathology costsPatientsMastectomy
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