2024
Healthcare Resource Use Associated With Tumor-Induced Osteomalacia: A Literature Review
de Beur S, Dahir K, Imel E, Zanchetta M, Williams A, Li Z, Webb N, Crowe V, Johnson B, Carpenter T. Healthcare Resource Use Associated With Tumor-Induced Osteomalacia: A Literature Review. The Journal Of Clinical Endocrinology & Metabolism 2024, 110: 102-113. PMID: 38913723, PMCID: PMC11651676, DOI: 10.1210/clinem/dgae431.Peer-Reviewed Original ResearchTumor-induced osteomalaciaHealthcare resource useResection outcomesCase reportHigher probability of tumor recurrenceSecrete fibroblast growth factor 23Probability of tumor recurrenceAssociated with tumor-induced osteomalaciaFibroblast growth factor 23Symptoms to diagnosisHealthcare resource burdenTumor recurrenceParaneoplastic syndromeTumor resectionAssociated with greater usePharmacological treatmentDisease characteristicsImaging testsPatientsMusculoskeletal symptomsTargeted literature reviewResource useOrthopedic surgeryProgressive disabilityMean time
2022
Microangiopathic Hemolytic Anemia Is a Late and Fatal Complication of Gastric Signet Ring Cell Carcinoma: A Systematic Review and Case-Control Study
Lam R, Tarangelo N, Wang R, Horibe M, Grimshaw AA, Jain D, Haffar S, Bazerbachi F, Kunz PL, Li DK. Microangiopathic Hemolytic Anemia Is a Late and Fatal Complication of Gastric Signet Ring Cell Carcinoma: A Systematic Review and Case-Control Study. The Oncologist 2022, 27: 751-759. PMID: 35589098, PMCID: PMC9438916, DOI: 10.1093/oncolo/oyac093.Peer-Reviewed Original ResearchConceptsGastric signet ring cell carcinomaSignet ring cell carcinomaMicroangiopathic hemolytic anemiaHemolytic anemiaCell carcinomaMultivariable Cox proportional hazards regression modelingCox proportional hazards regression modelingSystematic reviewRare paraneoplastic syndromeStage-matched casesEnd Results (SEER) databaseLate-stage complicationsRisk of mortalityCase-control studyBone painParaneoplastic syndromeFatal complicationMedian survivalMetastatic diseaseOverall survivalLymph nodesIndex presentationPrognostic featuresResults databasePooled cohortMononeuritis multiplex as a rare and severe neurological complication of immune checkpoint inhibitors: a case report
Abdelhakim S, Klapholz JD, Roy B, Weiss SA, McGuone D, Corbin ZA. Mononeuritis multiplex as a rare and severe neurological complication of immune checkpoint inhibitors: a case report. Journal Of Medical Case Reports 2022, 16: 81. PMID: 35197122, PMCID: PMC8867751, DOI: 10.1186/s13256-022-03290-1.Peer-Reviewed Original ResearchConceptsImmune checkpoint inhibitorsMononeuritis multiplexCheckpoint inhibitorsCell death protein 1/Cytotoxic T-lymphocyte antigen-4Death ligand 1 (PD-L1) axisDeath protein 1/Immune checkpoint inhibitor therapyT-lymphocyte antigen-4Progressive leg weaknessCheckpoint inhibitor therapyProgressive neurologic dysfunctionSevere neurological complicationsAutoimmune peripheral neuropathyNon-Hispanic white femalesSevere side effectsLigand-1 axisChronic steroidsCombination ipilimumabConclusionsIncreased awarenessIntravenous immunoglobulinNeurological complicationsParaneoplastic syndromeAggressive treatmentInhibitor therapy
2020
Opsoclonus-ataxia syndrome and mature ovarian teratoma in an adolescent
Webster EM, Tymon-Rosario J, D'Addario J, Zeybek B, Ratner ES. Opsoclonus-ataxia syndrome and mature ovarian teratoma in an adolescent. Gynecologic Oncology Reports 2020, 33: 100601. PMID: 32637527, PMCID: PMC7327890, DOI: 10.1016/j.gore.2020.100601.Peer-Reviewed Original Research18 F-fluorodeoxyglucose positron emission tomography/computed tomography in the diagnosis of suspected paraneoplastic syndromes: A retrospective analysis
Bresler R, Schroeder H, Chow D, Lim R. 18 F-fluorodeoxyglucose positron emission tomography/computed tomography in the diagnosis of suspected paraneoplastic syndromes: A retrospective analysis. World Journal Of Nuclear Medicine 2020, 19: 124-130. PMID: 32939199, PMCID: PMC7478297, DOI: 10.4103/wjnm.wjnm_48_19.Peer-Reviewed Original ResearchF-FDG PET/CTSuspected paraneoplastic syndromeNegative predictive valueParaneoplastic syndromeF-FDGF-fluorodeoxyglucose positron emission tomography/computed tomographyWhole-body <sup>18</sup>F-FDG PET/CTClinical presentation of tumorsPositron Emission Tomography/Computed TomographySingle-center retrospective studyPredictive valueEmission Tomography/Computed TomographyPresentation of tumorsFollow-up timeElectronic chart reviewPositive predictive valueFollow-up periodSigns and symptomsAncillary diagnostic proceduresDiagnostic imaging toolTomography/Computed TomographyF-fluorodeoxyglucoseClinical presentationDiagnostic challengeRetrospective study
2017
Paraneoplastic Syndromes and Thymic Malignancies: An Examination of the International Thymic Malignancy Interest Group Retrospective Database
Padda SK, Yao X, Antonicelli A, Riess JW, Shang Y, Shrager JB, Korst R, Detterbeck F, Huang J, Burt BM, Wakelee HA, Badve SS. Paraneoplastic Syndromes and Thymic Malignancies: An Examination of the International Thymic Malignancy Interest Group Retrospective Database. Journal Of Thoracic Oncology 2017, 13: 436-446. PMID: 29191778, PMCID: PMC5983900, DOI: 10.1016/j.jtho.2017.11.118.Peer-Reviewed Original ResearchConceptsThymic epithelial tumorsIndependent prognostic factorOverall survivalPrognostic factorsPrognostic roleRetrospective databaseCox proportional hazards modelKaplan-Meier methodRecurrence-free survivalProportional hazards modelParaneoplastic syndromeCumulative incidenceResection statusTotal thymectomyMyasthenia gravisThymic malignanciesHistologic typeSyndrome statusFemale sexTreatment characteristicsEpithelial tumorsHazards modelLower CIRSyndromeMultivariate analysisComparison of surgical approach and extent of resection for Masaoka-Koga Stage I and II thymic tumours in Europe, North America and Asia: an International Thymic Malignancy Interest Group retrospective database analysis†
Fang W, Yao X, Antonicelli A, Gu Z, Detterbeck F, Vallières E, Aye RW, Farivar AS, Huang J, Shang Y, Louie BE. Comparison of surgical approach and extent of resection for Masaoka-Koga Stage I and II thymic tumours in Europe, North America and Asia: an International Thymic Malignancy Interest Group retrospective database analysis†. European Journal Of Cardio-Thoracic Surgery 2017, 52: 26-32. PMID: 28329118, PMCID: PMC6279116, DOI: 10.1093/ejcts/ezx042.Peer-Reviewed Original ResearchConceptsExtent of resectionThymic tumorsStage IAsian patientsSurgical approachOnly independent predictive factorMasaoka-Koga stage IMore stage IOutcomes of patientsPathological stage IIndependent predictive factorsIndependent risk factorOverall survival rateCumulative recurrence rateSmaller tumor sizeRetrospective database analysisNorth American patientsPartial thymectomyAdjuvant therapyParaneoplastic syndromeThymic carcinomaOverall survivalPerformance statusComplete resectionMyasthenia gravis
2016
Postoperative Radiation Therapy Is Associated with Longer Overall Survival in Completely Resected Stage II and III Thymoma—An Analysis of the International Thymic Malignancies Interest Group Retrospective Database
Rimner A, Yao X, Huang J, Antonicelli A, Ahmad U, Korst RJ, Detterbeck F, Gomez DR. Postoperative Radiation Therapy Is Associated with Longer Overall Survival in Completely Resected Stage II and III Thymoma—An Analysis of the International Thymic Malignancies Interest Group Retrospective Database. Journal Of Thoracic Oncology 2016, 11: 1785-1792. PMID: 27346413, PMCID: PMC5257334, DOI: 10.1016/j.jtho.2016.06.011.Peer-Reviewed Original ResearchConceptsPostoperative radiation therapyStage IIOS benefitRadiation therapyUse of PORTMasaoka-Koga stage IIInternational Thymic Malignancy Interest GroupStage II thymomaOverall survival benefitPrimary end pointMultivariate Cox modelLonger overall survivalLog-rank testIndividual patient dataImproved OSParaneoplastic syndromeOverall survivalSurvival benefitOS ratesHistologic subtypePatient populationRetrospective databaseUnivariate analysisCox modelThymoma
2015
Concomitant opsoclonus ataxia and limbic encephalitis as a result of dual anti‐Ri and anti‐Yo antibodies in uterine carcinosarcoma: A case report
Kim J, Pinto A, Nucci M, Lyons J. Concomitant opsoclonus ataxia and limbic encephalitis as a result of dual anti‐Ri and anti‐Yo antibodies in uterine carcinosarcoma: A case report. Clinical And Experimental Neuroimmunology 2015, 7: 75-78. DOI: 10.1111/cen3.12249.Peer-Reviewed Original ResearchAnti-Yo antibodiesLimbic encephalitisParaneoplastic syndromeUterine carcinosarcomaParaneoplastic antibodiesPresence of malignancyAnti-RiConcomitant syndromeOpsoclonus-MyoclonusNeurological symptomsCase reportDegeneration syndromeCase presentationSyndromeTumor sourceEncephalitisMultiple antibodiesCarcinosarcomaAntibodiesAtaxiaMyoclonusMalignancySymptomsCasesHypersensitivity Reaction as a Harbinger of Acute Myeloid Leukemia: A Case Report and Review of the Literature
Cohen JM, Cheng CE, DeSouza A, Nandi TR, Buzney EA, Larson A, Lee WY, Mostaghimi A. Hypersensitivity Reaction as a Harbinger of Acute Myeloid Leukemia: A Case Report and Review of the Literature. Annals Of Dermatology 2015, 27: 190-193. PMID: 25834359, PMCID: PMC4377409, DOI: 10.5021/ad.2015.27.2.190.Peer-Reviewed Original ResearchAcute myeloid leukemiaCutaneous paraneoplastic syndromesParaneoplastic syndromeMyeloid leukemiaSymptoms of malignancyPresence of malignancySix-month historyComplete blood count testBlood count testReview of systemsRecalcitrant dermatosesUnderlying malignancyInitial presentationClinical presentationInitial diagnosisCutaneous reactionsHypersensitivity reactionsCase reportPhysical examMetastatic spreadMalignancySyndromePatientsDermatosesErythroderma
2013
Clinical and Organizational Factors in the Initial Evaluation of Patients With Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Ost DE, Yeung SC, Tanoue LT, Gould MK. Clinical and Organizational Factors in the Initial Evaluation of Patients With Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST Journal 2013, 143: e121s-e141s. PMID: 23649435, PMCID: PMC4694609, DOI: 10.1378/chest.12-2352.Peer-Reviewed Original ResearchConceptsPulmonary function testsParaneoplastic syndromeLung cancerInitial evaluationDistant metastasisFunction testsPhysical examinationThorough historyAmerican CollegeChest Physicians Evidence-Based Clinical Practice GuidelinesEvidence-based clinical practice guidelinesMultidisciplinary teamCancer treatmentCT imagingDefinitive cancer treatmentClinical practice guidelinesTimeliness of careCurrent medical literatureBasic laboratory testsLung cancer diagnosisGuidelines Oversight CommitteeHealth care qualityEvidence-based approachMultimodality therapyChest Physicians
2012
Parathyroid Hormone-Related Protein: An Update
Wysolmerski JJ. Parathyroid Hormone-Related Protein: An Update. The Journal Of Clinical Endocrinology & Metabolism 2012, 97: 2947-2956. PMID: 22745236, PMCID: PMC3431578, DOI: 10.1210/jc.2012-2142.BooksConceptsType 1 PTH/PTHrP receptorPTH/PTHrP receptorCauses of hypercalcemiaCommon paraneoplastic syndromeParaneoplastic syndromeHumoral hypercalcemiaParathyroid hormonePTHrP receptorBreast cancerNormal physiological functionPTHrPDisease statesTranslational researchHypercalcemiaOsteoporosisBedsidePhysiological functionsRelated genesHyperparathyroidismBasic biologyDiabetesMalignancyOsteoarthritisSyndromePTH
2011
Paraneoplastic Syndrome of Inappropriate Antidiuretic Hormone Mimicking Limbic Encephalitis
Blondin NA, Vortmeyer AO, Harel NY. Paraneoplastic Syndrome of Inappropriate Antidiuretic Hormone Mimicking Limbic Encephalitis. JAMA Neurology 2011, 68: 1591-1594. PMID: 22159058, DOI: 10.1001/archneurol.2011.876.Peer-Reviewed Original ResearchConceptsLimbic encephalitisAntidiuretic hormoneParaneoplastic syndromeEctopic secretionMemory impairmentCerebrospinal fluid analysis findingsClassic limbic encephalitisParaneoplastic limbic encephalitisInappropriate antidiuretic hormoneProgressive memory impairmentAcademic medical centerMagnetic resonance imagingPositron emission tomographyOccult malignancyChronic hyponatremiaThorough workupClinical featuresNeuroendocrine tumorsDifferential diagnosisMedical CenterImmunohistochemical analysisEncephalitisResonance imagingEmission tomographyHyponatremia
1998
Amphiphysin and Breast Cancer
DeCamilli P. Amphiphysin and Breast Cancer. 1998 DOI: 10.21236/ada363483.Peer-Reviewed Original ResearchStiff-man syndromeBreast cancerNeuronal proteinsAutoimmune paraneoplastic syndromeBreast cancer patientsHuman breast cancer cell linesBreast cancer cell linesCentral nervous systemRole of amphiphysinCancer cell linesParaneoplastic syndromeCancer patientsNew patientsEarly diagnosisProgressive rigidityRare diseaseNervous systemNeurological diseasesAutoimmunityPatientsDiagnostic proceduresCancerSyndromeCancer cellsKinase Cdk5Stiff-man syndrome in a woman with breast cancer
Rosin L, DeCamilli P, Butler M, Solimena M, Schmitt H, Morgenthaler N, Meinck H. Stiff-man syndrome in a woman with breast cancer. Neurology 1998, 50: 94-98. PMID: 9443464, DOI: 10.1212/wnl.50.1.94.Peer-Reviewed Original Research
1989
Native and a synthetic analogue of the malignancy-associated parathyroid hormone-like protein have in vitro transforming growth factor-like properties.
Insogna KL, Stewart AF, Morris CA, Hough LM, Milstone LM, Centrella M. Native and a synthetic analogue of the malignancy-associated parathyroid hormone-like protein have in vitro transforming growth factor-like properties. Journal Of Clinical Investigation 1989, 83: 1057-1060. PMID: 2537846, PMCID: PMC303783, DOI: 10.1172/jci113947.Peer-Reviewed Original ResearchConceptsGrowth factor-like propertiesParathyroid hormone-like proteinHormone-like proteinNRK-49F cellsParaneoplastic syndromeHumoral hypercalcemiaLatter hormoneHuman tumorsPhysiological actionsPTHHuman dermal fibroblastsSignificant increaseSoft agarDisplay actionsDermal fibroblastsSynthetic peptidesSynthetic analoguesHypercalcemiaMalignancySyndromeTumorsUnique primary structure
1988
Identification of a cDNA encoding a parathyroid hormone-like peptide from a human tumor associated with humoral hypercalcemia of malignancy.
Mangin M, Webb A, Dreyer B, Posillico J, Ikeda K, Weir E, Stewart A, Bander N, Milstone L, Barton D. Identification of a cDNA encoding a parathyroid hormone-like peptide from a human tumor associated with humoral hypercalcemia of malignancy. Proceedings Of The National Academy Of Sciences Of The United States Of America 1988, 85: 597-601. PMID: 2829195, PMCID: PMC279598, DOI: 10.1073/pnas.85.2.597.Peer-Reviewed Original ResearchConceptsParathyroid hormone-like peptideHumoral hypercalcemiaHormone-like peptideCommon paraneoplastic syndromeTumor-derived peptidesHuman renal carcinomaParaneoplastic syndromeNormal human keratinocytesHuman PTHRenal carcinomaHuman tumorsSyndromeHuman keratinocytesHypercalcemiaMalignancyBlot analysisTumorsRNA blot hybridization analysisPartial N-terminal amino acid sequencePeptidesMRNABlot hybridization analysisMature peptideCarcinomaPTH
1987
Identification of a novel 17,000-dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumor associated with humoral hypercalcemia of malignancy.
Burtis WJ, Wu T, Bunch C, Wysolmerski JJ, Insogna KL, Weir EC, Broadus AE, Stewart AF. Identification of a novel 17,000-dalton parathyroid hormone-like adenylate cyclase-stimulating protein from a tumor associated with humoral hypercalcemia of malignancy. Journal Of Biological Chemistry 1987, 262: 7151-7156. PMID: 3584110, DOI: 10.1016/s0021-9258(18)48217-8.Peer-Reviewed Original Research
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply