1995
Enhanced adrenomedullary response and increased susceptibility to neuroglycopenia: Mechanisms underlying the adverse effects of sugar ingestion in healthy children
Jones TW, Borg WP, Boulware SD, McCarthy G, Sherwin RS, Tamborlane WV. Enhanced adrenomedullary response and increased susceptibility to neuroglycopenia: Mechanisms underlying the adverse effects of sugar ingestion in healthy children. The Journal Of Pediatrics 1995, 126: 171-177. PMID: 7844661, DOI: 10.1016/s0022-3476(95)70541-4.Peer-Reviewed Original ResearchConceptsClinical Research CenterHealthy childrenPlasma glucose concentrationAdrenomedullary responseHypoglycemic clampSymptom scoresSugar ingestionStandard oral glucose loadOral glucose loadPlasma epinephrine levelsPlasma glucose levelsGlucose concentrationCognitive effectsSugar-free drinksP300 potentialEpinephrine levelsP300 auditoryGlucose loadInsulin levelsSymptomatic responsePlasma glucoseOral administrationGlucose levelsHormone concentrationsPhysiologic mechanisms
1990
Mild Hypoglycemia and Impairment of Brain Stem and Cortical Evoked Potentials in Healthy Subjects
Jones T, McCarthy G, Tamborlane W, Caprio S, Roessler E, Kraemer D, Starick-Zych K, Allison T, Boulware S, Sherwin R. Mild Hypoglycemia and Impairment of Brain Stem and Cortical Evoked Potentials in Healthy Subjects. Diabetes 1990, 39: 1550-1555. PMID: 2245879, DOI: 10.2337/diab.39.12.1550.Peer-Reviewed Original ResearchConceptsBrain stemPlasma glucoseMild hypoglycemiaCounterregulatory hormonesClamp studiesCortical responsesBaseline levelsBrain stem auditoryEuglycemic clamp studiesEuglycemic insulin clampHypoglycemic clamp studiesBrain stem potentialsCortical Evoked PotentialsP300 potentialGlucose stepInsulin clampHypoglycemia studyCNS functionHealthy subjectsGlucose levelsNeurophysiological changesReported symptomsControl studyHealthy adultsHypoglycemia
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