2022
Simulated Cost-effectiveness and Long-term Clinical Outcomes of Addiction Care and Antibiotic Therapy Strategies for Patients With Injection Drug Use–Associated Infective Endocarditis
Adams JW, Savinkina A, Hudspeth JC, Gai MJ, Jawa R, Marks LR, Linas BP, Hill A, Flood J, Kimmel S, Barocas JA. Simulated Cost-effectiveness and Long-term Clinical Outcomes of Addiction Care and Antibiotic Therapy Strategies for Patients With Injection Drug Use–Associated Infective Endocarditis. JAMA Network Open 2022, 5: e220541. PMID: 35226078, PMCID: PMC8886538, DOI: 10.1001/jamanetworkopen.2022.0541.Peer-Reviewed Original ResearchConceptsOutpatient parenteral antimicrobial therapyIncremental cost-effectiveness ratioOral antibiotic therapyInjection drug use-associated infective endocarditisUsual care strategyAntibiotic therapyOpioid drug useAntibiotic treatment strategiesAntibiotic strategiesCare servicesTreatment strategiesCare strategiesTreatment discontinuationClinical outcomesInfective endocarditisDrug Use-Associated Infective EndocarditisDrug useInpatient intravenous antibiotic therapyLong-term clinical outcomesHigher treatment completion rateIntravenous antibiotic therapyObservational cohort studyPercentage of patientsPostacute care facilityParenteral antimicrobial therapy
2021
Clinical Epidemiology and Outcomes of Pediatric Musculoskeletal Infections
Yi J, Wood JB, Creech CB, Williams D, Jimenez-Truque N, Yildirim I, Sederdahl B, Daugherty M, Hussaini L, Munye M, Tomashek KM, Focht C, Watson N, Anderson EJ, Thomsen I. Clinical Epidemiology and Outcomes of Pediatric Musculoskeletal Infections. The Journal Of Pediatrics 2021, 234: 236-244.e2. PMID: 33771580, PMCID: PMC8238832, DOI: 10.1016/j.jpeds.2021.03.028.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdministration, OralAdolescentAnti-Bacterial AgentsArthritis, InfectiousChildChild, PreschoolCombined Modality TherapyFemaleGram-Negative Bacterial InfectionsGram-Positive Bacterial InfectionsHumansInfantLogistic ModelsMaleMethicillin-Resistant Staphylococcus aureusOrthopedic ProceduresOsteomyelitisRetrospective StudiesStaphylococcal InfectionsTreatment OutcomeUnited StatesConceptsOsteomyelitis/septic arthritisAcute hematogenous osteomyelitisMethicillin-resistant S aureusSeptic arthritisHematogenous osteomyelitisTreatment failureS aureusOral therapyAntibiotic therapyMusculoskeletal infectionsHigher oddsPediatric musculoskeletal infectionsLonger hospital stayOral antibiotic therapyRetrospective cohort studyTreatment-related complicationsTreatment-associated complicationsHospital stayPediatric infectionsCohort studyParenteral therapyTreatment complicationsIntensive careRecurrent infectionsWorse outcomes
2020
Nocardia veterana infections: case report and systematic review
Radcliffe C, Peaper D, Grant M. Nocardia veterana infections: case report and systematic review. New Microbes And New Infections 2020, 39: 100833. PMID: 33456780, PMCID: PMC7797559, DOI: 10.1016/j.nmni.2020.100833.Peer-Reviewed Case Reports and Technical NotesChronic cutaneous graftOral antibiotic therapySoft tissue abscessesHost diseaseCutaneous graftAntibiotic therapyPulmonary infectionCase reportDrainage proceduresEmpirical treatmentCondition warrantsSystematic reviewInfectionOpportunistic pathogenSystematic literature reviewFirst reportLiterature reviewReportAbscessRelapseReviewAzithromycinGraftTherapyNocardiaChallenges in the Diagnosis and Treatment of Lyme Disease
Schoen R. Challenges in the Diagnosis and Treatment of Lyme Disease. Current Rheumatology Reports 2020, 22: 3. PMID: 31912251, DOI: 10.1007/s11926-019-0857-2.Peer-Reviewed Original ResearchConceptsTreatment of Lyme diseaseClinical featuresCourse of oral antibiotic therapyOral antibiotic therapyLate-stage manifestationLate-stage diseaseLyme diseaseAntibiotic therapyCausative organismTreatment strategiesClinical expressionLyme arthritisImpact of Lyme diseaseDiagnosisDiseasePatientsTreatmentVector-borne illnessStrains of Borrelia burgdorferiLymeWell-characterizedMorbidityTherapyFindingsIt
2019
Actinomyces neuii: a case report of a rare cause of acute infective endocarditis and literature review
Yang WT, Grant M. Actinomyces neuii: a case report of a rare cause of acute infective endocarditis and literature review. BMC Infectious Diseases 2019, 19: 511. PMID: 31182045, PMCID: PMC6558687, DOI: 10.1186/s12879-019-4149-2.Peer-Reviewed Case Reports and Technical NotesConceptsInfective endocarditisActinomyces sppEnd-stage renal diseaseBilateral cerebral infarctsOral antibiotic therapyAcute infective endocarditisStage renal diseaseVulnerable patient populationBackgroundInfective endocarditisSeptic emboliValvular surgeryAcute presentationCerebral infarctsCase presentationAFacial droopAntibiotic therapyRenal diseaseRare causePatient populationCase reportClassic presentationConclusionsThis caseEndovascular infectionBlood culturesMonoclonal gammopathy
2006
Bacillus megaterium delayed onset lamellar keratitis after LASIK.
Ramos-Esteban JC, Servat JJ, Tauber S, Bia F. Bacillus megaterium delayed onset lamellar keratitis after LASIK. Journal Of Refractive Surgery 2006, 22: 309-12. PMID: 16602323, DOI: 10.3928/1081-597x-20060301-20.Peer-Reviewed Case Reports and Technical NotesConceptsAntibiotic therapyClinical presentationMicrobial keratitisRight eye 2 weeksEye 2 weeksFinal visual acuityInitial clinical presentationOral antibiotic therapyAggressive antibiotic therapyCorrection of myopiaAntibiotic prophylaxisAffected eyeInfectious etiologySymptomatic reliefVisual acuityRight eyeUnusual presentationBacterial cultureMicrobiologic investigationsUneventful LASIKTherapeutic elevationRefractive surgeryLASIK flapStromal bedAseptic technique
2001
Results of a Pilot Trial Comparing Prolonged Intravenous Antibiotics With Sequential Intravenous/Oral Antibiotics for Children With Perforated Appendicitis
Rice H, Brown R, Gollin G, Caty M, Gilbert J, Skinner M, Glick P, Azizkhan R. Results of a Pilot Trial Comparing Prolonged Intravenous Antibiotics With Sequential Intravenous/Oral Antibiotics for Children With Perforated Appendicitis. JAMA Surgery 2001, 136: 1391-1395. PMID: 11735866, DOI: 10.1001/archsurg.136.12.1391.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, OralAdolescentAmpicillinAppendicitisChildChild, PreschoolClavulanic AcidClindamycinDrug Administration ScheduleDrug Therapy, CombinationFemaleGentamicinsHumansInjections, IntravenousIntestinal PerforationMaleMetronidazolePilot ProjectsProspective StudiesRupture, SpontaneousConceptsNormal white blood cell countWhite blood cell countDuration of feverBlood cell countTreatment equivalenceIntravenous antibioticsOral antibioticsOral intakeOutcome measuresCell countShort courseProlonged intravenous antibioticsOral antibiotic therapyTertiary children's hospitalSecondary outcome measuresPrimary outcome measurePerforated appendicitisAntibiotic therapyChildren's HospitalMulticenter studyTherapy resultsClinical trialsPilot trialPatient chargesAppendicitis
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