2025
Spatial associations between alcohol detection in opioid overdose deaths and alcohol outlets
Viera A, Heimer R, Grau L. Spatial associations between alcohol detection in opioid overdose deaths and alcohol outlets. Drug And Alcohol Dependence 2025, 271: 112659. PMID: 40184870, PMCID: PMC12050193, DOI: 10.1016/j.drugalcdep.2025.112659.Peer-Reviewed Original ResearchConceptsOff-premise alcohol outletsNearest alcohol outletAlcohol outletsOpioid overdose deathsSpatial distribution of alcohol outletsSubstance use patternsDistribution of alcohol outletsDensity of alcohol outletsOverdose deathsDepressive effects of opioidsAlcohol outlet densityEffects of opioidsCensus tract levelAssociated with increased oddsOverdose riskCentral nervous systemOutlet densityTract levelCensus tractsDepressant effectCommunity investmentOpioidSocial vulnerabilityAlcoholNervous system
2024
An Urgent Need to Promote Equitable Buprenorphine Administration for Opioid Use Disorder in the Emergency Department
Coupet E, Edelman E. An Urgent Need to Promote Equitable Buprenorphine Administration for Opioid Use Disorder in the Emergency Department. Journal Of Addiction Medicine 2024, 19: 1-3. PMID: 39899674, DOI: 10.1097/adm.0000000000001409.Peer-Reviewed Original ResearchBuprenorphine administrationOpioid use disorder treatmentOpioid use disorderUse disorderAddiction treatmentDisorder treatmentEmergency departmentED patientsCross-sectional study of ED patientsTreatment accessBuprenorphineStudy of ED patientsOpioidOpioid overdose deathsOpioid misuseOverdose deathsCross-sectional studyLatinosAddictionImproving racial/ethnic health equity and naloxone access among people at risk for opioid overdose: A simulation modeling analysis of community‐based naloxone distribution strategies in Massachusetts, United States
Zang X, Skinner A, Li Z, Shaw L, Behrends C, Chatterjee A, Jalali A, Jordan A, Morgan J, Nolen S, Schackman B, Marshall B, Walley A. Improving racial/ethnic health equity and naloxone access among people at risk for opioid overdose: A simulation modeling analysis of community‐based naloxone distribution strategies in Massachusetts, United States. Addiction 2024, 120: 316-326. PMID: 39450522, PMCID: PMC11707306, DOI: 10.1111/add.16691.Peer-Reviewed Original ResearchRates of opioid overdose deathsOpioid overdose deathsEthnic disparitiesNaloxone availabilityHealth equityNaloxone distribution strategiesRacial/ethnic groupsHispanic/Latinx populationsHealthcare costsImprove overall population healthOverall population healthOverdose deathsRisk of opioid overdose deathCost per lifePopulation healthNaloxone kitsNaloxone accessSimulation model analysisOpioid overdoseDisparitiesIncremental costPopulation levelAnnual numberHealthcareEthnic groupsEvaluation of Strategies to Enhance Community-Based Naloxone Distribution Supported by an Opioid Settlement
Zang X, Skinner A, Krieger M, Behrends C, Park J, Green T, Walley A, Morgan J, Linas B, Yedinak J, Schackman B, Marshall B. Evaluation of Strategies to Enhance Community-Based Naloxone Distribution Supported by an Opioid Settlement. JAMA Network Open 2024, 7: e2413861. PMID: 38814644, PMCID: PMC11140538, DOI: 10.1001/jamanetworkopen.2024.13861.Peer-Reviewed Original ResearchConceptsCommunity-based naloxone distributionOpioid overdose deathsNaloxone distributionSolitary drug useOpioid overdoseNaloxone distribution programsDecision analytical model studyDrug useNonfatal opioid overdoseReducing opioid overdose deathsIncreasing naloxone distributionHypothetical interventionMain OutcomesNaloxone availabilityCommunity-based naloxone distribution programsStudy populationOverdose deathsInterventionAnnual numberUS statesMisuse opioidsAnalytical model studyRhode IslandPublished simulation modelSynergistic association
2023
Receipt of opioid use disorder treatments prior to fatal overdoses and comparison to no treatment in Connecticut, 2016–17
Heimer R, Black A, Lin H, Grau L, Fiellin D, Howell B, Hawk K, D'Onofrio G, Becker W. Receipt of opioid use disorder treatments prior to fatal overdoses and comparison to no treatment in Connecticut, 2016–17. Drug And Alcohol Dependence 2023, 254: 111040. PMID: 38043226, PMCID: PMC10872282, DOI: 10.1016/j.drugalcdep.2023.111040.Peer-Reviewed Original ResearchConceptsNon-medication treatmentsRelative riskOpioid overdose deathsIncidence rateMOUD treatmentOverdose deathsOpioid use disorder treatmentResults Incidence ratesRetrospective cohort studyDifferent treatment modalitiesPopulation-level effortsUse disorder treatmentFatal opioid poisoningsCohort studyOpioid poisoningTreatment modalitiesConclusion ExposurePoisoning deathsFatal overdosesTreatment exposureDisorder treatmentDeathTreatmentMethadoneRiskMortality, incarceration and cost implications of fentanyl felonization laws: A modeling study
Savinkina A, Jurecka C, Gonsalves G, Barocas J. Mortality, incarceration and cost implications of fentanyl felonization laws: A modeling study. International Journal Of Drug Policy 2023, 121: 104175. PMID: 37729682, PMCID: PMC10840895, DOI: 10.1016/j.drugpo.2023.104175.Peer-Reviewed Original ResearchChanges to opioid overdose deaths and community naloxone access among Black, Hispanic and White people from 2016 to 2021 with the onset of the COVID‐19 pandemic: An interrupted time‐series analysis in Massachusetts, USA
Zang X, Walley A, Chatterjee A, Kimmel S, Morgan J, Murphy S, Linas B, Nolen S, Reilly B, Urquhart C, Schackman B, Marshall B. Changes to opioid overdose deaths and community naloxone access among Black, Hispanic and White people from 2016 to 2021 with the onset of the COVID‐19 pandemic: An interrupted time‐series analysis in Massachusetts, USA. Addiction 2023, 118: 2413-2423. PMID: 37640687, PMCID: PMC10986189, DOI: 10.1111/add.16324.Peer-Reviewed Original ResearchConceptsNon-Hispanic black peopleRates of opioid overdose deathsNon-Hispanic whitesOpioid overdose deathsNaloxone kitsKit distributionOverdose deathsHispanic peopleNon-Hispanic White peopleNon-Hispanic blacksCommunity-based programsInterrupted time series analysisNaloxone kit distributionEthnic minority communitiesCOVID-19 pandemicWhite peopleOpioid overdose fatalitiesNaloxone distributionNaloxone accessNaloxone availabilityCOVID-19Black peoplePopulation groupsComplete dataMinority communitiesURINE TOXICOLOGY PROFILES OF EMERGENCY DEPARTMENT PATIENTS WITH UNTREATED OPIOID USE DISORDER: A MULTI-SITE VIEW
Cowan E, Perrone J, Dziura J, Edelman E, Hawk K, Herring A, McCormack R, Murphy A, Phadke M, Fiellin D, D'Onofrio G. URINE TOXICOLOGY PROFILES OF EMERGENCY DEPARTMENT PATIENTS WITH UNTREATED OPIOID USE DISORDER: A MULTI-SITE VIEW. Journal Of Emergency Medicine 2023, 65: e357-e365. PMID: 37716904, PMCID: PMC10591927, DOI: 10.1016/j.jemermed.2023.06.007.Peer-Reviewed Original ResearchUrine drug screensOpioid use disorderEmergency departmentUntreated opioid use disorderAdult ED patientsOpioid overdose deathsED patientsOnly opioidCommon opioidsOverdose deathsUse disordersCommon drugsOpioidsPolysubstance useDrug useDrug screensAmphetamine-type stimulantsFentanylPatientsAddiction treatmentStimulantsParticipantsBuprenorphineMethadoneBenzodiazepinesNational Institute on Drug Abuse Clinical Trials Network Meeting Report: Advancing Emergency Department Initiation of Buprenorphine for Opioid Use Disorder
Cowan E, Perrone J, Bernstein S, Coupet E, Fiellin D, Hawk K, Herring A, Huntley K, McCormack R, Venkatesh A, D'Onofrio G. National Institute on Drug Abuse Clinical Trials Network Meeting Report: Advancing Emergency Department Initiation of Buprenorphine for Opioid Use Disorder. Annals Of Emergency Medicine 2023, 82: 326-335. PMID: 37178101, PMCID: PMC10524880, DOI: 10.1016/j.annemergmed.2023.03.025.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsOpioid use disorderEmergency departmentUse disordersDrug Abuse Clinical Trials NetworkEffective evidence-based treatmentsEmergency department initiationStandard emergency careMajor public health crisisClinical Trials NetworkEvidence of efficacyNational InstituteEvidence-based treatmentsOpioid overdose deathsTechnology-based interventionsBuprenorphine dosingBuprenorphine initiationPeer-based interventionsPublic health crisisPatient outcomesED staffOverdose deathsEmergency careBuprenorphineTrials NetworkUniversal uptakeRacial and ethnic disparities in emergency department–initiated buprenorphine across five health care systems
Holland W, Li F, Nath B, Jeffery M, Stevens M, Melnick E, Dziura J, Khidir H, Skains R, D'Onofrio G, Soares W. Racial and ethnic disparities in emergency department–initiated buprenorphine across five health care systems. Academic Emergency Medicine 2023, 30: 709-720. PMID: 36660800, PMCID: PMC10467357, DOI: 10.1111/acem.14668.Peer-Reviewed Original ResearchConceptsOpioid use disorderCommunity emergency departmentsEmergency departmentDischarge diagnosisHealth care systemHispanic patientsBlack patientsHospital typeCare systemNon-Hispanic patientsOpioid overdose deathsClinical decision support systemOpioid withdrawalPrimary outcomeMedication treatmentBuprenorphine accessED treatmentTreatment accessOverdose deathsX-waiverBuprenorphinePatientsUse disordersEthnic disparitiesSecondary analysis
2022
Comparing Projected Fatal Overdose Outcomes and Costs of Strategies to Expand Community-Based Distribution of Naloxone in Rhode Island
Zang X, Bessey S, Krieger M, Hallowell B, Koziol J, Nolen S, Behrends C, Murphy S, Walley A, Linas B, Schackman B, Marshall B. Comparing Projected Fatal Overdose Outcomes and Costs of Strategies to Expand Community-Based Distribution of Naloxone in Rhode Island. JAMA Network Open 2022, 5: e2241174. PMID: 36350649, PMCID: PMC9647481, DOI: 10.1001/jamanetworkopen.2022.41174.Peer-Reviewed Original ResearchConceptsOpioid overdose death ratesOpioid overdose deathsDecision analytical model studyNaloxone kitsHealth inequalitiesNaloxone distributionOpioid overdoseRhode IslandCommunity-based programsCommunity-based organizationsDistribution of naloxoneMean incremental costAnalytical model studyState of Rhode IslandIncreasing naloxone distributionMain OutcomesPriority settingBetween-group varianceOutcomes of alternative strategiesDemand-based approachGeospatial inequalityMisused prescription opioidsCurrent population dataOverdose deathsPrescription opioids
2021
Simulating the impact of Addiction Consult Services in the context of drug supply contamination, hospitalizations, and drug-related mortality
King C, Cook R, Wheelock H, Korthuis P, Leahy J, Goff A, Morris C, Englander H. Simulating the impact of Addiction Consult Services in the context of drug supply contamination, hospitalizations, and drug-related mortality. International Journal Of Drug Policy 2021, 100: 103525. PMID: 34837879, PMCID: PMC8810590, DOI: 10.1016/j.drugpo.2021.103525.Peer-Reviewed Original ResearchConceptsAddiction consult serviceOpioid use disorderDrug-related deathsConsult serviceHospital dischargeCare systemDrug-related causesOpioid-related deathsDrug supplyRisk of overdoseDrug-related mortalityOpioid overdose deathsHarm reduction interventionsAdult patientsOUD patientsHospital admissionOpioid overdosesEffective treatmentOverdose deathsSimulated cohortPatientsUse disordersReduction interventionsHospitalizationDeathTargeting community-based naloxone distribution using opioid overdose death rates: A descriptive analysis of naloxone rescue kits and opioid overdose deaths in Massachusetts and Rhode Island
Zang X, Macmadu A, Krieger M, Behrends C, Green T, Morgan J, Murphy S, Nolen S, Walley A, Schackman B, Marshall B. Targeting community-based naloxone distribution using opioid overdose death rates: A descriptive analysis of naloxone rescue kits and opioid overdose deaths in Massachusetts and Rhode Island. International Journal Of Drug Policy 2021, 98: 103435. PMID: 34482264, PMCID: PMC8671216, DOI: 10.1016/j.drugpo.2021.103435.Peer-Reviewed Original ResearchConceptsOpioid overdose fatalitiesOpioid overdose deathsOpioid overdose death ratesNaloxone distributionOverdose deathsOEND programsOverdose death ratesOverdose fatalitiesNaloxone kitsDeath rateEffective public health interventionsNaloxone availabilityFatal opioid overdoseNaloxone rescue kitsNaloxone distribution programsPublic health interventionsHealth department dataMore urban countiesOpioid educationOpioid overdoseHealth interventionsRescue kitsNon-urban differencesDeathDepartment dataLow Threshold Telemedicine-based Opioid Treatment for Criminal Justice Involved Adults During the COVID-19 Pandemic: A Case Report
Flavin L, Tofighi B, Krawczyk N, Schatz D, McNeely J, Butner J. Low Threshold Telemedicine-based Opioid Treatment for Criminal Justice Involved Adults During the COVID-19 Pandemic: A Case Report. Journal Of Addiction Medicine 2021, 16: e59-e61. PMID: 35120069, PMCID: PMC8815634, DOI: 10.1097/adm.0000000000000836.Peer-Reviewed Original ResearchConceptsNew York City jailsCriminal justiceCity jailsEarly release programsOpioid use disorderOffice-based opioid treatment programSevere opioid use disorderCOVID-19 pandemicCounty jailPost-releaseBuprenorphine clinicUse disorderJailRelease programsRates of opioid overdose deathsBuprenorphine-naloxoneOpioid overdose deathsTreatment programsJusticeTemporary housingOverdose deathsBuprenorphine providersTele-conferencingCOVID-19Opioid treatment programsAn Evaluation of Opioid Use in Black Communities: A Rapid Review of the Literature.
Jordan A, Mathis M, Haeny A, Funaro M, Paltin D, Ransome Y. An Evaluation of Opioid Use in Black Communities: A Rapid Review of the Literature. Harvard Review Of Psychiatry 2021, 29: 108-130. PMID: 33666395, PMCID: PMC8335706, DOI: 10.1097/hrp.0000000000000285.Peer-Reviewed Original ResearchConceptsOpioid useRapid reviewSocial determinantsUse of opioidsTreatment-seeking patternsClear inclusion criteriaOpioid overdose deathsFull-text reviewComprehensive search strategyHealth care systemGrey literature sourcesClinician prescribingTreatment initiationInclusion criteriaOverdose deathsEpidemiologic SurveyClinical practiceHealth outcomesOpioid crisisOpioidsNarrative summaryTraditional health care systemCare systemSystematic review methodsBlack individualsProjected Estimates of Opioid Mortality After Community-Level Interventions
Linas BP, Savinkina A, Madushani RWMA, Wang J, Yazdi G, Chatterjee A, Walley AY, Morgan JR, Epstein RL, Assoumou SA, Murphy SM, Schackman BR, Chrysanthopoulou SA, White LF, Barocas JA. Projected Estimates of Opioid Mortality After Community-Level Interventions. JAMA Network Open 2021, 4: e2037259. PMID: 33587136, PMCID: PMC7885041, DOI: 10.1001/jamanetworkopen.2020.37259.Peer-Reviewed Original ResearchConceptsCommunity-level interventionsOverdose mortalityOpioid overdoseUse of MOUDDistribution of naloxoneOpioid overdose deathsDecision analytical modelOpioid overdose ratesMOUD retentionOUD populationOpioid mortalityMAIN OUTCOMEMOUDNaloxone distributionOverdose deathsOverdose ratesSingle interventionMortalityNaloxoneInterventionMonthsOverdoseProjected estimatesHuman ServicesOutcomesExpanding access to methadone treatment in Ohio through federally qualified health centers and a chain pharmacy: A geospatial modeling analysis
Iloglu S, Joudrey PJ, Wang EA, Thornhill TA, Gonsalves G. Expanding access to methadone treatment in Ohio through federally qualified health centers and a chain pharmacy: A geospatial modeling analysis. Drug And Alcohol Dependence 2021, 220: 108534. PMID: 33497963, PMCID: PMC7901120, DOI: 10.1016/j.drugalcdep.2021.108534.Peer-Reviewed Original ResearchConceptsFederally Qualified Health CentersOpioid treatment programsOpioid use disorderQualified health centersProportion of needHealth centersZip codesTreatment needsMethadone provisionChain pharmaciesRural-Urban Commuting Area codesProvision of methadoneOpioid overdose deathsRural classificationDrive timeMethadone administrationPrimary outcomeOUD treatmentMethadone treatmentUrban-rural strataOverdose deathsUse disordersTreatment programGeospatial modeling analysisOne-third
2020
Brief Report: Rates of Fentanyl Use Among Psychiatric Emergency Room Patients
Elmarasi M, Garcia‐Vassallo G, Campbell S, Fuehrlein B. Brief Report: Rates of Fentanyl Use Among Psychiatric Emergency Room Patients. American Journal On Addictions 2020, 30: 92-95. PMID: 32779217, DOI: 10.1111/ajad.13087.Peer-Reviewed Original ResearchConceptsUrine drug screensPsychiatric emergency roomFentanyl useEmergency roomPatient presentationUrine drug screening resultsDrug screensPsychiatric emergency room patientsPercent of patientsEmergency room patientsOpioid overdose deathsDrug screening resultsHarm reduction strategiesRates of fentanylVA ConnecticutRoom patientsRisk of fentanylBasic demographic informationOverdose deathsFentanylPatientsPsychiatric diagnosisOpioidsIllicit substancesEmergency populationBarriers to and recommendations for take-home naloxone distribution: perspectives from opioid treatment programs in New Mexico
Salvador J, Sussman A, Takeda M, Katzman W, Moya Balasch M, Katzman J. Barriers to and recommendations for take-home naloxone distribution: perspectives from opioid treatment programs in New Mexico. Harm Reduction Journal 2020, 17: 31. PMID: 32404109, PMCID: PMC7222293, DOI: 10.1186/s12954-020-00375-2.Peer-Reviewed Original ResearchConceptsTreatment program staffNaloxone distributionOpioid treatment programsTreatment programsOpioid overdose deathsFocus groupsProgram staffRates of opioid overdose deathsYear post-trainingFollow-up focus groupsOverdose deathsPolicy levelOpioid death ratesAssess current practiceLifesaving medicationsPatient receptivityPost-trainingBaseline surveyNaloxone trainingStaff timeReverse opioid overdoseCost of naloxoneIncrease accessTreatment settingsOpioid overdosePharmacy-based methadone dispensing and drive time to methadone treatment in five states within the United States: A cross-sectional study
Joudrey PJ, Chadi N, Roy P, Morford KL, Bach P, Kimmel S, Wang EA, Calcaterra SL. Pharmacy-based methadone dispensing and drive time to methadone treatment in five states within the United States: A cross-sectional study. Drug And Alcohol Dependence 2020, 211: 107968. PMID: 32268248, PMCID: PMC7529685, DOI: 10.1016/j.drugalcdep.2020.107968.Peer-Reviewed Original ResearchOpioid treatment programsMethadone accessOpioid use disorderCross-sectional studyOpioid overdose deathsCensus tractsDrive timeRural census tractsMethadone treatmentOverdose deathsUse disordersLong drive timesMethadoneTreatment programChain pharmaciesTractMedian differenceRural censusHigh ratePharmacyMedianUnited StatesPopulation
This site is protected by hCaptcha and its Privacy Policy and Terms of Service apply