2023
Understanding Regional Patterns of Overdose Deaths Related to Opioids and Psychostimulants
Segel J, Shearer R, Jones A, Khatri U, Howell B, Crowley D, Sterner G, Vest N, da Silva D, Winkelman T. Understanding Regional Patterns of Overdose Deaths Related to Opioids and Psychostimulants. Substance Use & Misuse 2023, 59: 558-566. PMID: 38037904, PMCID: PMC10923074, DOI: 10.1080/10826084.2023.2287220.Peer-Reviewed Original ResearchOverdose mortalityHigh opioidCross-sectional observational studyOverdose mortality ratesOverdose patternsConcurrent opioidIndex percentileObservational studyOpioidsOverdose ratesUnadjusted modelsOverdose deathsMortality filesMortality rateDisease preventionPercentage point increaseSVI scoresMortalityOverdose crisisPsychostimulantsMultiple substancesTreatment planningSubstantial regional variationPoint increaseAccess center
2021
Emergency Department Visits for Nonfatal Opioid Overdose During the COVID-19 Pandemic Across Six US Health Care Systems
Soares WE, Melnick ER, Nath B, D'Onofrio G, Paek H, Skains RM, Walter LA, Casey MF, Napoli A, Hoppe JA, Jeffery MM. Emergency Department Visits for Nonfatal Opioid Overdose During the COVID-19 Pandemic Across Six US Health Care Systems. Annals Of Emergency Medicine 2021, 79: 158-167. PMID: 34119326, PMCID: PMC8449788, DOI: 10.1016/j.annemergmed.2021.03.013.Peer-Reviewed Original ResearchConceptsHealth care systemCause ED visitsNonfatal opioid overdoseED visitsOpioid use disorderCare systemOpioid overdoseUse disordersCOVID-19 pandemicOpioid-related complicationsEmergency department visitsHospital-based interventionsED visit ratesEmergency department utilizationVisit countsUS health care systemOpioid overdose ratesDepartment visitsHistorical controlsAdult visitsOpioid overdosesOverdose ratesMedical emergencyVisit ratesMore weeksProjected Estimates of Opioid Mortality After Community-Level Interventions
Linas BP, Savinkina A, Madushani RWMA, Wang J, Yazdi G, Chatterjee A, Walley AY, Morgan JR, Epstein RL, Assoumou SA, Murphy SM, Schackman BR, Chrysanthopoulou SA, White LF, Barocas JA. Projected Estimates of Opioid Mortality After Community-Level Interventions. JAMA Network Open 2021, 4: e2037259. PMID: 33587136, PMCID: PMC7885041, DOI: 10.1001/jamanetworkopen.2020.37259.Peer-Reviewed Original ResearchConceptsCommunity-level interventionsOverdose mortalityOpioid overdoseUse of MOUDDistribution of naloxoneOpioid overdose deathsDecision analytical modelOpioid overdose ratesMOUD retentionOUD populationOpioid mortalityMAIN OUTCOMEMOUDNaloxone distributionOverdose deathsOverdose ratesSingle interventionMortalityNaloxoneInterventionMonthsOverdoseProjected estimatesHuman ServicesOutcomes
2020
Engagement in Harm Reduction Strategies After Suspected Fentanyl Contamination Among Opioid-Dependent Individuals
Mistler CB, Chandra DK, Copenhaver MM, Wickersham JA, Shrestha R. Engagement in Harm Reduction Strategies After Suspected Fentanyl Contamination Among Opioid-Dependent Individuals. Journal Of Community Health 2020, 46: 349-357. PMID: 32997253, PMCID: PMC7920905, DOI: 10.1007/s10900-020-00928-3.Peer-Reviewed Original ResearchConceptsFentanyl contaminationHarm reduction strategiesOpioid-dependent PWIDHigh-risk populationOpioid-dependent individualsHarm reduction behaviorsMethadone maintenance programHarm reduction methodsOpioid-related overdosesOverdose death ratesCross-sectional surveyDrug use behaviorsHarm reduction measuresPWID engagementMultivariable analysisFentanyl exposureOpioid epidemicOverdose ratesSynthetic opioidsDeath ratePolysubstance usersIntervention strategiesDrugsEvidence-based understandingEpidemicWhen Epidemics Collide: Coronavirus Disease 2019 (COVID-19) and the Opioid Crisis
Becker WC, Fiellin DA. When Epidemics Collide: Coronavirus Disease 2019 (COVID-19) and the Opioid Crisis. Annals Of Internal Medicine 2020, 173: m20-1210. PMID: 32240291, PMCID: PMC7138333, DOI: 10.7326/m20-1210.Peer-Reviewed Original Research
2019
Suspected heroin-related overdoses incidents in Cincinnati, Ohio: A spatiotemporal analysis
Li ZR, Xie E, Crawford FW, Warren JL, McConnell K, Copple JT, Johnson T, Gonsalves GS. Suspected heroin-related overdoses incidents in Cincinnati, Ohio: A spatiotemporal analysis. PLOS Medicine 2019, 16: e1002956. PMID: 31714940, PMCID: PMC6850525, DOI: 10.1371/journal.pmed.1002956.Peer-Reviewed Original ResearchConceptsRisk of overdoseRisk of incidentBlock groupHarm reduction measuresPoisson regression modelsHighest overdose ratesOpioid misuseRisk factorsOpioid epidemicOpiate overdosesOverdose incidentsOpioid overdosesOverdose ratesNature of incidentsEmergency callsMale populationMedian household incomeTreatment programOverdose emergencyHealth policySpatiotemporal risk factorsLack of informationDemographic characteristicsHigher numberOverdosesEmergency department visits for prescription and synthetic opioid overdoses among patients with cancer.
Jairam V, Yang D, Yu J, Park H. Emergency department visits for prescription and synthetic opioid overdoses among patients with cancer. Journal Of Clinical Oncology 2019, 37: 6579-6579. DOI: 10.1200/jco.2019.37.15_suppl.6579.Peer-Reviewed Original ResearchED visitsOpioid overdoseEmergency departmentHigh riskOverdose ratesCervical cancerSynthetic opioidsUtilization Project Nationwide Emergency Department SampleNationwide Emergency Department SampleNon-cancer patientsEnd Results ProgramEmergency Department SampleIntrahepatic bile ductsPrimary cancer siteSynthetic opioid overdoseDiagnosis of cancerRespiratory intubationMetastatic diseaseHospital admissionOpioid dependencePrimary cancerBile ductResults ProgramCancer patientsCommon cancer
2014
Trends and Regional Variation in Opioid Overdose Mortality Among Veterans Health Administration Patients, Fiscal Year 2001 to 2009
Bohnert AS, Ilgen MA, Trafton JA, Kerns RD, Eisenberg A, Ganoczy D, Blow FC. Trends and Regional Variation in Opioid Overdose Mortality Among Veterans Health Administration Patients, Fiscal Year 2001 to 2009. The Clinical Journal Of Pain 2014, 30: 605-612. PMID: 24281278, DOI: 10.1097/ajp.0000000000000011.Peer-Reviewed Original ResearchConceptsVeterans Health Administration patientsOpioid prescribingOverdose ratesNational Health SystemOverdose mortalityNational Death Index recordsHealth systemRate of overdosesPrescription opioid overdosesVeterans Health AdministrationOpioid overdose mortalityOpioid overdose deathsOverdose prevention strategiesPopulation-level associationPatient populationMedical recordsOpioid overdosesSemisynthetic opioidsOverdose deathsGeneral populationOpioid policyPrevention strategiesOpioidsHealth AdministrationPrescribing
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