2024
Peak Tricuspid Regurgitation Jet Velocity and Kidney Outcomes in Patients With Heart Failure With Preserved Ejection Fraction
Oka T, Tighiouart H, McCallum W, Tuttle M, Testani J, Sarnak M. Peak Tricuspid Regurgitation Jet Velocity and Kidney Outcomes in Patients With Heart Failure With Preserved Ejection Fraction. Kidney International Reports 2024, 9: 3035-3044. PMID: 39430198, PMCID: PMC11489825, DOI: 10.1016/j.ekir.2024.07.009.Peer-Reviewed Original ResearchLeft ventricular ejection fractionPulmonary artery pressureCreatinine doublingEGFR declineEjection fractionKidney outcomesHeart failurePeak tricuspid regurgitant jet velocityDoubling of serum creatinineTricuspid regurgitant jet velocityElevated pulmonary artery pressureAssociated with lower eGFRWorsening kidney functionVentricular ejection fractionRegurgitant jet velocityCox proportional hazards modelsProportional hazards modelPost Hoc AnalysisBaseline eGFRSerum creatinineLow eGFRTOPCAT trialFollow-upKidney functionArterial pressureCombined Genetic Association and Differed Expression Analysis of UBE2L3 Uncovers a Genetic Regulatory Role of (Immuno)proteasome in IgA Nephropathy
Xu L, Gan T, Li Y, Chen P, Shi S, Liu L, Lv J, Zhang H, Zhou X. Combined Genetic Association and Differed Expression Analysis of UBE2L3 Uncovers a Genetic Regulatory Role of (Immuno)proteasome in IgA Nephropathy. Kidney Diseases 2024, 10: 167-180. PMID: 38835407, PMCID: PMC11149991, DOI: 10.1159/000537987.Peer-Reviewed Original ResearchGd-IgA1IgA nephropathyHealthy controlsProteasome subunitsLevels of Gd-IgA1Genetic associationPeripheral blood mononuclear cellsExpression levelsEnd-stage renal diseaseSusceptibility to IgANBlood mononuclear cellsGd-IgA1 productionImmune cell typesBlood mRNA levelsFollow-up dataGalactose-deficient IgA1Cell typesUbiquitin-proteasome systemProcess of glycosylationPathogenesis of IgANAssociation of variantsDevelopment of IgANHigher proteinuriaLow eGFRHighest expression level
2020
Walking while Talking in Older Adults with Chronic Kidney Disease
Ho J, Verghese J, Abramowitz M. Walking while Talking in Older Adults with Chronic Kidney Disease. Clinical Journal Of The American Society Of Nephrology 2020, 15: 665-672. PMID: 32144098, PMCID: PMC7269215, DOI: 10.2215/cjn.12401019.Peer-Reviewed Original ResearchConceptsCognitive-motor interferenceDual-task costsWalking-while-talkingGait abnormalitiesGait speedSwing phaseAssociated with gait abnormalitiesQuantitative gait analysisCognitive-motor tasksLow eGFRGait domainsStance phaseGait analysisLinear spline regression modelsFactor analysisCommunity-dwellingOlder adultsRhythm domainNondisabled adultsGaitYears of ageSpline regression modelMultivariable adjustmentElderly populationCost domains
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