2025
Serum anti-mullerian hormone levels and age among Samoan women
O’Brien G, Lambert-Messerlian G, Hawley N, Fidow U, Naseri T, Reupena M, Kershaw E, Azar M, Pangburn M, McGarvey S. Serum anti-mullerian hormone levels and age among Samoan women. Reproductive Biology And Endocrinology 2025, 23: 45. PMID: 40108611, PMCID: PMC11921511, DOI: 10.1186/s12958-025-01379-y.Peer-Reviewed Original ResearchConceptsPCOS prevalencePolycystic ovary syndromeSerum anti-Mullerian hormoneAnti-Mullerian hormoneAnti-Mullerian hormone levelsSamoan womenAssociation of anti-Mullerian hormoneContraceptive useBody mass indexSerum anti-mullerian hormone levelsEthnic minority populationsHormonal contraceptive useAMH levelsAssociated with ageFree androgen indexMinority populationsSex hormone binding globulinReproductive healthAssociated with body mass indexSerum total testosteroneAndrogen indexPrevalence of obesityRelated declineTobacco useAdult women
2019
Association Between Levels of Sex Hormones and Risk of Esophageal Adenocarcinoma and Barrett’s Esophagus
Xie SH, Fang R, Huang M, Dai J, Thrift AP, Anderson LA, Chow WH, Bernstein L, Gammon MD, Risch HA, Shaheen NJ, Reid BJ, Wu AH, Iyer PG, Liu G, Corley DA, Whiteman DC, Caldas C, Pharoah PD, Hardie LJ, Fitzgerald RC, Shen H, Vaughan TL, Lagergren J. Association Between Levels of Sex Hormones and Risk of Esophageal Adenocarcinoma and Barrett’s Esophagus. Clinical Gastroenterology And Hepatology 2019, 18: 2701-2709.e3. PMID: 31756444, PMCID: PMC7580878, DOI: 10.1016/j.cgh.2019.11.030.Peer-Reviewed Original ResearchConceptsRisk of BERisk of EACBarrett's esophagusMendelian randomization analysisSex hormonesOdds ratioRandomization analysisSex hormone-binding globulinSpecific sex hormonesFree androgen indexFollicle-stimulating hormoneHormone-binding globulinGenetic risk scoreAndrogen indexDecreased riskEsophageal adenocarcinomaRisk scoreEsophagusAbstractTextLogistic regressionHormoneClear associationControl participantsGenetic factorsWomen
2018
Effect of exposure to second-hand smoke from husbands on biochemical hyperandrogenism, metabolic syndrome and conception rates in women with polycystic ovary syndrome undergoing ovulation induction
Li J, Wu Q, Wu XK, Zhou ZM, Fu P, Chen XH, Yan Y, Wang X, Yang ZW, Li WL, Stener-Victorin E, Legro RS, Ng EH, Zhang H, Mol BWJ, Wang CC, Group F. Effect of exposure to second-hand smoke from husbands on biochemical hyperandrogenism, metabolic syndrome and conception rates in women with polycystic ovary syndrome undergoing ovulation induction. Human Reproduction 2018, 33: 617-625. PMID: 29471520, DOI: 10.1093/humrep/dey027.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeNon-exposed womenSHS exposure statusSHS exposureMetabolic syndromeBiochemical hyperandrogenismObstetric outcomesOvary syndromeOvulation inductionSex hormonesExposure statusHigher serum total testosteroneSecond-hand smoke exposureSTUDY FUNDING/COMPETINGConception rateLower sex hormoneFree androgen indexSerum total testosteroneUterine blood flowLive birth rateNon-exposed groupSecond-hand smokePARTICIPANTS/MATERIALSROLE OF CHANCEAndrogen index
2017
Sexual function in infertile women with polycystic ovary syndrome and unexplained infertility
Diamond MP, Legro RS, Coutifaris C, Alvero R, Robinson RD, Casson PA, Christman GM, Huang H, Hansen KR, Baker V, Usadi R, Seungdamrong A, Bates GW, Rosen RM, Schlaff W, Haisenleder D, Krawetz SA, Barnhart K, Trussell JC, Santoro N, Eisenberg E, Zhang H, Network E. Sexual function in infertile women with polycystic ovary syndrome and unexplained infertility. American Journal Of Obstetrics And Gynecology 2017, 217: 191.e1-191.e19. PMID: 28455078, PMCID: PMC5657185, DOI: 10.1016/j.ajog.2017.04.034.Peer-Reviewed Original ResearchConceptsPolycystic ovary syndromeFemale Sexual Function InventoryUnexplained infertilityOvary syndromeSexual Function InventorySexual functionInfertile womenSexual dysfunctionEunice Kennedy Shriver National InstituteFemale Sexual Distress ScaleTotal scoreMultiple Intrauterine GestationsFree androgen indexReproductive-age womenSexual function scoresBody mass indexFemale sexual functionFemale sexual dysfunctionSexual Distress ScaleScale total scoreAndrogenic manifestationsAndrogen indexOvarian stimulationAndrogen excessIntrauterine gestationRacial and ethnic differences in the polycystic ovary syndrome metabolic phenotype
Engmann L, Jin S, Sun F, Legro RS, Polotsky AJ, Hansen KR, Coutifaris C, Diamond MP, Eisenberg E, Zhang H, Santoro N, Network R, Bartlebaugh C, Dodson W, Estes S, Gnatuk C, Ober J, Brzyski R, Easton C, Hernandez A, Leija M, Pierce D, Robinson R, Awonuga A, Cedo L, Cline A, Collins K, Krawetz S, Puscheck E, Singh M, Yoscovits M, Barnhart K, Lecks K, Martino L, Marunich R, Snyder P, Alvero R, Comfort A, Crow M, Schlaff W, Casson P, Hohmann A, Mallette S, Christman G, Ohl D, Ringbloom M, Tang J, Bates G, Mason S, DiMaria N, Usadi R, Lucidi R, Rhea M, Baker V, Turner K, Trussell J, DelBasso D, Huang H, Li Y, Makuch R, Patrizio P, Sakai L, Scahill L, Taylor H, Thomas T, Tsang S, Yan Q, Zhang M, Haisenleder D, Lamar C, DePaolo L, Guzick D, Herring A, Redmond J, Thomas M, Turek P, Wactawski-Wende J, Rebar R, Cato P, Dukic V, Lewis V, Schlegel P, Witter F. Racial and ethnic differences in the polycystic ovary syndrome metabolic phenotype. American Journal Of Obstetrics And Gynecology 2017, 216: 493.e1-493.e13. PMID: 28104402, PMCID: PMC5420474, DOI: 10.1016/j.ajog.2017.01.003.Peer-Reviewed Original ResearchConceptsPolycystic ovarian syndromeNon-Hispanic black womenNon-Hispanic whitesOvarian syndromeMetabolic syndromeNon-Hispanic blacksHispanic womenInsulin resistanceCardiovascular diseaseHigh prevalenceEthnic differencesType 2 diabetes mellitusLower serum triglyceride levelsNon-Hispanic white womenLower sex hormonePrevalence of hypertriglyceridemiaFree androgen indexHomeostasis model assessmentPolycystic ovary syndromeBody mass indexMetabolic phenotypeSerum triglyceride levelsType 2 diabetesBlack womenAndrogen index
2010
Predictors of Pregnancy in Women With Polycystic Ovary Syndrome
Rausch M, Legro R, Barnhart H, Schlaff W, Carr B, Diamond M, Carson S, Steinkampf M, McGovern P, Cataldo N, Gosman G, Nestler J, Giudice L, Leppert P, Myers E, Coutifaris C. Predictors of Pregnancy in Women With Polycystic Ovary Syndrome. Obstetrical & Gynecological Survey 2010, 65: 30-32. DOI: 10.1097/01.ogx.0000367515.48912.b1.Peer-Reviewed Original ResearchPolycystic ovary syndromeClomiphene citrateLive birthsOvary syndromeTreatment successCurrent first-line treatmentSelective estrogen receptor modulatorsBaseline patient characteristicsFirst-line treatmentFree androgen indexPredictors of pregnancyPrior pregnancy lossPrimary study outcomeBody mass indexInsulin sensitizer metforminEstrogen receptor modulatorsRelevant prognostic modelHirsutism scoreAndrogen indexGlucose intoleranceOvulation inductionPatient characteristicsPregnancy outcomesSmoking historyInfertile women
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