2024
Efficacy and Safety of Long-Acting Subcutaneous Lenacapavir in Heavily Treatment-Experienced People with Multidrug-Resistant HIV-1: Week 104 Results of a Phase 2/3 Trial
Ogbuagu O, Molina J, Chetchotisakd P, Ramgopal M, Sanchez W, Brunetta J, Castelli F, Crofoot G, Hung C, Ronot-Bregigeon S, Margot N, Wang H, Dvory-Sobol H, Rhee M, Segal-Maurer S. Efficacy and Safety of Long-Acting Subcutaneous Lenacapavir in Heavily Treatment-Experienced People with Multidrug-Resistant HIV-1: Week 104 Results of a Phase 2/3 Trial. Clinical Infectious Diseases 2024, 80: 566-574. PMID: 39206943, DOI: 10.1093/cid/ciae423.Peer-Reviewed Original ResearchMultidrug-resistant HIV-1Optimized background regimenHIV-1 RNA <CD4 cell countHIV-1Food & Drug AdministrationAdverse eventsTreatment of HIV-1 infectionRates of virologic suppressionCD4 cell count <Treatment-related adverse eventsMulti-drug resistant HIV-1Cell countTreatment-experienced peopleCell count <HIV-1 infectionHIV-1 RNAPhase 2/3 trialsImportant treatment optionInjection site reactionsResistant HIV-1US Food & Drug AdministrationBackground regimenVirologic suppressionStudy drug
2019
Treatment of Opioid Use Disorder in Pediatric Medical Settings
Levy S, Camenga D. Treatment of Opioid Use Disorder in Pediatric Medical Settings. Current Addiction Reports 2019, 6: 374-382. DOI: 10.1007/s40429-019-00272-0.ChaptersOpioid use disorderOpioid misusePediatric medical settingsChronic painUse disordersYoung adultsMedical settingsImportant treatment optionTreatment optionsOpioid epidemicSummaryMore researchReviewThe purposeBrief interventionDifferent interventionsPainTreatmentAdultsAdolescentsDisordersRecent findingsLong-term impactInterventionMisuseUpstream strategiesMedications
2016
Liposomal doxorubicin: Effective treatment for pediatric desmoid fibromatosis
Ananth P, Werger A, Voss S, Rodriguez‐Galindo C, Janeway KA. Liposomal doxorubicin: Effective treatment for pediatric desmoid fibromatosis. Pediatric Blood & Cancer 2016, 64: e26375. PMID: 27905688, DOI: 10.1002/pbc.26375.Peer-Reviewed Original ResearchConceptsProgression-free intervalLiposomal doxorubicinDesmoid fibromatosisLonger progression-free intervalMedian progression-free intervalRetrospective case seriesImportant treatment optionClinical responseMedical therapyCase seriesTumor sizeTreatment optionsEffective treatmentFibromatosisTreatmentChildrenMedications
2008
Surgical Treatment of Obstructive Sleep Apnea
Won CH, Li KK, Guilleminault C. Surgical Treatment of Obstructive Sleep Apnea. Annals Of The American Thoracic Society 2008, 5: 193-199. PMID: 18250212, DOI: 10.1513/pats.200708-121mg.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsObstructive sleep apneaPositive airway pressure therapySevere obstructive sleep apneaAirway pressure therapyRadiofrequency ablationMaxillomandibular advancementSleep apneaPressure therapyMaxillomandibular deficiencyUpper airway surgeryUpper airway obstructionImportant treatment optionLaser-assisted uvulopalatoplastyProper patient selectionImportant therapeutic considerationProper procedure selectionGenioglossal advancementRetrolingual obstructionUvulopalatal flapAirway obstructionNasal obstructionSurgical treatmentAirway surgeryPatient selectionMost surgeries
2006
Controversies in the treatment of gastroesophageal reflux and achalasia
Roberts K, Duffy A, Bell R. Controversies in the treatment of gastroesophageal reflux and achalasia. World Journal Of Gastroenterology 2006, 12: 3155-3161. PMID: 16718833, PMCID: PMC4087956, DOI: 10.3748/wjg.v12.i20.3155.Peer-Reviewed Original ResearchConceptsGastroesophageal reflux diseaseLaparoscopic antireflux surgeryTreatment optionsEffective treatmentPneumatic dilatationSurgical therapyEsophageal sphincterLaparoscopic surgeryTreatment of GERDObjective long-term resultsEffective non-surgical treatmentSecond treatment optionShorter hospital stayLaparoscopic Heller myotomyNon-surgical treatmentRisk of adenocarcinomaImportant treatment optionTreatment of achalasiaGold standardLong-term resultsNew treatment optionsExperienced laparoscopic surgeonsNon-invasive optionMinimal invasive surgeryPoor esophageal
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