2021
Signature of Enhanced Effector Function Defines Early Life Regulatory T Cells
Connors T, Bradley M, Verma S, Waldman E, Jang M, Grunstein E, Maurrasse S, Pethe K, Dogra P, Farber D. Signature of Enhanced Effector Function Defines Early Life Regulatory T Cells. The Journal Of Immunology 2021, 206: 98.27-98.27. DOI: 10.4049/jimmunol.206.supp.98.27.Peer-Reviewed Original ResearchRegulatory T cellsT cellsImmune responseEarly lifeGut-specific homingPrimary antigenic challengeIntestinal immune homeostasisConventional T cellsPotential effector mechanismsInflammatory immune responseEnhanced effector functionMulti-parameter flow cytometryAdult TregsImmunosuppressive mechanismsAntigenic challengeImmune homeostasisEffector mechanismsTregsImmune developmentEffector functionsSuppressive functionImmunological challengeHigh proliferative capacityCell cycleBulk RNA sequencing
2015
Lung Cancer Stem Cells
Woodard G, Jablons D. Lung Cancer Stem Cells. 2015, 199-225. DOI: 10.1007/978-3-319-21030-8_8.Peer-Reviewed Original ResearchLung cancer stem cellsCancer stem cellsLung cancerTherapeutic targetSmall cell lung cancerStem cellsCancer stem cell markersSquamous cell cancerCell lung cancerMultiple new drugsPromising therapeutic targetImportant therapeutic targetCell of originCancer stem cell hypothesisStem cell markersTumor resurgenceRecurrent diseaseCell cancerCancer mortalityClinical trialsNovel therapiesNew therapiesHigh proliferative capacitySmall molecule inhibitorsStem cell hypothesis
2003
Defining the Epithelial Stem Cell Niche in Skin
Tumbar T, Guasch G, Greco V, Blanpain C, Lowry WE, Rendl M, Fuchs E. Defining the Epithelial Stem Cell Niche in Skin. Science 2003, 303: 359-363. PMID: 14671312, PMCID: PMC2405920, DOI: 10.1126/science.1092436.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell CycleCell DivisionCell SeparationEpidermal CellsEpidermisEpithelial CellsGene Expression ProfilingGene Expression RegulationGreen Fluorescent ProteinsHair FollicleHistonesKeratinocytesLuminescent ProteinsMiceMice, TransgenicMicroscopy, FluorescenceMultipotent Stem CellsOligonucleotide Array Sequence AnalysisReverse Transcriptase Polymerase Chain ReactionRNA, MessengerTranscription, GeneticConceptsStem cell nicheLabel-retaining cellsCell nicheSkin stem cell nichesCell type-specific fashionType-specific fashionEpithelial stem cell nicheTranscriptional profilesSlow-cycling cellsHigh proliferative capacityMessenger RNANicheSurface receptorsProliferative capacityRegenerative cellsCellsRNAProgenyProtein
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