2024
Distinguishing vulnerability and resilience to posttraumatic stress disorder evaluating traumatic experiences, genetic risk and electronic health records
Løkhammer S, Koller D, Wendt F, Choi K, He J, Friligkou E, Overstreet C, Gelernter J, Hellard S, Polimanti R. Distinguishing vulnerability and resilience to posttraumatic stress disorder evaluating traumatic experiences, genetic risk and electronic health records. Psychiatry Research 2024, 337: 115950. PMID: 38744179, PMCID: PMC11156529, DOI: 10.1016/j.psychres.2024.115950.Peer-Reviewed Original ResearchElectronic health recordsPosttraumatic stress disorderHealth recordsPTSD vulnerabilityUK Biobank (UKBPhenome-wide association studyRisk scorePhenotype risk scoreUs Research ProgramPolygenic risk scoresStress disorderAoU participantsUKB participantsPresence of posttraumatic stress disorderTrauma burdenGenetic riskPosttraumatic stress disorder symptomsAssociation studiesPheWASClinical comorbiditiesComorbid associationsEye conditionsAOUInverse relationshipMultiple phenotypesElevating Ocular Diagnosis: Harnessing the Power of EfficientNet for Eye Disease Classification
Mohith V, Raja K, Oviya I. Elevating Ocular Diagnosis: Harnessing the Power of EfficientNet for Eye Disease Classification. 2024, 00: 1-6. DOI: 10.1109/aiiot58432.2024.10574627.Peer-Reviewed Original ResearchNeural network designDeep learning methodsMedical image processingAutomated diagnostic toolLearning methodsImage processingAccuracy rateField of ophthalmologyNetwork designHealthcare technologiesOverall accuracy rateSpectrum of medical conditionsDiabetic retinopathyOcular illnessEye conditionsTreatment planningDisease classificationMedical conditionsDiagnostic toolImprove patient careEfficientNetDiverse spectrumEyesPreprocessingTechnology integrationEmerging Co‐Assembled and Sustained Released Natural Medicinal Nanoparticles for Multitarget Therapy of Choroidal Neovascularization
Shen J, Chen L, Lv X, Liu N, Miao Y, Zhang Q, Xiao Z, Li M, Yang Y, Liu Z, Chen Q. Emerging Co‐Assembled and Sustained Released Natural Medicinal Nanoparticles for Multitarget Therapy of Choroidal Neovascularization. Advanced Materials 2024, 36: e2314095. PMID: 38344832, DOI: 10.1002/adma.202314095.Peer-Reviewed Original ResearchAge-related macular degenerationAnti-VEGFIntravitreal injectionAssociated with sight-threatening complicationsAnti-vascular endothelial growth factorAge-related macular degeneration treatmentFrequent intravitreal injectionsSight-threatening complicationsChoroidal neovascularization modelEndothelial growth factorInhibitor of angiogenesisChoroidal neovascularizationSubconjunctival injectionSubconjunctival administrationMacular degenerationNeovascularization modelImprove patient outcomesTherapeutic resultsEye conditionsInhibit angiogenesisQuality of lifeMultitarget therapyGrowth factorRabbit eyeballPatient outcomes
2020
Real-Time Eye-to-Eye Contact Is Associated With Cross-Brain Neural Coupling in Angular Gyrus
Noah JA, Zhang X, Dravida S, Ono Y, Naples A, McPartland JC, Hirsch J. Real-Time Eye-to-Eye Contact Is Associated With Cross-Brain Neural Coupling in Angular Gyrus. Frontiers In Human Neuroscience 2020, 14: 19. PMID: 32116606, PMCID: PMC7016046, DOI: 10.3389/fnhum.2020.00019.Peer-Reviewed Original ResearchTemporal-parietal junctionAngular gyrusEye contactRight temporal-parietal junctionNeural couplingInteractive behaviorDirect eye contactDynamic videosNeural processesNeural mechanismsEye gazeInterpersonal interactionsHuman participantsReal-time eyeSocial behaviorNeural signalsTime eyesFace videosGyrusTheoretical frameworkCoupling hypothesisGeneral theoretical frameworkParticipantsEye conditionsProcessing system
2013
Neural responses to fearful eyes in children with conduct problems and varying levels of callous–unemotional traits
Sebastian C, McCrory E, Dadds M, Cecil C, Lockwood P, Hyde Z, De Brito S, Viding E. Neural responses to fearful eyes in children with conduct problems and varying levels of callous–unemotional traits. Psychological Medicine 2013, 44: 99-109. PMID: 23510564, DOI: 10.1017/s0033291713000482.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingSubgenual anterior cingulate cortexImportant translational implicationsNeural responsesAnterior cingulate cortexAmygdala responseMagnetic resonance imagingFearful eyesConduct problemsTrial participantsEye conditionsCingulate cortexCortex responsesResonance imagingEvidence baseAmygdala reactivityTranslational implicationsHeterogeneous groupTD controlsEyesChildrenFear recognition deficitsNeural levelParticipantsLow levels
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