2025
Neonatal brain volumes and early parenting behavior as mediators in associations between prenatal social disadvantage and socioemotional problems in toddlers
Leverett S, Poolos O, Brady R, Tillman R, Lean R, Gerstein E, Anaya B, Triplett R, Alexopoulos D, Warner B, Luby J, Smyser C, Rogers C, Barch D. Neonatal brain volumes and early parenting behavior as mediators in associations between prenatal social disadvantage and socioemotional problems in toddlers. Biological Psychiatry 2025 PMID: 40414448, DOI: 10.1016/j.biopsych.2025.05.015.Peer-Reviewed Original ResearchNeonatal brain volumesAge 2 yearsEarly parenting behaviorsBrain volumeParenting behaviorsChildren aged 1 yearStructural magnetic resonance scansAge 1 yearMagnetic resonance scansSocioemotional difficultiesSocioemotional problemsBrain structural alterationsAssociated with increased externalizingChild socio-emotional problemsEarly risk factorsSocial disadvantageResonance scansRisk factorsMother-child dyadsSocio-emotional problemsPregnancyDysregulation symptomsExternalizing symptomsBrain metricsMediation model
2024
Associations between Parenting and Cognitive and Language Abilities at 2 Years of Age Depend on Prenatal Exposure to Disadvantage
Leverett S, Brady R, Tooley U, Lean R, Tillman R, Wilson J, Ruscitti M, Triplett R, Alexopoulos D, Gerstein E, Smyser T, Warner B, Luby J, Smyser C, Rogers C, Barch D. Associations between Parenting and Cognitive and Language Abilities at 2 Years of Age Depend on Prenatal Exposure to Disadvantage. The Journal Of Pediatrics 2024, 276: 114289. PMID: 39233119, PMCID: PMC11927132, DOI: 10.1016/j.jpeds.2024.114289.Peer-Reviewed Original ResearchConceptsAssociated with lower cognitionMother-child dyadsSubcortical gray matterLanguage abilityNonsupportive parentingEarly cognitionParenting behaviorsBrain volumeExposure to disadvantageSocial disadvantageNeonatal brain volumesLower cognitionBrain magnetic resonance imagingLevels of disadvantageMediation effectCognitionParental observationsModerating factorsAge 1 yearCognition/languageAge 2 yearsGray matterMagnetic resonance imagingObstetric clinicsPregnant women
2009
Clinical Implications for Patients With Long QT Syndrome Who Experience a Cardiac Event During Infancy
Spazzolini C, Mullally J, Moss AJ, Schwartz PJ, McNitt S, Ouellet G, Fugate T, Goldenberg I, Jons C, Zareba W, Robinson JL, Ackerman MJ, Benhorin J, Crotti L, Kaufman ES, Locati EH, Qi M, Napolitano C, Priori SG, Towbin JA, Vincent GM. Clinical Implications for Patients With Long QT Syndrome Who Experience a Cardiac Event During Infancy. Journal Of The American College Of Cardiology 2009, 54: 832-837. PMID: 19695463, PMCID: PMC3517782, DOI: 10.1016/j.jacc.2009.05.029.Peer-Reviewed Original ResearchConceptsSudden cardiac deathLong QT syndromeCardiac eventsQT syndromeHeart rateClinical implicationsFirst yearBeta-blocker therapyHigh-risk subsetInternational LQTS RegistryBeats/minAge 1 yearYears of lifeHazard ratioCardiac deathSyncopal episodesCardiac arrestLQTS RegistryFemale sexPrognostic aspectsQT intervalStudy populationHigh riskPatientsSyndrome
1996
Early presentation of metastatic medullary carcinoma in multiple endocrine neoplasia, type IIA: Implications for therapy
Gill J, Reyes-Múgica M, Iyengar S, Kidd K, Touloukian R, Smith C, Keller M, Genel M. Early presentation of metastatic medullary carcinoma in multiple endocrine neoplasia, type IIA: Implications for therapy. The Journal Of Pediatrics 1996, 129: 459-464. PMID: 8804341, DOI: 10.1016/s0022-3476(96)70084-7.Peer-Reviewed Original ResearchConceptsMedullary thyroid carcinomaMultiple endocrine neoplasiaEndocrine neoplasiaThyroid carcinomaMultifocal medullary thyroid carcinomaMetastatic medullary carcinomaElevated calcitonin levelsC-cell hyperplasiaType IIaAge 1 yearYears of ageYears 8 monthsYears 11 monthsIIA patientsLymph nodesCalcitonin levelsProphylactic thyroidectomyMedullary carcinomaStimulation testEarly presentationPositive findingsCarcinomaThyroidectomyNeoplasiaAge
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