Cognition in patients with mild autonomous cortisol secretion at baseline and post-adrenalectomy
Saini J, Nathani R, Singh S, Ebbehoj A, Thangamuthu K, Suresh M, Zhang C, Nevin S, Fell V, Atkinson E, Achenbach S, Stricker N, Bancos I. Cognition in patients with mild autonomous cortisol secretion at baseline and post-adrenalectomy. European Journal Of Endocrinology 2024, 191: 636-645. PMID: 39671564, PMCID: PMC11662234, DOI: 10.1093/ejendo/lvae157.Peer-Reviewed Original ResearchConceptsMild autonomous cortisol secretionReference subjectsT-scorePost-adrenalectomyBeck Depression InventoryComposite T-scoreAutonomous cortisol secretionSF-36Urine steroid profileImpact of adrenalectomyFrailty indexCross-sectional studyShort Form-36Longitudinal cohort studyNational Institutes of Health Toolbox Cognition BatteryCohort studyMultivariate analysisSteroid profileLower cognitionCortisol secretionPatientsAssociated with lower cognitionStandardized T scoresAdrenalectomyCognitive batteryAssociations between Parenting and Cognitive and Language Abilities at 2 Years of Age Depend on Prenatal Exposure to Disadvantage
Leverett S, Brady R, Tooley U, Lean R, Tillman R, Wilson J, Ruscitti M, Triplett R, Alexopoulos D, Gerstein E, Smyser T, Warner B, Luby J, Smyser C, Rogers C, Barch D. Associations between Parenting and Cognitive and Language Abilities at 2 Years of Age Depend on Prenatal Exposure to Disadvantage. The Journal Of Pediatrics 2024, 276: 114289. PMID: 39233119, PMCID: PMC11927132, DOI: 10.1016/j.jpeds.2024.114289.Peer-Reviewed Original ResearchConceptsAssociated with lower cognitionMother-child dyadsSubcortical gray matterLanguage abilityNonsupportive parentingEarly cognitionParenting behaviorsBrain volumeExposure to disadvantageSocial disadvantageNeonatal brain volumesLower cognitionBrain magnetic resonance imagingLevels of disadvantageMediation effectCognitionParental observationsModerating factorsAge 1 yearCognition/languageAge 2 yearsGray matterMagnetic resonance imagingObstetric clinicsPregnant women
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