2025
Dysregulated responses to stress and alcohol cues in cortico-striatal-limbic regions in social drinkers with early trauma
Heilner E, Sinha R, Eringros N, Constable R, Seo D. Dysregulated responses to stress and alcohol cues in cortico-striatal-limbic regions in social drinkers with early trauma. Journal Of Neural Transmission 2025, 1-16. PMID: 40500419, DOI: 10.1007/s00702-025-02961-9.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingAlcohol cuesEarly traumaSocial drinkersResponse to stressNeurobehavioral responses to stressDysregulated responses to stressNeutral cue exposureReward processing regionsReward-related disordersEmotional provocation taskPosterior cingulate cortexAlcohol-related disordersDecreased activityCraving ratingsDorsolateral PFCPrefrontal regulationAnterior PFCCue exposureReward processingEmotional reactivityPrefrontal regionsCingulate cortexNeural correlatesCue responsesInteracting immediate and long-term action regulation in suicidal behavior
Murphy N, Kypriotakis G, Lijffijt M, Iqbal S, Iqbal T, Amarneh D, O’Brien B, Tamman A, Thomas Y, Moukaddam N, Kosten T, Averill L, Mathew S, Swann A. Interacting immediate and long-term action regulation in suicidal behavior. Journal Of Mood And Anxiety Disorders 2025, 10: 100118. DOI: 10.1016/j.xjmad.2025.100118.Peer-Reviewed Original ResearchImmediate memory taskInternal State ScaleLifetime cumulative adversityChildhood traumaSuicidal behaviorAction regulationSuicidal ideationSuicide attemptsTreatment of suicide riskSSI-WConventional psychiatric diagnosesSevere suicide attemptsRegulation of actionsPsychiatric controlsMemory taskAddictive behaviorsPsychiatric diagnosisEarly traumaSuicide riskSuicidal crisisBehavioral symptomsStimulus discriminationCumulative adversityState scaleSuicideEpilogue: the formidable human need to “not know”
Amir D, Chefetz R, Costanzo A, Cundy P, Joiner T, Robison M, Şar V, Santoro G, Schimmenti A, Shahar G, Soffer-Dudek N, Somer E. Epilogue: the formidable human need to “not know”. 2025, 227-230. DOI: 10.4324/9781003560616-10.Peer-Reviewed Original ResearchObject relations theoristsTrait dissociationFragmentation of consciousnessDissociative patientsMaladaptive daydreamingEarly traumaMetapsychological frameworkSuicide attemptsPsychodynamic perspectiveExperiences of detachmentSubstance abuseDissociative phenomenaState dissociationPsychological dynamicsTherapeutic actionMentalPrimary correlateMainstream psychoanalysisRelations theoristsClinical fragmentsPsychotherapyClinical practiceEmpirical researchDaydreamingDepression
2024
A qualitative exploration of how adoptive parents experience the direct and indirect trauma of their child’s early maltreatment
Duncan M, Fearon P, Woolgar M. A qualitative exploration of how adoptive parents experience the direct and indirect trauma of their child’s early maltreatment. Adoption & Fostering 2024, 48: 167-183. DOI: 10.1177/03085759241251854.Peer-Reviewed Original ResearchChild-to-parent violenceEarly life traumaLevels of trauma symptomsSense of selfExperiences of adoptive parentsTraumatic early experiencesImpact of parentingTrauma symptomsLife traumaAdoptive parentsEarly traumaTrauma responseEarly experienceEmotional impactManaging challenging behaviourParent support networksNetwork of familyParents’ sense of selfChildren's previous experiencesChildren's early experiencesChallenging behaviorEarly maltreatmentTrauma experiencesRevised ImpactAdoption support groups
2023
Biological embedding of early trauma: the role of higher prefrontal synaptic strength
Tamman A, Jiang L, Averill C, Mason G, Averill L, Abdallah C. Biological embedding of early trauma: the role of higher prefrontal synaptic strength. European Journal Of Psychotraumatology 2023, 14: 2246338. PMID: 37642398, PMCID: PMC10467533, DOI: 10.1080/20008066.2023.2246338.Peer-Reviewed Original ResearchConceptsEarly traumaApproach/avoidance tendenciesReward responsivityAvoidance tendenciesBehavioral inhibitionSynaptic strengthPutative measurePhysical healthBiological embeddingHealthy controlsLarge human samplePTSDSynaptic processesGlutamatergic synaptic strengthPsychiatric disordersHigher EPCHuman samplesStudy findingsGlutamatergic excitotoxicityPharmacological treatmentDirect measureMeasuresTraumaEmotionsSynaptic plasticity
2018
Childhood trauma moderates inhibitory control and anterior cingulate cortex activation during stress
Zhai ZW, Yip SW, Lacadie CM, Sinha R, Mayes LC, Potenza MN. Childhood trauma moderates inhibitory control and anterior cingulate cortex activation during stress. NeuroImage 2018, 185: 111-118. PMID: 30342975, PMCID: PMC6392043, DOI: 10.1016/j.neuroimage.2018.10.049.Peer-Reviewed Original ResearchConceptsAnterior cingulate cortexStroop errorsInhibitory controlChildhood traumaStress reactivityStroop colour-word task performanceStroop color-word taskAnterior cingulate cortex activationColor-word taskInhibitory control processesRostral cingulate zoneFunctional magnetic resonanceHigh childhood traumaNeural correlatesTask performanceBrain activationSubjective anxietyACC activationAffective responsesCortex activationAddictive behaviorsEarly traumaStress cuesNeurodevelopmental changesCingulate cortex
2014
Co-Occurring Chronic Depression and Alcohol Dependence
Penberthy J, Gioia C, Konig A, Martin A, Cockrell S, Meshberg-Cohen S. Co-Occurring Chronic Depression and Alcohol Dependence. Addictive Disorders & Their Treatment 2014, 13: 54-67. DOI: 10.1097/adt.0b013e31827de84e.Peer-Reviewed Original ResearchAlcohol-dependent individualsChronic depressionAlcohol dependenceAlcohol intakeCo-occurring alcohol dependenceSuccessful treatment optionCognitive Behavioral Analysis SystemBehavioral Analysis SystemTreatment optionsCBASPBehavioral treatmentIndividual disordersDepressionDrinking levelsAvoidance learningTherapyHigh rateEarly traumaTreatmentIntakeDisordersIndividualsPopulationSymptomsTrauma
2005
A gender specific psychometric analysis of the early trauma inventory short form in cocaine dependent adults
Hyman SM, Garcia M, Kemp K, Mazure CM, Sinha R. A gender specific psychometric analysis of the early trauma inventory short form in cocaine dependent adults. Addictive Behaviors 2005, 30: 847-852. PMID: 15833587, PMCID: PMC2444015, DOI: 10.1016/j.addbeh.2004.08.009.Peer-Reviewed Original ResearchConceptsLifetime diagnosisDSM-IV Axis I DisordersMajor depressive disorderStructured Clinical InterviewAxis I DisordersCocaine-dependent adultsAlcohol use disorderCocaine-dependent menShort formChildhood Trauma Questionnaire-Short FormEarly traumaQuestionnaire-Short FormInternal consistencyClinical research toolDepressive disorderI disordersPredictive validityGood internal consistencyPsychiatric disordersUse disordersClinical InterviewDependent menCTQ-SFDependent adultsWomenMinding the Baby
Slade A, Sadler L, De Dios-Kenn C, Webb D, Currier-Ezepchick J, Mayes L. Minding the Baby. The Psychoanalytic Study Of The Child 2005, 60: 74-100. PMID: 16649676, DOI: 10.1080/00797308.2005.11800747.Peer-Reviewed Original Research
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