Test and treat approach for tuberculosis infection amongst household contacts of drug-susceptible pulmonary tuberculosis, Mumbai, India
Shah D, Bhide S, Deshmukh R, Smith J, Kaiplyawar S, Puri V, Yeldandi V, Date A, Nyendak M, Ho C, Moonan P. Test and treat approach for tuberculosis infection amongst household contacts of drug-susceptible pulmonary tuberculosis, Mumbai, India. Frontiers In Tuberculosis 2024, 2: 1454277. PMID: 39421397, PMCID: PMC11485165, DOI: 10.3389/ftubr.2024.1454277.Peer-Reviewed Original ResearchInterferon-gamma release assayTB preventive treatmentTB infectionHousehold contactsDrug-susceptible pulmonary tuberculosisTB diseaseTreat approachProgression to active TB diseaseDrug-susceptible pulmonary TBRate of TB infectionPrevalence of TB infectionActive TB diseaseAge 5 yearsSecondary TB casesCross-sectional studyAntituberculosis treatmentIGRA testPulmonary TBPulmonary tuberculosisTuberculosis infectionInterferon-gammaRelease assayClinical evaluationEarly diagnosisTreat strategyHealth-seeking behaviour and patient-related factors associated with the time to TB treatment initiation in four African countries: a cross-sectional survey
Sathar F, Charalambous S, Velen K, Fielding K, Rachow A, Ivanova O, Rassool M, Lalashowi J, Owolabi O, Nhassengo P, Chihota V, Evans D. Health-seeking behaviour and patient-related factors associated with the time to TB treatment initiation in four African countries: a cross-sectional survey. BMJ Public Health 2024, 2: e001002. PMID: 40018527, PMCID: PMC11816287, DOI: 10.1136/bmjph-2024-001002.Peer-Reviewed Original ResearchTB treatment initiationCross-sectional surveyTB symptomsPrimary care facilitiesTreatment initiationMedian total delayHealth-seeking behaviorNational TB Control ProgrammeTB treatmentCohort of adultsTB control programmesActive case findingPatient-related factorsHealth facilitiesTB servicesHIV prevalenceCare facilitiesDrug-susceptible pulmonary TBTotal delaySecond-leading causeTime to treatment initiationCase findingCox regression modelsStructured questionnaireInitiation of treatment
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