2025
Impact of age-related changes in buccal epithelial cells on pediatric epigenetic biomarker research
Merrill S, Konwar C, Fatima F, Dever K, MacIsaac J, Letourneau N, Giesbrecht G, Dewey D, England-Mason G, Lewis C, Wang D, Teh A, Meaney M, Gonzalez A, Noll J, De Weerth C, Bush N, O’Donnell K, Stewart S, Kobor M. Impact of age-related changes in buccal epithelial cells on pediatric epigenetic biomarker research. Nature Communications 2025, 16: 609. PMID: 39800776, PMCID: PMC11725590, DOI: 10.1038/s41467-025-55909-8.Peer-Reviewed Original ResearchConceptsBuccal epithelial cellsAge-related changesObsessive-compulsive disorderEpithelial cellsDiurnal cortisol slopeCheek swabsImpact of age-related changesCortisol slopeAssociated with ageOral cellsDevelopmental rangeAge accelerationDNA methylation studiesHeterogeneous sampleNeutrophil proportionBiomarker researchMethylation studiesAgeSwabsWeak associationEpigenetic age
2024
The Interactive Effects of Rejection and Rumination on Diurnal Cortisol among Adolescent Girls: A Preliminary Daily Diary Study
Vergara-Lopez C, Scalco M, Gaffey A, Reid B, Bublitz M, Lee S, Gomez A, Mercado N, Stroud L. The Interactive Effects of Rejection and Rumination on Diurnal Cortisol among Adolescent Girls: A Preliminary Daily Diary Study. Cognitive Therapy And Research 2024, 48: 1027-1034. PMID: 39359256, PMCID: PMC11444640, DOI: 10.1007/s10608-024-10492-y.Peer-Reviewed Original ResearchDiurnal cortisol slopePerseverative cognition hypothesisCortisol awakening responseWaking cortisol levelsSocial rejectionEffects of rejectionCortisol slopeDiurnal cortisolAwakening responseCognition hypothesisBlunted diurnal cortisol slopeEffects of social rejectionExperience of social rejectionSaliva samples 4 timesFlatter diurnal cortisol slopesDaily diary studyDaily diary reportsCortisol levelsAbsence of ruminationStress physiologyAdolescent girlsInteraction effectsPsychiatric riskCognitive mechanismsDiary reports
2022
Real-time racial discrimination, affective states, salivary cortisol and alpha-amylase in Black adults
Nam S, Jeon S, Lee SJ, Ash G, Nelson LE, Granger DA. Real-time racial discrimination, affective states, salivary cortisol and alpha-amylase in Black adults. PLOS ONE 2022, 17: e0273081. PMID: 36103465, PMCID: PMC9473392, DOI: 10.1371/journal.pone.0273081.Peer-Reviewed Original ResearchConceptsAutonomic nervous systemEcological momentary assessmentDiurnal slopeCortisol levelsPhysiological stress responseBlack adultsMajor stress response systemsHealthy black adultsFlatter diurnal slopeDiurnal cortisol slopeNervous systemSalivary biomarkersHealth outcomesLarger sample sizeCortisol slopeSalivary cortisolConcurrent useBaseline surveyStress response systemStress responseCross-sectional dataCortisolSame dayFurther studiesAlpha-amylase
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