2024
Heat and Cardiovascular Mortality: An Epidemiological Perspective
Singh N, Areal A, Breitner S, Zhang S, Agewall S, Schikowski T, Schneider A. Heat and Cardiovascular Mortality: An Epidemiological Perspective. Circulation Research 2024, 134: 1098-1112. PMID: 38662866, PMCID: PMC11042530, DOI: 10.1161/circresaha.123.323615.Peer-Reviewed Original ResearchConceptsCardiovascular disease mortalityCardiovascular disease deathsCVD deathHealth professionalsCardiovascular diseaseEpidemiological studiesAssociated with CVD mortalityMeta-analyses of epidemiological studiesEpidemiological evidenceCause-specific deathMiddle-income countriesAll-Cause MortalityCVD mortalityLack of evidenceEnvironmental epidemiologyInteractive effects of heatOlder peoplePotential biological pathwaysVulnerable subgroupsSystematic reviewMeta-analysesRobust evidenceHealth effectsPreexisting conditionsHealth
2023
Racial/ethnic disparities in PM2.5-attributable cardiovascular mortality burden in the United States
Ma Y, Zang E, Opara I, Lu Y, Krumholz H, Chen K. Racial/ethnic disparities in PM2.5-attributable cardiovascular mortality burden in the United States. Nature Human Behaviour 2023, 7: 2074-2083. PMID: 37653149, PMCID: PMC10901568, DOI: 10.1038/s41562-023-01694-7.Peer-Reviewed Original ResearchConceptsNon-Hispanic White peopleCVD deathMortality burdenNon-Hispanic black peopleCardiovascular disease mortality ratesDisease mortality ratesNon-Hispanic blacksRace/ethnicityMortality rateLong-term exposureWhite peopleEthnic disparitiesHealth benefitsHispanic peopleSignificant differencesBurdenDeathUS countiesEthnic groupsAbsolute disparityAssociationExposureEthnic minoritiesDisparitiesAmbient fine particulate matter (PM2.5) concentrations
2021
Cardiotoxic safety communications after FDA approval of novel cancer therapies.
Bonsu J, Kola-Kehinde O, Kim L, Ruz P, Lustberg M, Brammer J, Addison D. Cardiotoxic safety communications after FDA approval of novel cancer therapies. Journal Of Clinical Oncology 2021, 39: e18629-e18629. DOI: 10.1200/jco.2021.39.15_suppl.e18629.Peer-Reviewed Original ResearchBlack box warningNovel anticancer therapiesHeart failureNovel cancer therapiesThromboembolic diseaseBox warningCancer therapyCardiovascular disease eventsAnticancer therapyMultivariable logistic regressionSudden cardiac deathApproval statusNew safety informationPriority review statusUncontrolled hypertensionCVD eventsCardiac deathCoronary diseaseCVD deathDrug withdrawalElectrocardiographic changesMyocardial infarctionDrug classesLabel warningsMultivariable model
2020
Integrating HIV pre‐exposure prophylaxis and harm reduction among men who have sex with men and transgender women to address intersecting harms associated with stimulant use: a modelling study
Bórquez A, Rich K, Farrell M, Degenhardt L, McKetin R, Tran LT, Cepeda J, Silva‐Santisteban A, Konda K, Cáceres CF, Kelly S, Altice FL, Martin NK. Integrating HIV pre‐exposure prophylaxis and harm reduction among men who have sex with men and transgender women to address intersecting harms associated with stimulant use: a modelling study. Journal Of The International AIDS Society 2020, 23: e25495. PMID: 32562365, PMCID: PMC7305413, DOI: 10.1002/jia2.25495.Peer-Reviewed Original ResearchConceptsMSM/transgender womenHIV pre-exposure prophylaxisPre-exposure prophylaxisNew HIV infectionsHIV infectionTransgender womenStimulant useCVD mortalityCVD deathHealth harmsIntegrated substance useMore HIV infectionsHigh HIV incidenceCardiovascular disease mortalityRandom allocationUnprotected anal sexRisk of suicideHIV incidenceHIV transmissionDisease mortalityHIV riskGlobal systematic reviewAnal sexReduction interventionsSystematic review
2016
Sick Populations and Sick Subpopulations
Lu Y, Ezzati M, Rimm EB, Hajifathalian K, Ueda P, Danaei G. Sick Populations and Sick Subpopulations. Circulation 2016, 134: 472-485. PMID: 27324491, PMCID: PMC5001154, DOI: 10.1161/circulationaha.115.018102.Peer-Reviewed Original ResearchConceptsMultiple risk factorsCVD death ratesHigh-risk individualsRisk factorsNonfatal CVDCVD riskCVD deathFatal CVDDeath rateRisk-based interventionsWhite menCVD ratesNutrition Examination Survey 1999Cardiovascular disease death ratesWhite womenRacial disparitiesRisk of CVDExamination Survey 1999Black-white differencesDisease death ratesYears of ageBlack womenBlack menSick populationNational Health
2011
Cardiovascular disease: the new epidemic in sub-Saharan Africa
Ikem I, Sumpio BE. Cardiovascular disease: the new epidemic in sub-Saharan Africa. Vascular 2011, 19: 301-307. PMID: 21940758, DOI: 10.1258/vasc.2011.ra0049.Peer-Reviewed Original ResearchConceptsCVD risk factorsRisk factorsCurrent human immunodeficiency virus (HIV) epidemicHuman immunodeficiency virus (HIV) epidemicDouble burdenNew epidemicCardiovascular disease preventionCoronary heart diseasePrevalence of CVDCause of deathNon-communicable diseasesHIV/CVD deathImmunodeficiency syndromeCVD diseaseEpidemiological shiftHeart diseaseSmoking ratesDisease preventionCurrent epidemicDiseaseVirus epidemicDiabetesEpidemicHigh rate
2003
Mitral Annular Calcification Predicts Cardiovascular Morbidity and Mortality
Fox C, Vasan R, Parise H, Levy D, O’Donnell C, D’Agostino R, Benjamin E. Mitral Annular Calcification Predicts Cardiovascular Morbidity and Mortality. Circulation 2003, 107: 1492-1496. PMID: 12654605, DOI: 10.1161/01.cir.0000058168.26163.bc.Peer-Reviewed Original ResearchConceptsMitral annular calcificationIncident CVDCVD deathCause deathAnnular calcificationHazard ratioPresence of MACIncident CVD eventsIncidence of CVDCardiovascular disease outcomesFramingham Heart Study subjectsMultivariable adjusted analysesSmall retrospective studiesCommunity-based cohortM-mode echocardiographyProportional hazards modelCardiovascular morbidityCVD eventsCVD morbidityCVD riskEchocardiographic assessmentAdjusted analysisRetrospective studyProspective dataIndependent association
2002
Three-Dimensional Cardiovascular Image Analysis
Frangi A, Rueckert D, Duncan JS. Three-Dimensional Cardiovascular Image Analysis. IEEE Transactions On Medical Imaging 2002, 21: 1005. PMID: 12564868, DOI: 10.1109/tmi.2002.804442.Peer-Reviewed Original Research
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