2023
A novel non-invasive colorectal cancer diagnostic method: Volatile organic compounds as biomarkers
Alustiza M, Ripoll L, Canals A, Murcia O, Martínez-Roca A, García-Heredia A, Giner-Calabuig M, Jover R, Vidal L. A novel non-invasive colorectal cancer diagnostic method: Volatile organic compounds as biomarkers. Clinica Chimica Acta 2023, 542: 117273. PMID: 36863694, DOI: 10.1016/j.cca.2023.117273.Peer-Reviewed Original ResearchConceptsVolatile organic compoundsOrganic compoundsPre-malignant lesionsThermal desorption-gas chromatography-mass spectrometryFecal testsP-cresolSensitive analytical methodologyCancer samplesColorectal cancer screeningChromatography-mass spectrometryMagnetic graphene oxideCRC patient samplesFecal samplesExtractant phaseSpecificity 63Cancer screeningStool samplesAdenomatous polypsCRC detectionGraphene oxideSpecificity 79Adsorptive extractionSensitivity 83Analytical methodologyPatient samples
2021
Clip Closure Does Not Reduce Risk of Bleeding After Resection of Large Serrated Polyps: Results From a Randomized Trial
Crockett S, Khashab M, Rex D, Grimm I, Moyer M, Rastogi A, Mackenzie T, Pohl H, Consortium L, Al-Kawas F, Antaki F, Aslanian H, Crockett S, Elias P, Elmunzer B, Gill J, Gordon S, Grimm I, Hasan M, Khashab M, Law R, Levenick J, Mackenzie T, Mathew A, Moyer M, Ortiz O, Pellise M, Pleskow D, Pohl H, Rastogi A, von Renteln D, Rex D, Sanaei O. Clip Closure Does Not Reduce Risk of Bleeding After Resection of Large Serrated Polyps: Results From a Randomized Trial. Clinical Gastroenterology And Hepatology 2021, 20: 1757-1765.e4. PMID: 34971811, DOI: 10.1016/j.cgh.2021.12.036.Peer-Reviewed Original ResearchConceptsLarge serrated polypsEndoscopic mucosal resectionPost-procedure bleedingAdenomatous polypsBleeding rateProximal colonSerrated polypsControl groupLarge non-pedunculated polypsLimited clinical trial evidenceOverall serious adverse eventsPost-polypectomy bleeding rateDay of colonoscopyNon-pedunculated polypsSerious adverse eventsClinical trial evidenceRisk of bleedingColorectal cancer precursorsResection baseBleeding riskAdverse eventsMucosal resectionMulticenter trialPrimary outcomeProphylactic clipping
2016
Colorectal Cancer with Residual Polyp of Origin: A Model of Malignant Transformation
Druliner B, Rashtak S, Ruan X, Bae T, Vasmatzis N, O’Brien D, Johnson R, Felmlee-Devine D, Washechek-Aletto J, Basu N, Liu H, Smyrk T, Abyzov A, Boardman L. Colorectal Cancer with Residual Polyp of Origin: A Model of Malignant Transformation. Translational Oncology 2016, 9: 280-286. PMID: 27567950, PMCID: PMC4941582, DOI: 10.1016/j.tranon.2016.06.002.Peer-Reviewed Original ResearchColorectal cancerResidual polypBiopsy-proven colorectal cancerEquivalent hazard ratiosEarly-stage diseaseSame disease stageRemnant polypsHazard ratioOverall survivalCancer Genome AtlasClinical coursePathologic characteristicsDisease stageMayo ClinicAdenomatous polypsColorectal carcinogenesisMalignant transformationCarcinoma transitionPolypsGenome AtlasGene expression profilesGenomic profilesWhole-genome sequencingCancerAge
2006
Chemoprevention of Second Cancers
Mayne ST, Cartmel B. Chemoprevention of Second Cancers. Cancer Epidemiology Biomarkers & Prevention 2006, 15: 2033-2037. PMID: 17057027, DOI: 10.1158/1055-9965.epi-06-0415.Peer-Reviewed Original ResearchConceptsSecond cancersSubgroup effectsTobacco-related cancersColorectal adenomatous polypsObservational epidemiologic studiesPrimary cancerSmoking statusTumor characteristicsFuture trialsCancer sitesLifestyle habitsChemopreventive efficacyBreast cancerSecondary cancersAdenomatous polypsEpidemiologic studiesChemopreventive agentsAlcohol consumptionSkin cancerNutritional statusChemopreventionCancerGenetic susceptibilityCancer treatmentTrial results
2005
Differential Features of Colorectal Cancers Fulfilling Amsterdam Criteria without Involvement of the Mutator Pathway
Llor X, Pons E, Xicola RM, Castells A, Alenda C, Piñol V, Andreu M, Castellví-Bel S, Payá A, Jover R, Bessa X, Girós A, Roca A, Gassull MA, Association F. Differential Features of Colorectal Cancers Fulfilling Amsterdam Criteria without Involvement of the Mutator Pathway. Clinical Cancer Research 2005, 11: 7304-7310. PMID: 16243801, DOI: 10.1158/1078-0432.ccr-05-0965.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAgedAged, 80 and overCarrier ProteinsCohort StudiesColorectal NeoplasmsColorectal Neoplasms, Hereditary NonpolyposisDNA Mutational AnalysisDNA-Binding ProteinsFemaleGerm-Line MutationHumansImmunohistochemistryMaleMicrosatellite RepeatsMiddle AgedMutationMutL Protein Homolog 1MutS Homolog 2 ProteinNuclear ProteinsProspective StudiesSpainConceptsHereditary nonpolyposis colorectal cancerHNPCC patientsAmsterdam criteriaColorectal cancerPathway alterationsMicrosatellite instabilityMetachronous adenomatous polypsLeft-sided tumorsMismatch repair gene mutationsAmsterdam II criteriaColorectal cancer patientsNonpolyposis colorectal cancerRepair gene mutationsMismatch repair deficiencyDetailed family historyMMR alterationsEndometrial cancerLymphocytic infiltratePathologic dataCancer patientsFamily historyAdenomatous polypsHNPCC familiesPatientsTumor DNA
1995
Differences in laser-induced autofluorescence between adenomatous and hyperplastic polyps and normal colonic mucosa by confocal microscopy
Fiarman G, Nathanson M, Brian West A, Deckelbaum L, Kelly L, Kapadia C. Differences in laser-induced autofluorescence between adenomatous and hyperplastic polyps and normal colonic mucosa by confocal microscopy. Digestive Diseases And Sciences 1995, 40: 1261-1268. PMID: 7781444, DOI: 10.1007/bf02065535.Peer-Reviewed Original Research
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