1998
Patch clamp recording from the intact dorsal root ganglion
Zhang J, Donnelly D, LaMotte R. Patch clamp recording from the intact dorsal root ganglion. Journal Of Neuroscience Methods 1998, 79: 97-103. PMID: 9531465, DOI: 10.1016/s0165-0270(97)00164-7.Peer-Reviewed Original ResearchConceptsPatch-clamp recordingsConduction velocityAction potentialsSciatic nerveC cellsIntact dorsal root gangliaDorsal root ganglion cellsDorsal root gangliaAxonal conduction velocityGanglion sheathL5 DRGDRG cellsRoot gangliaGanglion cellsAP thresholdBeta cellsClamp recordingsSodium currentAdeltaCurrent clampConnective tissueVoltage clampNerveGangliaTTX
1997
Axotomy Increases the Excitability of Dorsal Root Ganglion Cells With Unmyelinated Axons
Zhang J, Donnelly D, Song X, Lamotte R. Axotomy Increases the Excitability of Dorsal Root Ganglion Cells With Unmyelinated Axons. Journal Of Neurophysiology 1997, 78: 2790-2794. PMID: 9356426, DOI: 10.1152/jn.1997.78.5.2790.Peer-Reviewed Original ResearchConceptsDorsal root gangliaUnmyelinated axonsRoot gangliaSodium currentTTX-sensitive sodium currentWhole-cell patch-clamp recordingsCell patch-clamp recordingsDorsal root ganglion cellsTTX-resistant currentC cellsEffects of axotomyAction potential thresholdPatch-clamp recordingsAction potential durationNeuropathic painVoltage-clamp conditionsPeak sodium currentDRG cellsGanglion cellsSoma sizeFast BlueNerve fibersConduction velocityAxotomyPotential duration
1991
Multidrug resistance in human neuroblastoma cells
LaQuaglia M, Kopp E, Spengler B, Meyers M, Biedler J. Multidrug resistance in human neuroblastoma cells. Journal Of Pediatric Surgery 1991, 26: 1107-1112. PMID: 1719182, DOI: 10.1016/0022-3468(91)90684-l.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic AgentsATP Binding Cassette Transporter, Subfamily B, Member 1Cell LineColchicineDactinomycinDNA, NeoplasmDoxorubicinDrug ResistanceGene AmplificationHumansImmunoblottingMembrane GlycoproteinsNeoplasm ProteinsNeuroblastomaProto-Oncogene Proteins c-mycRNA, NeoplasmTumor Cells, CulturedVincristineConceptsHuman neuroblastoma cellsMultidrug-resistant phenotypeChemotherapeutic agentsNeuroblastoma cellsMultidrug resistanceProtein levelsN-myc amplificationHuman neuroblastoma SKDrug-resistant sublinesSteady-state messenger RNAConcentration of actinomycinPediatric oncologyN-myc protooncogeneP-glycoproteinNeuroblastoma SKWestern blottingRNA levelsC cellsDot blot analysisPossible alterationsGene amplificationSublinesMessenger RNANatural product drugsStepwise increase
1990
Search for the Gene for Multiple Endocrine Neoplasia Type 2A
KIDD K, SIMPSON N. Search for the Gene for Multiple Endocrine Neoplasia Type 2A. 1990, 46: 305-343. PMID: 2281187, DOI: 10.1016/b978-0-12-571146-3.50015-8.Peer-Reviewed Original ResearchConceptsMultiple endocrine neoplasia type 2AType 2AElevated hormone levelsHereditary cancer syndromesMultiple endocrine glandsSlow growingAbnormal alleleMedullary carcinomaAssociated mortalityParathyroid glandsHormone levelsUnique tissue distributionSerious symptomsTissue massCancer syndromesEndocrine glandsVital organsClinical useRisk estimatesTumorsTissue distributionC cellsElevated productionAdditional markersThyroid
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