1993
Human neuroblastoma cell lines that express N‐myc without gene amplification
Wada R, Seeger R, Brodeur G, Einhorn P, Rayner S, Tomayko M, Reynolds C. Human neuroblastoma cell lines that express N‐myc without gene amplification. Cancer 1993, 72: 3346-3354. PMID: 8242562, DOI: 10.1002/1097-0142(19931201)72:11<3346::aid-cncr2820721134>3.0.co;2-e.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, NeoplasmAntigens, SurfaceBiomarkers, TumorCatecholaminesCell DivisionChild, PreschoolGene AmplificationGene Expression Regulation, NeoplasticGenes, mycHumansKaryotypingMaleNeuritesNeuroblastomaProto-Oncogene Proteins c-mycTime FactorsTranscriptional ActivationTumor Cells, CulturedConceptsGenomic amplificationN-myc expressionCell linesN-mycNeuroblastoma cell linesUnique genetic rearrangementDouble minute chromosomesGene activationChromosome 2New cell lineGenetic rearrangementsChromosomal deletionsHuman neuroblastoma cell lineBone marrow metastasesStage IV neuroblastomaCell surface antigen expressionN-myc amplificationAggressive tumor behaviorGene amplificationSurface antigen expressionCytogenetic analysisN-myc RNAProgressive diseaseBiological basisMarrow metastases
1991
Multidrug resistance in human neuroblastoma cells
LaQuaglia M, Kopp E, Spengler B, Meyers M, Biedler J. Multidrug resistance in human neuroblastoma cells. Journal Of Pediatric Surgery 1991, 26: 1107-1112. PMID: 1719182, DOI: 10.1016/0022-3468(91)90684-l.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic AgentsATP Binding Cassette Transporter, Subfamily B, Member 1Cell LineColchicineDactinomycinDNA, NeoplasmDoxorubicinDrug ResistanceGene AmplificationHumansImmunoblottingMembrane GlycoproteinsNeoplasm ProteinsNeuroblastomaProto-Oncogene Proteins c-mycRNA, NeoplasmTumor Cells, CulturedVincristineConceptsHuman neuroblastoma cellsMultidrug-resistant phenotypeChemotherapeutic agentsNeuroblastoma cellsMultidrug resistanceProtein levelsN-myc amplificationHuman neuroblastoma SKDrug-resistant sublinesSteady-state messenger RNAConcentration of actinomycinPediatric oncologyN-myc protooncogeneP-glycoproteinNeuroblastoma SKWestern blottingRNA levelsC cellsDot blot analysisPossible alterationsGene amplificationSublinesMessenger RNANatural product drugsStepwise increase
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