Multidrug resistance in human neuroblastoma cells
LaQuaglia M, Kopp E, Spengler B, Meyers M, Biedler J. Multidrug resistance in human neuroblastoma cells. Journal Of Pediatric Surgery 1991, 26: 1107-1112. PMID: 1719182, DOI: 10.1016/0022-3468(91)90684-l.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic AgentsATP Binding Cassette Transporter, Subfamily B, Member 1Cell LineColchicineDactinomycinDNA, NeoplasmDoxorubicinDrug ResistanceGene AmplificationHumansImmunoblottingMembrane GlycoproteinsNeoplasm ProteinsNeuroblastomaProto-Oncogene Proteins c-mycRNA, NeoplasmTumor Cells, CulturedVincristineConceptsHuman neuroblastoma cellsMultidrug-resistant phenotypeChemotherapeutic agentsNeuroblastoma cellsMultidrug resistanceProtein levelsN-myc amplificationHuman neuroblastoma SKDrug-resistant sublinesSteady-state messenger RNAConcentration of actinomycinPediatric oncologyN-myc protooncogeneP-glycoproteinNeuroblastoma SKWestern blottingRNA levelsC cellsDot blot analysisPossible alterationsGene amplificationSublinesMessenger RNANatural product drugsStepwise increase
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