2023
Alcohol-mediated renal denervation in patients with hypertension in the absence of antihypertensive medications.
Pathak A, Rudolph U, Saxena M, Zeller T, Müller-Ehmsen J, Lipsic E, Schmieder R, Sievert H, Halbach M, Sharif F, Parise H, Fischell T, Weber M, Kandzari D, Mahfoud F. Alcohol-mediated renal denervation in patients with hypertension in the absence of antihypertensive medications. EuroIntervention 2023, 19: 602-611. PMID: 37427416, PMCID: PMC10493775, DOI: 10.4244/eij-d-23-00088.Peer-Reviewed Original ResearchConceptsSystolic blood pressureRenal denervationBlood pressureAntihypertensive medicationsRDN groupMedication burdenMean office blood pressureOffice systolic blood pressureSystolic BP 140Office blood pressurePrimary efficacy endpointMajor adverse eventsSystolic BP changeDiastolic blood pressureLower blood pressureRadiofrequency renal denervationLower medication burdenSignificant BP differencesMedication escalationEfficacy endpointSafety endpointAdverse eventsSham groupBP changesMedication washoutTrajectory of blood pressure after initiating anti-calcitonin gene-related peptide treatment of migraine: a target trial emulation from the veterans health administration
Wang K, Fenton B, Dao V, Guirguis A, Anthony S, Skanderson M, Sico J. Trajectory of blood pressure after initiating anti-calcitonin gene-related peptide treatment of migraine: a target trial emulation from the veterans health administration. The Journal Of Headache And Pain 2023, 24: 108. PMID: 37582724, PMCID: PMC10426172, DOI: 10.1186/s10194-023-01640-y.Peer-Reviewed Original ResearchConceptsAnti-CGRP treatmentVeterans Health AdministrationBlood pressureBP changesHealth AdministrationDiastolic BP changesExacerbation of hypertensionNumber of antihypertensivesIncidence of hypertensionHigher healthcare utilizationSystolic BP changeKaplan-Meier curvesBlood pressure readingsGene-related peptideTarget trial emulationYears of treatmentBlood pressure regulationHigh-quality real-world evidenceReal-world evidenceMixed-effects Poisson modelsChronic migraine diagnosisInverse probability weightsAntihypertension medicationsAntihypertensive medicationsBaseline hypertensionAssociations of SGLT2 genetic polymorphisms with salt sensitivity, blood pressure changes and hypertension incidence in Chinese adults
Jia H, Bao P, Yao S, Zhang X, Mu J, Hu G, Du M, Chu C, Zhang X, Wang L, Liao Y, Wang D, Ma Q, Yan Y, Niu Z, Gao W, Li H, Wu G, Chang J, Wang Y. Associations of SGLT2 genetic polymorphisms with salt sensitivity, blood pressure changes and hypertension incidence in Chinese adults. Hypertension Research 2023, 46: 1795-1803. PMID: 37160967, DOI: 10.1038/s41440-023-01301-2.Peer-Reviewed Original ResearchConceptsLongitudinal BP changesLow-salt dietDevelopment of hypertensionBlood pressureHypertension incidenceBP changesSodium-glucose cotransporter 2 inhibitorsSalt sensitivityCotransporter 2 inhibitorsIncidence of hypertensionHigh-salt dietSystolic blood pressureBlood pressure changesGenetic polymorphismsIncident hypertensionSystolic BPDietary interventionSBP changeUsual dietHypertensionChinese adultsSalutary effectsIncidenceDietSGLT2
2022
Blood pressure response to commonly administered antihypertensives for severe inpatient hypertension
Ghazi L, Li F, Chen X, Simonov M, Yamamoto Y, Biswas A, Hanna J, Shah T, Peixoto AJ, Wilson FP. Blood pressure response to commonly administered antihypertensives for severe inpatient hypertension. PLOS ONE 2022, 17: e0265497. PMID: 35385506, PMCID: PMC8985959, DOI: 10.1371/journal.pone.0265497.Peer-Reviewed Original ResearchConceptsHTN developmentSevere hypertensionOral hydralazineOral carvedilolIntensive care unit patientsBlood pressure elevationCare unit patientsAssociation of treatmentSingle healthcare systemAntihypertensive treatmentCommon antihypertensivesInpatient hypertensionOral amlodipinePrescribed antihypertensivesOral metoprololClinical characteristicsCohort studyUnit patientsBP responseHospitalized patientsPressure elevationBP changesLower BPHypertensionHydralazine
2013
Reproducibility of ambulatory blood pressure changes from the initial values on two different days
Ash GI, Walker TJ, Olson KM, Stratton JH, Gómez AL, Kraemer WJ, Volek JS, Pescatello LS. Reproducibility of ambulatory blood pressure changes from the initial values on two different days. Clinics 2013, 68: 1509-1515. PMID: 24473508, PMCID: PMC3840371, DOI: 10.6061/clinics/2013(12)06.Peer-Reviewed Original ResearchConceptsAmbulatory BP changesAmbulatory BP monitorBP changesBlood pressureDay 1Day 2BP monitorAmbulatory blood pressure changesDiastolic BP changesNormal blood pressureAmbulatory blood pressureBlood pressure changesCardiovascular health outcomesAlerting reactionReproducibility of changesDifferent daysBP reactivityHealth outcomesHealthy adultsSame investigatorNext morningWomenMeasures analysisMenTotal sample
2007
Exceptional early blood pressure control rates: The ACCOMPLISH trial
Jamerson K, Bakris GL, Dahlöf B, Pitt B, Velazquez E, Gupte J, Lefkowitz M, Hester A, Shi V, Kjeldsen SE, Cushman W, Papademetriou V, Weber M, Jamerson K, Bakris G, Dahlöf B, Pitt B, Velazquez E, Gupte J, Lefkowitz M, Hester A, Shi V, Kjeldsen S, Cushman W, Papademetriou V, Weber M. Exceptional early blood pressure control rates: The ACCOMPLISH trial. Blood Pressure 2007, 16: 80-86. PMID: 17612905, DOI: 10.1080/08037050701395571.Peer-Reviewed Original ResearchConceptsBP control ratesControl rateCombination therapyHigh-risk hypertensionMean BP changeMulti-national trialStage 2 hypertensionAnti-hypertensive medicationsBlood pressure controlACCOMPLISH trialMaximal medicationHypertension trialsMean BPRenal diseaseInitial treatmentBP changesHypotensive eventsCurrent guidelinesPressure controlHypertensionOverall trialPatientsTherapyTrialsAnalysis of variance
1984
PROSTAGLANDIN-MEDIATED CONTROL OF NEONATAL CEREBRAL BLOOD FLOW
Ment L, Stewart W, Duncan C, Pitt B. PROSTAGLANDIN-MEDIATED CONTROL OF NEONATAL CEREBRAL BLOOD FLOW. Pediatric Research 1984, 18: 380-380. DOI: 10.1203/00006450-198404001-01722.Peer-Reviewed Original ResearchCerebral blood flowNeonatal cerebral blood flowIntraventricular hemorrhageNewborn beagle pupsBP changesCBF changesBeagle pupsBlood flowSuperoxide dismutaseBaseline cerebral blood flowNeonatal intraventricular hemorrhageCyclo-oxygenase pathwaySynthesis of TxB2Free radical scavengerPreterm neonatesHemorrhagic hypotensionCapillary changesIndomethacinPupsSynthetic enzymesAlterationsBreakdown productsHypotensionHemorrhageNeonates
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