2023
Alcohol withdrawal syndrome in trauma patients: a study using the Trauma Quality Program Participant User File
Jones T, Bhattacharya B, Schuster K, Becher R, Kodadek L, Davis K, Maung A. Alcohol withdrawal syndrome in trauma patients: a study using the Trauma Quality Program Participant User File. Trauma Surgery & Acute Care Open 2023, 8: e001047. PMID: 37188153, PMCID: PMC10175962, DOI: 10.1136/tsaco-2022-001047.Peer-Reviewed Original ResearchAlcohol withdrawal syndromeAlcohol use disorderPositive blood alcohol concentrationHistory of AUDBlood alcohol concentrationParticipant User FileAdult patientsTrauma patientsWithdrawal syndromeAbbreviated Injury Scale headHigh-risk patient populationInjury scale headAdult trauma patientsPositive toxicology screenMultivariable logistic regressionRetrospective reviewRetrospective studyToxicology screenPatient populationTricyclic antidepressantsMAIN OUTCOMEAmerican CollegePatientsUse disordersUncommon occurrence
2020
A feasibility study providing substance use treatment in the Black church
Jordan A, Babuscio T, Nich C, Carroll KM. A feasibility study providing substance use treatment in the Black church. Journal Of Substance Use And Addiction Treatment 2020, 124: 108218. PMID: 33771290, DOI: 10.1016/j.jsat.2020.108218.Peer-Reviewed Original ResearchConceptsTechnology-based treatmentsClinical trialsSUD treatmentBlack adultsNonrandomized feasibility studyUrine toxicology screenHealth care disparitiesEvidence-based interventionsDSM-5 criteriaAdequate numberCognitive behavioral therapyDisseminable strategyUndertreated populationToxicology screenCurrent SUDCare disparitiesHealth advisorsBehavioral therapySubstance useMean numberTreatmentHigh uptakeFeasibility studyCBT4CBTTrials
2019
The Relevance of Sex in the Association of Synthetic Cannabinoid Use With Psychosis and Agitation in an Inpatient Population.
Bassir Nia A, Mann CL, Spriggs S, DeFrancisco DR, Carbonaro S, Parvez L, Galynker II, Perkel CA, Hurd YL. The Relevance of Sex in the Association of Synthetic Cannabinoid Use With Psychosis and Agitation in an Inpatient Population. The Journal Of Clinical Psychiatry 2019, 80 PMID: 31265768, PMCID: PMC8445109, DOI: 10.4088/jcp.18m12539.Peer-Reviewed Original ResearchConceptsToxicology screenRelevance of sexSynthetic cannabinoid useSC usePositive urine toxicology screenCannabinoid useUrine toxicology screenRetrospective chart reviewPositive toxicology screenEffects of cannabinoidsSC usersRates of psychosisChart reviewPharmacologic treatmentClinical symptomsInpatient populationInpatient settingPsychotic presentationsUse of substancesStudy groupHigh riskPsychiatric unitCurrent evidenceControl groupPsychosisDifferential outcomes following successful resuscitation in cardiac arrest due to drug overdose
Ormseth CH, Maciel CB, Zhou SE, Barden MM, Miyares LC, Beekman RB, Gilmore EJ, Greer DM. Differential outcomes following successful resuscitation in cardiac arrest due to drug overdose. Resuscitation 2019, 139: 9-16. PMID: 30965094, DOI: 10.1016/j.resuscitation.2019.04.004.Peer-Reviewed Original ResearchConceptsCardiac arrestNeurological recoveryClinical characteristicsDrug overdoseBrain deathCerebral Performance Category scoreCA casesFavorable neurological recoverySimilar neurological recoveryLarge prospective studiesPositive toxicology screenRankin Scale scorePotential treatment optionSingle academic institutionBystander cardiopulmonary resuscitationHospital dischargeInpatient mortalitySuccessful resuscitationToxicology screenProspective studyTreatment optionsMedical recordsMedication administrationCardiopulmonary resuscitationRetrospective analysisRandomized Pilot Trial of Web-Based Cognitive-Behavioral Therapy Adapted for use in Office-Based Buprenorphine Maintenance
Shi JM, Henry SP, Dwy SL, Orazietti SA, Carroll KM. Randomized Pilot Trial of Web-Based Cognitive-Behavioral Therapy Adapted for use in Office-Based Buprenorphine Maintenance. Substance Abuse 2019, 40: 132-135. PMID: 30714880, PMCID: PMC6874094, DOI: 10.1080/08897077.2019.1569192.Peer-Reviewed Original ResearchConceptsOffice-based buprenorphineOpioid use disorderBuprenorphine treatmentWeb-based interventionBuprenorphine maintenancePilot trialUse disordersBehavioral careCurrent opioid use disorderOffice-based buprenorphine treatmentUrine toxicology screenSpecific patient populationsDays of treatmentDSM-5 criteriaCognitive behavioral therapyInitial pilot testingToxicology screenPatient populationTwelve-weekEffective treatmentBuprenorphineDrug useSmall sample sizeTrialsPromising findings
2018
Galantamine and Computerized Cognitive Behavioral Therapy for Cocaine Dependence: A Randomized Clinical Trial.
Carroll KM, Nich C, DeVito EE, Shi JM, Sofuoglu M. Galantamine and Computerized Cognitive Behavioral Therapy for Cocaine Dependence: A Randomized Clinical Trial. The Journal Of Clinical Psychiatry 2018, 79: 17m11669. PMID: 29286595, PMCID: PMC5866530, DOI: 10.4088/jcp.17m11669.Peer-Reviewed Original ResearchConceptsComputerized cognitive behavioral therapyStandard methadone treatmentCocaine use outcomesBenefits of galantamineMethadone treatmentCognitive behavioral therapyCognitive functionUse outcomesCommunity-based methadone maintenance programCocaine useStandard methadone maintenance treatmentBehavioral therapyUrine toxicology screenMethadone maintenance treatmentMethadone maintenance programCocaine treatment outcomesNicotinic acetylcholine receptorsCognitive functioningCocaine use disorderMethadone dosingSecondary outcomesToxicology screenMaintenance treatmentClinical trialsMedication administration
2017
Diagnostic Tests for Evaluation of Stillbirth
Page JM, Christiansen-Lindquist L, Thorsten V, Parker CB, Reddy UM, Dudley DJ, Saade GR, Coustan D, Hogue C, Conway D, Bukowski R, Pinar H, Heuser CC, Gibbins KJ, Goldenberg RL, Silver RM. Diagnostic Tests for Evaluation of Stillbirth. Obstetrics And Gynecology 2017, 129: 699-706. PMID: 28333795, DOI: 10.1097/aog.0000000000001937.Peer-Reviewed Original ResearchConceptsStillbirth Collaborative Research NetworkCause of deathAntiphospholipid antibodiesPlacental pathologyDiagnostic testsEvaluation of stillbirthMedical record abstractionPopulation-based studyCollaborative research networksDeath classification systemResearch NetworkRecord abstractionSyphilis serologyClinical presentationToxicology screenAntibody screenClinical historyMaternal interviewsStillbirthSecondary analysisGenetic testingUseful testBiospecimen collectionStandardized evaluationMost participants
2016
Just Showing Up Is Not Enough: Homework Adherence and Outcome in Cognitive–Behavioral Therapy for Cocaine Dependence
Decker SE, Kiluk BD, Frankforter T, Babuscio T, Nich C, Carroll KM. Just Showing Up Is Not Enough: Homework Adherence and Outcome in Cognitive–Behavioral Therapy for Cocaine Dependence. Journal Of Consulting And Clinical Psychology 2016, 84: 907-912. PMID: 27454780, PMCID: PMC5341374, DOI: 10.1037/ccp0000126.Peer-Reviewed Original ResearchConceptsUrine toxicology screenCognitive behavioral therapyCocaine use outcomesHomework adherenceTreatment attendanceToxicology screenCocaine useUse outcomesMultiple logistic regressionBaseline cocaine useVariety of disordersCocaine use severityTreatment endClinical trialsCocaine use frequencyImproved outcomesCocaine dependenceLogistic regressionCBT sessionsAdherenceUse severityPrior studiesGreater reductionOutcomesTreatmentModafinil and sleep architecture in an inpatient–outpatient treatment study of cocaine dependence
Morgan PT, Angarita GA, Canavan S, Pittman B, Oberleitner L, Malison RT, Mohsenin V, Hodges S, Easton C, McKee S, Bessette A, Forselius E. Modafinil and sleep architecture in an inpatient–outpatient treatment study of cocaine dependence. Drug And Alcohol Dependence 2016, 160: 49-56. PMID: 26777774, PMCID: PMC4767553, DOI: 10.1016/j.drugalcdep.2015.12.004.Peer-Reviewed Original ResearchConceptsUrine toxicology screenModafinil treatmentSlow-wave sleepClinical outcomesOutpatient treatmentToxicology screenUrine screensInpatient settingInpatient treatmentSleep timeCocaine dependencePrimary clinical outcomeWeekly cognitive behavioral therapyCocaine usersImproved clinical outcomesPolysomnographic sleep recordingsChronic cocaine useChronic cocaine usersHigh rateCognitive behavioral therapyCocaine-dependent participantsSleep architectureOutpatient phaseEffective treatmentDays abstinent
2015
Outcome expectations and associated treatment outcomes in motivational enhancement therapy delivered in English and Spanish
Serafini K, Decker S, Kiluk BD, Añez L, Paris M, Frankforter T, Carroll KM. Outcome expectations and associated treatment outcomes in motivational enhancement therapy delivered in English and Spanish. American Journal On Addictions 2015, 24: 732-739. PMID: 26541501, PMCID: PMC4885684, DOI: 10.1111/ajad.12301.Peer-Reviewed Original ResearchConceptsPatients' outcome expectationsTreatment outcomesMotivational enhancement therapyEnhancement therapyUrine toxicology screenLikelihood of abstinenceSubstance use disordersSubstance use outcomesToxicology screenClinical trialsTreatment periodUse disordersOutcome expectationsSecondary analysisSubstance useAbstinenceUse outcomesOutcomesMetSTherapyTreatmentBaseline expectationsGreater percentageSame treatmentImportant predictor
2014
Profiles of psychiatric symptoms among amphetamine type stimulant and ketamine using inpatients in Wuhan, China
Zhang Y, Xu Z, Zhang S, Desrosiers A, Schottenfeld RS, Chawarski MC. Profiles of psychiatric symptoms among amphetamine type stimulant and ketamine using inpatients in Wuhan, China. Journal Of Psychiatric Research 2014, 53: 99-102. PMID: 24613031, PMCID: PMC4004368, DOI: 10.1016/j.jpsychires.2014.02.010.Peer-Reviewed Original ResearchConceptsBrief Psychiatric Rating ScalePsychiatric symptomsAmphetamine-type stimulantsKetamine groupKetamine useAnxiety depressionInpatient psychiatry wardUrine toxicology screenProportion of participantsPsychiatric Rating ScaleLower scoresWard admissionToxicology screenClinical recordsPsychiatry wardInpatient treatmentHigher scoresPrimary drugATS useBPRS subscalesMajor drug problemStudy participantsKetamineSymptomsATS users
2013
Differential diagnosis for a stable patient maintained on buprenorphine who gives a urine toxicology screen negative for buprenorphine
Sethi R, Petrakis I. Differential diagnosis for a stable patient maintained on buprenorphine who gives a urine toxicology screen negative for buprenorphine. American Journal On Addictions 2013 DOI: 10.1111/j.1521-0391.2013.12087.x.Peer-Reviewed Original Research
2012
Use of haloperidol in PCP-intoxicated individuals
Macneal JJ, Cone DC, Sinha V, Tomassoni AJ. Use of haloperidol in PCP-intoxicated individuals. Journal Of Toxicology Clinical Toxicology 2012, 50: 851-853. PMID: 22970762, DOI: 10.3109/15563650.2012.722222.Peer-Reviewed Original ResearchConceptsChemical restraintAdverse eventsPCP-positive patientsUse of haloperidolRetrospective case seriesTertiary care hospitalFurther prospective studiesElectronic medical recordsEmergency medical workersChart reviewAdult patientsCase seriesPatient dispositionProspective studyToxicology screenIntoxicated patientsMedical recordsIdentified casesHaloperidolPatientsMedical workersPCPSedationHospitalDoses
2004
Efficacy of Disulfiram and Cognitive Behavior Therapy in Cocaine-DependentOutpatients: A Randomized Placebo-Controlled Trial
Carroll KM, Fenton LR, Ball SA, Nich C, Frankforter TL, Shi J, Rounsaville BJ. Efficacy of Disulfiram and Cognitive Behavior Therapy in Cocaine-DependentOutpatients: A Randomized Placebo-Controlled Trial. JAMA Psychiatry 2004, 61: 264-272. PMID: 14993114, PMCID: PMC3675448, DOI: 10.1001/archpsyc.61.3.264.Peer-Reviewed Original ResearchConceptsCocaine useGeneral populationCocaine dependenceEfficacy of disulfiramUrine toxicology screenOutpatient substance abuse treatment programsBehavior therapyConcurrent alcohol useSubstance abuse treatment programsCurrent cocaine dependenceCognitive behavior therapyDisulfiram useRandomized PlaceboDisulfiram therapyMedication complianceToxicology screenIdentical capsulesEffective therapyPlaceboCocaine-dependent individualsSelf-reported frequencyPromising treatmentPlacebo conditionInterpersonal psychotherapyTherapy
2001
Buprenorphine for opiate addiction: potential economic impact
Rosenheck R, Kosten T. Buprenorphine for opiate addiction: potential economic impact. Drug And Alcohol Dependence 2001, 63: 253-262. PMID: 11418229, DOI: 10.1016/s0376-8716(00)00214-3.Peer-Reviewed Original ResearchConceptsBuprenorphine/naloxoneBuprenorphine/naloxone therapyBuprenorphine/naloxone combinationOffice-based treatmentHigh-cost patientsNet cost savingsNaloxone therapyToxicology screenMethadone clinicsNaloxone combinationNursing costsTreatment opportunitiesMultiple detoxificationsOpiate addictionNaloxoneOffice practicePatientsComparable groupsAdverse effectsMethadoneTreatmentAddictsNet savingsAddiction
2000
One‐year follow‐up of disulfiram and psychotherapy for cocaine‐alcohol users: sustained effects of treatment
Carroll K, Nich C, Ball S, McCance E, Frankforter T, Rounsaville B. One‐year follow‐up of disulfiram and psychotherapy for cocaine‐alcohol users: sustained effects of treatment. Addiction 2000, 95: 1335-1349. PMID: 11048353, DOI: 10.1046/j.1360-0443.2000.95913355.x.Peer-Reviewed Original ResearchConceptsCognitive-behavioral treatmentTwelve-step facilitationInitiation of abstinenceAlcohol useSubstance abuse treatment centersFrequency of cocaineAlcohol-dependent individualsClinical managementMain effectBrief treatmentEfficacy of disulfiramUrine toxicology screenCessation of treatmentBreathalyzer testEnd of treatmentOutcomes 1 yearAbstinencePercentage of daysEffect of treatmentCocaineLong-term benefitsToxicology screenTreatment centersBetter outcomesBrief periodA Randomized Controlled Trial of Auricular Acupuncture for Cocaine Dependence
Avants S, Margolin A, Holford T, Kosten T. A Randomized Controlled Trial of Auricular Acupuncture for Cocaine Dependence. JAMA Internal Medicine 2000, 160: 2305-2312. PMID: 10927727, DOI: 10.1001/archinte.160.15.2305.Peer-Reviewed Original ResearchConceptsAuricular acupunctureCocaine dependenceCocaine addictionOpiate dependent populationUrine toxicology screenMethadone-maintained patientsCocaine-negative urine samplesDrug treatment facilitiesPrimary outcomeControlled TrialsToxicology screenTreatment modalitiesTreat sampleEffective treatmentUrine dataAcupunctureTreatment sessionsCocaine useRelaxation controlUrine samplesPatientsLongitudinal analysisTreatmentFurther investigationControl conditionA Path Analysis of Cognitive, Affective, and Behavioral Predictors of Treatment Response in a Methadone Maintenance Program
Avants S, Margolin A, McKee S. A Path Analysis of Cognitive, Affective, and Behavioral Predictors of Treatment Response in a Methadone Maintenance Program. Journal Of Substance Abuse 2000, 11: 215-230. PMID: 11026121, DOI: 10.1016/s0899-3289(00)00022-5.Peer-Reviewed Original ResearchConceptsMethadone maintenance programMethadone maintenance treatmentMaintenance treatmentPre-treatment severityTreatment responseStructural equation modelingCocaine useUrine toxicology screenOpioid-dependent patientsOpioid-dependent individualsPsychosocial group interventionBehavioral predictorsIllicit drug useToxicology screenHeroin useIntake assessmentDrug useIllicit opiatesGroup interventionNegative affectSelf-schemaAbstinenceStrongest predictorMethadoneEquation modelingDisulfiram treatment for cocaine dependence in methadone‐maintained opioid addicts
Petrakis IL, Carroll KM, Nich C, Gordon LT, McCance-Katz EF, Frankforter T, Rounsaville BJ. Disulfiram treatment for cocaine dependence in methadone‐maintained opioid addicts. Addiction 2000, 95: 219-228. PMID: 10723850, DOI: 10.1046/j.1360-0443.2000.9522198.x.Peer-Reviewed Original ResearchConceptsCo-morbid alcohol abuseOpioid addictsAlcohol abuseCocaine abuseCocaine dependenceAlcohol useEfficacy of disulfiramExcess of dopamineUrine toxicology screenPlacebo-controlled trialPrimary outcome measureMethadone maintenance treatmentOpioid-dependent subjectsRe-uptake inhibitorsMethadone maintenance clinicsSynthesis of norepinephrineFrequency of cocaineStudy medicationToxicology screenComorbid alcoholMaintenance treatmentPoor prognosisEffective pharmacotherapyDisulfiram treatmentMaintenance clinics
1997
Effectiveness of treatment elements in a residential-work therapy program for veterans with severe substance abuse
Rosenheck R, Seibyl C. Effectiveness of treatment elements in a residential-work therapy program for veterans with severe substance abuse. Psychiatric Services 1997, 48: 928-935. PMID: 9219302, DOI: 10.1176/ps.48.7.928.Peer-Reviewed Original ResearchMeSH KeywordsAdultChi-Square DistributionChronic DiseaseDiagnosis, Dual (Psychiatry)FemaleHumansJob SatisfactionLength of StayLongitudinal StudiesMaleOutcome and Process Assessment, Health CareProgram EvaluationRegression AnalysisSeverity of Illness IndexSheltered WorkshopsSocial AdjustmentSubstance-Related DisordersTreatment OutcomeUnited StatesVeteransConceptsSevere substance abuseSubstance abuseTreatment elementsTherapy programSevere substance use disordersAdmission risk factorsBaseline prognostic factorsLength of staySubstance use disordersPrognostic factorsToxicology screenFunctional statusRisk factorsIntensive treatmentOutcome measuresOutcome dataUse disordersRehabilitative approachVeterans AffairsOutcome domainsSignificant relationshipSubstance useOutcomesVeteransTreatment
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