2025
Microglia positron emission tomography and progression in multiple sclerosis: thalamus on fire
Zeydan B, Neyal N, Son J, Schwarz C, Thomas J, Morrison H, Bush M, Reid R, Przybelski S, Fought A, Jack C, Petersen R, Kantarci K, Lowe V, Airas L, Kantarci O. Microglia positron emission tomography and progression in multiple sclerosis: thalamus on fire. Brain Communications 2025, 7: fcaf141. PMID: 40322777, PMCID: PMC12046125, DOI: 10.1093/braincomms/fcaf141.Peer-Reviewed Original ResearchProgressive multiple sclerosisRelapsing Multiple SclerosisPET uptakeMultiple sclerosisThalamic lesionsMicroglia densityMean diffusivityPaced Auditory Serial Addition Test scoresMultiple Sclerosis Functional Composite scoreClinical disease severityNeurite density indexBiomarkers of progressionAssociated with imaging biomarkersPositron emission tomographyGlobal disease burdenTranslocator protein PETOrientation dispersion indexDisease characteristicsPatientsEfficacy evaluationImaging biomarkersCorpus callosumEmission tomographyDisease severityThalamus
2020
Robot-assisted stereotactic biopsy of pediatric brainstem and thalamic lesions.
Gupta M, Chan TM, Santiago-Dieppa DR, Yekula A, Sanchez CE, Elster JD, Crawford JR, Levy ML, Gonda DD. Robot-assisted stereotactic biopsy of pediatric brainstem and thalamic lesions. Journal Of Neurosurgery Pediatrics 2020, 27: 317-324. PMID: 33361479, DOI: 10.3171/2020.7.peds20373.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBiopsyBrain NeoplasmsBrain StemBrain Stem NeoplasmsChildChild, PreschoolFemaleGliomaHematomaHumansImaging, Three-DimensionalMalePatient PositioningPredictive Value of TestsRetrospective StudiesRobotic Surgical ProceduresStereotaxic TechniquesThalamic DiseasesThalamusYoung AdultConceptsRobot-assisted biopsiesStereotactic biopsyPediatric brainstemThalamic lesionsLesional tissueMajor adverse outcomesLarge clinical seriesRady Children's HospitalBiopsy of tumorsDiagnostic success rateDeep midline structuresAsymptomatic hematomaCranial neuropathiesConsecutive patientsThalamic tumorsAdverse outcomesChildren's HospitalClinical seriesDiencephalic tumorsPermanent deficitsSurgeon preferenceInstitutional experienceRetrospective analysisBiopsyBrainstem
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