Microglia positron emission tomography and progression in multiple sclerosis: thalamus on fire
Zeydan B, Neyal N, Son J, Schwarz C, Thomas J, Morrison H, Bush M, Reid R, Przybelski S, Fought A, Jack C, Petersen R, Kantarci K, Lowe V, Airas L, Kantarci O. Microglia positron emission tomography and progression in multiple sclerosis: thalamus on fire. Brain Communications 2025, 7: fcaf141. PMID: 40322777, PMCID: PMC12046125, DOI: 10.1093/braincomms/fcaf141.Peer-Reviewed Original ResearchProgressive multiple sclerosisRelapsing Multiple SclerosisPET uptakeMultiple sclerosisThalamic lesionsMicroglia densityMean diffusivityPaced Auditory Serial Addition Test scoresMultiple Sclerosis Functional Composite scoreClinical disease severityNeurite density indexBiomarkers of progressionAssociated with imaging biomarkersPositron emission tomographyGlobal disease burdenTranslocator protein PETOrientation dispersion indexDisease characteristicsPatientsEfficacy evaluationImaging biomarkersCorpus callosumEmission tomographyDisease severityThalamus
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