2025
Impact of pregnancy history and recency of childbirth on long-term outcomes in young patients with early-stage breast cancer.
Nader Marta G, Zheng Y, Rosenberg S, Dibble K, Mayer E, Poorvu P, Ruddy K, Guzman Arocho Y, Collins L, Peppercorn J, Schapira L, Borges V, Tayob N, Come S, Warner E, Polyak K, Winer E, Partridge A. Impact of pregnancy history and recency of childbirth on long-term outcomes in young patients with early-stage breast cancer. Journal Of Clinical Oncology 2025, 43: e12562-e12562. DOI: 10.1200/jco.2025.43.16_suppl.e12562.Peer-Reviewed Original ResearchYoung Women's Breast Cancer StudyPregnancy historyLong-term outcomesBreast cancerBC subtypesYounger patientsAssociated with worse DRFSManagement of breast cancerPregnancy-related hormonal changesEarly-stage breast cancerLong-term disease outcomesBreast Cancer StudyRecurrence-free survivalMedian Follow-UpEarly breast cancerEarly-stage BCAggressive clinical featuresTime of diagnosisWomen many yearsN1 statusYounger ptsT3 tumorsNodal statusT1 tumorsN0 status
2023
Malignant Melanoma in Older Adults: Different Patient or Different Disease?
Sasson D, Smetona J, Parsaei Y, Papageorge M, Ariyan S, Olino K, Clune J. Malignant Melanoma in Older Adults: Different Patient or Different Disease? Cureus 2023, 15: e34742. PMID: 36909026, PMCID: PMC9998075, DOI: 10.7759/cureus.34742.Peer-Reviewed Original ResearchMelanoma-specific survivalRecurrence-free survivalOlder patientsT2 tumorsNodal positivityMetastatic progressionOlder adultsConclusion Older adultsLog-rank testingKaplan-Meier analysisT4 tumorsYounger patientsT1 tumorsBreslow thicknessClinical outcomesTumor characteristicsTumor thicknessSingle institutionClinical behaviorMalignant melanomaLower incidenceHigh incidencePatientsConsecutive sampleAge groups
2017
Indications for invasive mediastinal staging in patients with early non-small cell lung cancer staged with PET-CT
Gao SJ, Kim AW, Puchalski JT, Bramley K, Detterbeck FC, Boffa DJ, Decker RH. Indications for invasive mediastinal staging in patients with early non-small cell lung cancer staged with PET-CT. Lung Cancer 2017, 109: 36-41. PMID: 28577947, DOI: 10.1016/j.lungcan.2017.04.018.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCarcinoma, Non-Small-Cell LungClinical Decision-MakingDiagnostic ImagingFemaleHumansLung NeoplasmsMaleMediastinumMiddle AgedNeoplasm MetastasisNeoplasm StagingPatient SelectionPositron Emission Tomography Computed TomographyPractice Guidelines as TopicRetrospective StudiesConceptsOccult N2 diseaseOccult N2 metastasesGround-glass componentInvasive mediastinal stagingCurative-intent therapyT2 tumorsN2 metastasisPET-CTInvasive stagingN2 diseaseT1 tumorsNegative predictive valueMediastinal stagingEarly non-small cell lung cancerExact testPredictive valueSolid tumorsNon-small cell lung cancerClinical stage I NSCLCN2 lymph nodesNode-negative NSCLCOccult nodal involvementPure-solid tumorsStage I NSCLCT1-2N0 disease
2012
The Prognostic Importance of Midline Involvement in Oral Tongue Cancer
Lloyd S, Yu JB, Wilson LD, Judson BL, Decker RH. The Prognostic Importance of Midline Involvement in Oral Tongue Cancer. American Journal Of Clinical Oncology 2012, 35: 468-473. PMID: 21701377, PMCID: PMC3755371, DOI: 10.1097/coc.0b013e3182195619.Peer-Reviewed Original ResearchConceptsContralateral lymph node metastasisLymph node metastasisOral tongue squamous cell carcinomaTongue squamous cell carcinomaT2-3 diseaseSquamous cell carcinomaNode metastasisClinicopathologic factorsCell carcinomaMidline involvementEnd Results (SEER) dataLymph node statusOral tongue cancerDifferent prognostic classesLateral tumorsT4 tumorsT1 tumorsT3 tumorsT4 lesionsHistologic subtypeT3 lesionsNode statusPrognostic importanceT classificationTongue cancer
1999
Is Lymphadenectomy Necessary for Early Gastric Cancer?
Hochwald S, Brennan M, Klimstra D, Kim S, Karpeh M. Is Lymphadenectomy Necessary for Early Gastric Cancer? Annals Of Surgical Oncology 1999, 6: 664-670. PMID: 10560852, DOI: 10.1007/s10434-999-0664-5.Peer-Reviewed Original ResearchConceptsAssociated with decreased survivalNode-positive tumorsLymph node involvementPositive nodesMultivariate analysisNode involvementExcellent prognosisActuarial 5-year survivalCohort of Western patientsPredictors of nodal diseasePresence of positive nodesRate of positive nodesGastric cancerMedian follow-up timeUnivariate analysis of survivalDisease-specific survivalDied of diseaseProspective data baseAnalysis of survivalEarly gastric cancerEarly gastric carcinomaNodal diseaseT1 tumorsSurgical resectionLimited resection
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