2024
Effect of apixaban versus vitamin K antagonist and aspirin versus placebo on days alive and out of hospital: An analysis from AUGUSTUS
Fanaroff A, Vora A, Wojdyla D, Mehran R, Granger C, Goodman S, Aronson R, Windecker S, Alexander J, Lopes R. Effect of apixaban versus vitamin K antagonist and aspirin versus placebo on days alive and out of hospital: An analysis from AUGUSTUS. American Heart Journal 2024, 280: 60-69. PMID: 39557109, DOI: 10.1016/j.ahj.2024.11.005.Peer-Reviewed Original ResearchConceptsAcute coronary syndromeTime-to-event analysisAtrial fibrillationCoronary syndromeClinical trialsEffect of antithrombotic therapyVitamin K antagonistsProportion of patientsRobust variance estimationRandomized clinical trialsClinical trial endpointsPercutaneous coronary interventionK antagonistsAntithrombotic therapyPoisson regressionTreatment armsFollow-upIschemic eventsPlaceboRate ratiosAntithrombotic agentsTrial endpointsWarfarinCoronary interventionIntervention methodsMaintaining the validity of inference from linear mixed models in stepped-wedge cluster randomized trials under misspecified random-effects structures
Ouyang Y, Taljaard M, Forbes A, Li F. Maintaining the validity of inference from linear mixed models in stepped-wedge cluster randomized trials under misspecified random-effects structures. Statistical Methods In Medical Research 2024, 33: 1497-1516. PMID: 38807552, PMCID: PMC11499024, DOI: 10.1177/09622802241248382.Peer-Reviewed Original ResearchRandom effects structureVariance estimationComplex correlation structureRobust variance estimationFixed effects parametersDegrees of freedom correctionCluster randomized trialEstimates of standard errorsCorrelation structureRandom effectsStepped-wedge cluster randomized trialComprehensive simulation studyLinear mixed modelsStatistical inferenceRandom intercept modelSimulation studyMixed modelsMisspecificationValidity of inferencesRandom interceptContinuous outcomesEstimationComputational challengesIntercept modelStandard error
2020
Revisiting the Spectrum of Bladder Health: Relationships Between Lower Urinary Tract Symptoms and Multiple Measures of Well-Being
Sutcliffe S, Cain C, Bavendam T, Epperson CN, Fitzgerald CM, Gahagan S, Markland AD, Shoham DA, Smith AL, Rudser K, Brubaker L, Mueller E, Hardacker C, Hebert-Beirne J, Lavender M, Burgio K, Lewis C, McGwin, Jr. G, Vaughan C, Rosa Williams B, Lukacz E, La-Coursiere D, Nodora J, Miller J, Chin-I An L, Kane Low L, Harlow B, Brady S, Chu H, Connett J, Constantine M, Fok C, Rockwood T, Berry A, Schmitz K, Stapleton A, Wyman J, James A, Lowder J, Meister M, Rickey L, Camenga D, Cunningham S, Chai T, Lewis J, Palmer M, Kirkali Z, Mullins C, Norton J. Revisiting the Spectrum of Bladder Health: Relationships Between Lower Urinary Tract Symptoms and Multiple Measures of Well-Being. Journal Of Women's Health 2020, 29: 1077-1090. PMID: 32831001, PMCID: PMC7462007, DOI: 10.1089/jwh.2019.8167.Peer-Reviewed Original ResearchConceptsLower urinary tract symptomsUrinary tract symptomsBladder healthTract symptomsDegree of LUTSBoston Area Community Health SurveyIndividual lower urinary tract symptomsPain/discomfortCommunity Health SurveyCross-sectional analysisInstitutional review boardBACH SurveyUrinary symptomsStorage dysfunctionBladder functionBladder conditionPrevalence ratiosRisk factorsHealth SurveyRobust variance estimationBothersome natureHealth spectrumLife impactInformed consentReview board
2019
The Spectrum of Bladder Health: The Relationship Between Lower Urinary Tract Symptoms and Interference with Activities
Sutcliffe S, Bavendam T, Cain C, Epperson CN, Fitzgerald CM, Gahagan S, Markland AD, Shoham DA, Smith AL, Townsend MK, Rudser K, Brubaker L, Mueller E, Hardacker C, Hebert-Beirne J, Lavender M, Burgio K, Lewis C, McGwin G, Williams B, Lukacz E, LaCoursiere D, Nodora J, Miller J, Chin-I An L, Low L, Harlow B, Brady S, Connett J, Chu H, Fok C, Lindberg S, Rockwood T, Newman D, Berry A, Schmitz K, Stapleton A, Wyman J, McNicholas C, James A, Lowder J, Rickey L, Camenga D, Chai T, Lewis J, Palmer M, Kirkali Z, Mullins C, Norton J. The Spectrum of Bladder Health: The Relationship Between Lower Urinary Tract Symptoms and Interference with Activities. Journal Of Women's Health 2019, 28: 827-841. PMID: 31058573, PMCID: PMC6590721, DOI: 10.1089/jwh.2018.7364.Peer-Reviewed Original ResearchConceptsBladder health promotionBladder healthPrevalence ratiosHealth promotionBoston Area Community Health SurveyLower urinary tract symptomsUrinary tract symptomsCommunity Health SurveyLUTS preventionTract symptomsUrgency incontinenceBladder functionEligible participantsIntermediate healthRisk factorsSymptom preventionHealth SurveyRobust variance estimationLUTSPoor healthHealth definitionsIncontinencePreventionDaily activitiesHealth
2018
Cashew Nut Consumption Increases HDL Cholesterol and Reduces Systolic Blood Pressure in Asian Indians with Type 2 Diabetes: A 12-Week Randomized Controlled Trial
Mohan V, Gayathri R, Jaacks LM, Lakshmipriya N, Anjana RM, Spiegelman D, Jeevan RG, Balasubramaniam KK, Shobana S, Jayanthan M, Gopinath V, Divya S, Kavitha V, Vijayalakshmi P, Bai R M, Unnikrishnan R, Sudha V, Krishnaswamy K, Salas-Salvadó J, Willett WC. Cashew Nut Consumption Increases HDL Cholesterol and Reduces Systolic Blood Pressure in Asian Indians with Type 2 Diabetes: A 12-Week Randomized Controlled Trial. Journal Of Nutrition 2018, 148: 63-69. PMID: 29378038, DOI: 10.1093/jn/nxx001.Peer-Reviewed Original ResearchConceptsSystolic blood pressureBlood pressureNut consumptionBody weightAsian IndiansHDL cholesterolDiabetic dietNut supplementationSelf-reported dietary intakeStandard diabetic dietClinical Trials RegistryHDL cholesterol concentrationsPlasma HDL cholesterolType 2 diabetesCashew nut consumptionBlood lipidsControlled TrialsTrials RegistryGlycemic variablesLipid variablesDietary intakeIntervention groupLipid profileCardiovascular diseaseRobust variance estimation
2013
Validity of Exchangeable Solute Balance as a Measure of Blood Volume in Neurologically Injured Adults
Joffe AM, Healey L, Khandelwal N, Hallman MR, Van Cleve W, Treggiari MM. Validity of Exchangeable Solute Balance as a Measure of Blood Volume in Neurologically Injured Adults. Neurocritical Care 2013, 21: 102-107. PMID: 24057812, DOI: 10.1007/s12028-013-9915-1.Peer-Reviewed Original ResearchConceptsBlood volumeFluid balanceNeuroscience intensive care unitBV measurementsExtracellular fluidConsecutive adult patientsLarge academic medical centerIntensive care unitAcademic medical centerBV testResults55 patientsAdult patientsRoutine careCare unitTotal body waterCapillary leakActual blood volumeMedical CenterRobust variance estimationBVA-100MethodsThe UniversityAlbumin injectionNumber of daysPatientsBody water
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