2025
Efficacy of beta-blocker agents on clinical outcomes in patients with thoracic aortic aneurysm: A systematic review and meta-analysis of randomized controlled trials
Tanriverdi L, Barrett A, Kalyanasundaram A, Zafar M, Ziganshin B, Elefteriades J. Efficacy of beta-blocker agents on clinical outcomes in patients with thoracic aortic aneurysm: A systematic review and meta-analysis of randomized controlled trials. Vascular Pharmacology 2025, 159: 107494. PMID: 40204023, DOI: 10.1016/j.vph.2025.107494.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmRandomized Controlled TrialsPooled risk ratioB-blockersAortic dissectionClinical outcomesAortic aneurysmRisk ratioRisk of aortic dissectionMeta-analysis of randomized controlled trialsControlled TrialsB-blocker treatmentCompared to placeboBeta-blocking agentsCochrane Risk of Bias 2 toolRisk of Bias 2 toolRobust randomized controlled trialsInverse variance-weighted random-effects modelRisk of bias assessmentRandom-effects modelEvidence of benefitSystematic literature searchAortic eventsEvidence-based recommendationsFollow-up
2024
Efficacy of beta blockers in patients with thoracic aortic aneurysm: meta-analysis of randomized controlled trials
Tanriverdi L, Barrett A, Kalyanasundaram A, Zafar M, Ziganshin B, Elefteriades J. Efficacy of beta blockers in patients with thoracic aortic aneurysm: meta-analysis of randomized controlled trials. European Heart Journal 2024, 45: ehae666.2256. DOI: 10.1093/eurheartj/ehae666.2256.Peer-Reviewed Original ResearchThoracic aortic aneurysmRandomized Controlled TrialsPooled risk ratioB-blockersAortic aneurysmAortic dissectionControlled TrialsAortic eventsRisk ratioPrimary outcomePooled risk estimatesRisk of aortic dissectionRisk of bias assessmentNo treatmentMeta-analysis of randomized controlled trialsInverse variance-weighted random-effects modelMeta-analysisLiterature searchB-blocker treatmentSystematic review protocolInternational Prospective RegisterCochrane Central Register of Controlled TrialsEfficacy of beta blockersCentral Register of Controlled TrialsSummary effect measuresThe Role of Negative Pressure Wound Therapy in Temporizing Traumatic Wounds before Lower Limb Soft Tissue Reconstruction: A Systematic Review
Barone N, Ziolkowski N, Haykal S. The Role of Negative Pressure Wound Therapy in Temporizing Traumatic Wounds before Lower Limb Soft Tissue Reconstruction: A Systematic Review. Plastic & Reconstructive Surgery Global Open 2024, 12: e6003. PMID: 39071768, PMCID: PMC11281775, DOI: 10.1097/gox.0000000000006003.Peer-Reviewed Original ResearchSoft tissue reconstructionSoft tissue coverageWound therapyTissue reconstructionTissue coverageFlap loss rateComprehensive search of MEDLINEDelayed union rateNegative pressure wound therapyDefinitive soft tissue coverageFollow-up lengthLeg woundsAdult surgical patientsSystematic reviewDefinitive soft tissue reconstructionSearch of MEDLINERisk of bias assessmentTemporal woundTraumatic woundsAdult patientsSurgical patientsNonunion rateBone unionUnion rateCochrane LibraryReducing self-harm in adolescents: the RISA-IPD individual patient data meta-analysis and systematic review
Cottrell D, Wright-Hughes A, Farrin A, Walwyn R, Mughal F, Truscott A, Diggins E, Irving D, Fonagy P, Ougrin D, Stahl D, Wright J. Reducing self-harm in adolescents: the RISA-IPD individual patient data meta-analysis and systematic review. Health Technology Assessment 2024, 1-42. PMID: 39024118, DOI: 10.3310/gtnt6331.Peer-Reviewed Original ResearchRepetition of self-harmNational Institute for Health and Care ResearchIndividual Patient Data Meta-AnalysisPatient data meta-analysisData Meta-AnalysisSelf-harmSample of participantsSystematic reviewMeta-analysisMeta-analysesPrimary outcomeRisk of bias assessmentLow risk of biasHistory of self-harmPreferred Reporting ItemsReduce self-harmRandomised controlled trialsRisk of biasConventional meta-analysesIndividual patient dataCare researchPublic health concernEligible participantsClinical servicesIssues of research design
2020
Efficacy and acceptability of pharmacological and non-pharmacological interventions for non-specific chronic low back pain: a protocol for a systematic review and network meta-analysis
Thompson T, Dias S, Poulter D, Weldon S, Marsh L, Rossato C, Shin J, Firth J, Veronese N, Dragioti E, Stubbs B, Solmi M, Maher C, Cipriani A, Ioannidis J. Efficacy and acceptability of pharmacological and non-pharmacological interventions for non-specific chronic low back pain: a protocol for a systematic review and network meta-analysis. Systematic Reviews 2020, 9: 130. PMID: 32503666, PMCID: PMC7275431, DOI: 10.1186/s13643-020-01398-3.Peer-Reviewed Original ResearchConceptsChronic low back painNon-specific chronic low back painLow back painBack painNetwork Meta-AnalysisTreatment of non-specific chronic low back painBurden of chronic low back painRandomised controlled trials of interventionsConduct risk of bias assessmentControlled trials of interventionsPrimary care guidelinesPrimary care treatmentPatient-reported pain ratingsRisk of bias assessmentTrials of interventionsNon-pharmacological interventionsMeta-analysisRandomised controlled trialsQuality of lifeTreatment decisionsClinical Trials RegistryComprehensive evidence baseCare guidelinesFunctional abilityHumanistic burden
2016
Protein Intake and Bone Mineral Density‐ a Systematic Review and Meta‐Analysis of Randomized Controlled Trials
Shams‐White M, Sackey J, Fu Z, Karlsen M, Du M, Insogna K, LeBoff M, Shapses S, Weaver C, Chung M. Protein Intake and Bone Mineral Density‐ a Systematic Review and Meta‐Analysis of Randomized Controlled Trials. The FASEB Journal 2016, 30 DOI: 10.1096/fasebj.30.1_supplement.678.6.Peer-Reviewed Original ResearchBone mineral densityRisk of bias assessmentRandomized Controlled TrialsProtein intakeMeta-analysis resultsSystematic reviewBMD lossBias assessmentMeta-analysisFemoral neck bone mineral densityBone mineral density siteBone mineral density outcomesNeck bone mineral densityTotal hipMeta-analysis of randomized controlled trialsControlled TrialsSpine BMD lossRandom-effects meta-analysesPlant protein intakeFull-text screeningPost-menopausal womenHealthy adultsAttenuating BMD lossEffects meta-analysesHigher protein intake
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